A type III porous-thermo-elastic problem with quasi-static microvoids

Meccanica - In this work we study, from the numerical point of view, a one-dimensional thermoelastic problem where the thermal law is of type III. Quasi-static microvoids are also assumed within...     

Dark and bright soliton solutions and computational modeling of nonlinear regularized long wave model

Nonlinear Dynamics - In this article, the authors simulate and study dark and bright soliton solutions of 1D and 2D regularized long wave (RLW) models. The RLW model occurred in various fields such...     

A dried blood spot assay with HPLC–MS/MS for the determination of larotrectinib in mouse blood and its application to a pharmacokinetic study

Larotrectinib is a first-generation tropomyosin kinase inhibitor, approved for the treatment of solid tumors. In this paper, we present a validated dried blood spot (DBS) method for the quantitation of larotrectinib from mouse blood using HPLC–MS/MS, which was operated under multiple reaction monitoring mode. To the DBS disc cards, acidified methanol enriched with internal standard (IS; enasidenib) was added and extracted using tert-butyl methyl ether as an extraction solvent with sonication. Chromatographic separation of larotrectinib and the IS was achieved on an Atlantis dC₁₈ column using 10 mm ammonium formate–acetonitrile (30:70, v/v) delivered at a flow-rate of 0.80 ml/min. Under these optimized conditions, the retention times of larotrectinib and the IS were ~0.93 and 1.37 min, respectively. The total run time was 2.50 min. Larotrectinib and the IS were analyzed using positive ion scan mode and parent–daughter mass to charge ion (m/z) transitions of 429.1 → 342.1 and 474.1 → 267.1, respectively, were used for the quantitation. The calibration range was 1.06–5,080 ng/ml. No matrix effect or carryover was observed. Hematocrit did not influence DBS larotrectinib concentrations. All of the validation parameters met the acceptance criteria. The applicability of the validated method was shown in a mouse pharmacokinetic study.     

Polarized Lidar Reflectance Measurements of Vegetation at Near-Infrared and Green Wavelengths

There is growing interest in the use of lidar for remote sensing of vegetation owing to the emergence of reliable and rugged lasers and highly sensitive detectors. Lidar remote sensing has a distinct advantage over conventional techniques in vegetation remote sensing due to its capability for three-dimensional characterization of vegetative targets. The Multiwavelength Airborne Polarimetric Lidar (MAPL) system was developed primarily for vegetation remote sensing applications from an airborne platform of up to 1,000 -m altitude. The lidar system has full waveform capture and polarimetric measurement capability at two wavelengths in the near-infrared (1064 nm) and the green (532 nm) spectral regions. This study presents preliminary ground-based lidar reflectance measurements on a variety of deciduous and coniferous trees under fully foliated conditions with a view towards tree species discrimination. Variations in the reflectance characteristics of selected deciduous trees under unfoliated and fully foliated conditions were also investigated. Our study reveals distinct differences in the reflectance characteristics of various trees.     

Affine Hecke algebras and the Schubert calculus

Using a combinatorial approach that avoids geometry, this paper studies the structure of K_T(G/B), the T-equivariant K-theory of the generalized flag variety G/B. This ring has a natural basis (the double Grothendieck polynomials), where is the structure sheaf of the Schubert variety X_w. For rank two cases we compute the corresponding structure constants of the ring K_T(G/B) and, based on this data, make a positivity conjecture for general G which generalizes the theorems of M. Brion (for K(G/B)) and W. Graham (for H_T^*(G/B)). Let [X^λ]K_T(G/B) be the class of the homogeneous line bundle on G/B corresponding to the character of T indexed by λ. For general G we prove “Pieri–Chevalley formulas” for the products , , , and , where λ is dominant. By using the Chern character and comparing lowest degree terms the products which are computed in this paper also give results for the Grothendieck polynomials, double Schubert polynomials, and ordinary Schubert polynomials in, respectively K(G/B), H_T^*(G/B) and H^*(G/B).     

On the possibility of designing interacting semiconductor quantum wells with zero perturbation coupling

The paper describes the possibility of designing matched interacting semiconductor quantum wells. It is shown that for a given eigenstate of a quantum well (QW), it is always possible to find another QW in such a way that the coupling leaves the original eigenstate of the host QW unperturbed irrespective of the strength of interaction. For rectangular QWs, the condition is met with whenever the second QW has appropriate width and depth so that phase travelled by an electron wave through it is an integral multiple of π.     

An elementary proof of the uniqueness of invariant product measures for some infinite dimensional processesUne preuve élémentaire de l'unicité des mesures invariantes produits pour certains processus en dimension infinie

Consider an infinite dimensional diffusion process with state space , where T is the circle, and defined by an infinitesimal generator L which acts on local functions f as . Suppose that the coefficients a_i and b_i are smooth, bounded, of finite range, have uniformly bounded second order partial derivatives, that a_i are uniformly bounded from below by some strictly positive constant, and that a_i is a function only of η_i. Suppose that there is a product measure ν which is invariant. Then if ν is the Lebesgue measure or if d=1,2, it is the unique invariant measure. Furthermore, if ν is translation invariant, it is the unique invariant, translation invariant measure. The proofs are elementary. Similar results can be proved in the context of an interacting particle system with state space , with uniformly positive bounded flip rates which are finite range. To cite this article: A.F. Ram??rez, C. R. Acad. Sci. Paris, Ser. I 334 (2002) 139–144     

Calculated elastic constants of dilute alloys based on bcc metals

The elastic constants of dilute alloys based on bcc metals have been calculated using the Green’s function method obtaining explicit expressions for change in elastic constants in terms oft-matrix. The crystal impurity problem is discussed within an impurity model containing central and non-central force constant changes extended up to second neighbours of the impurity. The effect of volume change on elastic constants and a contribution from electron pressure term are considered. Numerical results for changes in three elastic moduli have been presented for a number of dilute alloys based on Mo, Nb, W, Ta and V.