Hemodynamics of aneurysm intervention with different stents

An ideal cerebral aneurysm model with different stent forms is established. By using the single-relaxation-time (SRT) lattice Boltzmann method (LBM) to solve the flow field, the blood flow characteristics in the aneurysm under different conditions are studied numerically. The intra-arterial stenting of saccular aneurysms at different Reynolds numbers and the feasibility of new stenting forms such as double stenting and variable-spacing stenting in the aneurysms are explored. The hemodynamic factors such as velocity distribution and wall shear stress (WSS) in the aneurysm are analyzed. Numerical results show that the risk of aneurysm rupture is mainly centralized at the right corner of the aneurysm. Intervention of stents in the aneurysm can effectively reduce the intra-aneurysmal velocity and WSS, and decrease the danger of aneurysm rupture during strenuous exercise or emotional excitement. At the same time, the intervention of a double stent and the stent shape with a dense anterior part in the aneurysm has certain advantages in preventing aneurysm rupture. The intra-aneurysmal mean velocity reduction can reach 90.39% and 80.29% after the intervention of the double stent and the anterior densified stent respectively.     

分叉血管处宽颈动脉瘤的血液动力学分析

考虑血管壁的弹性变形因素，基于临床上某患者的分叉血管处宽颈动脉瘤，建立了分叉血管处宽颈动脉瘤的流固耦合模型。采用计算流体动力学(CFD)数值模拟的方法，研究了脉动条件下个性化分叉血管处宽颈动脉瘤内血液流动特性，分析了分叉血管处宽颈动脉瘤内的血流速度分布特征、壁面压力、壁面切应力等血液动力学影响因素。研究结果表明，脉动周期内，血管分叉处易促成动脉瘤的生长与发展，宽颈动脉瘤的瘤颈与瘤顶处破裂风险较大。