排序方式: 共有10条查询结果,搜索用时 15 毫秒
1
1.
Latifeh Navidpour Leila Karimi Mohsen Amini Mohssen Vosooghi Abbas Shafiee 《Journal of heterocyclic chemistry》2004,41(2):201-204
Arylation of the readily available 3‐alkythio‐5‐aryl‐1,2,4‐triazoles gave 5‐alkylthio‐1,3‐diaryl‐1,2,4‐triazoles in moderate yield. The structures of the latter were confirmed by NOE and 13C‐NMR. 相似文献
2.
Synthetic Approaches towards the Sulfonamide Substituted‐1,5‐Diarylimidazole‐2‐thiones as Selective Cyclooxygense‐2 inhibitors 下载免费PDF全文
Latifeh Navidpour Mohsen Amini Ramin Miri Omidreza Firuzi Marjan Tavakkoli Abbas Shafiee 《Journal of heterocyclic chemistry》2014,51(1):71-79
A new series of sulfonamide substituted 1,5‐diarylimidazole, possessing C‐2 alkylthio moiety, were synthesized for their cyclooxygense‐2 (COX‐2) inhibitory activity starting from condensation of N,N‐dibenzylaminosulfonylphenacylamine hydrochloride ( 2 ) and corresponding isothiocyanate in the presence of Et3N, followed by alkylation in the basic medium. In concomitant with these intermediates, 2‐arylamino‐5‐arylthiazole derivatives 5 were also produced. The ratio of these two products was variable with different isothiocyanates. Final debenzylation was achieved using concentrated sulfuric acid to give the title sulfonamides 8 . 相似文献
3.
A convenient synthesis of 5‐alkylthio‐3,4‐diarylisoxazoles by palladium‐catalyzed coupling reactions
Roozbeh Eskandari Latifeh Navidpour Mohsen Amini Abbas Shafiee Hamed Shafaroodi Abbas Shafiee 《Journal of heterocyclic chemistry》2007,44(2):449-453
Palladium‐catalyzed coupling reaction was found effective for rapid access to pharmacologically interesting 3,4‐diarylisoxazoles derivatives as selective COX‐2 inhibitors. Thus, the coupling reaction between 5‐alkylthio‐3‐aryl‐4‐iodoisoxazoles and arylboronic acids afforded the target 5‐alkylthio‐3,4‐diarylisoxazoles in good yields. 相似文献
4.
Yadollah Yamini Shahram Seidi Farzad Latifeh 《International journal of environmental analytical chemistry》2017,97(13):1223-1236
In the present study, ionic liquid-modified silica-coated magnetic nanoparticles (MNPs) were synthesised and applied as a new anion-exchange sorbent for extraction and determination of Cr(VI) followed by inductively coupled plasma atomic emission spectrometry. The characterisation of MNPs was carried out by scanning electron microscope, Fourier transform infrared and vibrating sample magnetometer. Experimental design and response surface methodology were used for optimisation of different parameters which affect extraction efficiency of Cr(VI). Under the optimised conditions, extraction recoveries within the range of 25–33% with relative standard deviations (RSD%, n = 4) within the range of 3.0–5.0% were obtained. The limit of detection was found to be 0.1 µg L?1. The linearity was studied in the range of 0.5-200 µg L?1 with the determination coefficient of 0.9958. Also, calculated Errors% for determination of Cr(VI) in the range of 5-15 depict that the method offers acceptable accuracy for analysis of Cr(VI). The method was successfully applied for extraction and determination of Cr(VI) selectively in some tannery waste water samples. 相似文献
5.
The first synthesis of sulfonamide and sulfonate analogues of a sulfated carbohydrate in which the ester oxygen of the sulfate is replaced with a CHF or CF2 group is reported. This was accomplished by electrophilic fluorination of the protected sulfonate and sulfonamide precursors. [reaction: see text]. 相似文献
6.
Saadati-Eskandari Naghmeh Navidpour Latifeh Yaghmaei Parichehreh Ebrahim-Habibi Azadeh 《Applied biochemistry and biotechnology》2019,189(1):305-317
Applied Biochemistry and Biotechnology - The effect of 16 amino acids (AA) with various physicochemical properties was investigated on human lysozyme (HL) heat-induced amorphous aggregation.... 相似文献
7.
Extraction and preconcentration of formaldehyde in water by polypyrrole‐coated magnetic nanoparticles and determination by high‐performance liquid chromatography 下载免费PDF全文
Meysam Safari Yadollah Yamini Elham Tahmasebi Farzad Latifeh 《Journal of separation science》2015,38(19):3421-3427
In this study, a simple and rapid extraction method based on the application of polypyrrole‐coated Fe3O4 nanoparticles as a magnetic solid‐phase extraction sorbent was successfully developed for the extraction and preconcentration of trace amounts of formaldehyde after derivatization with 2,4‐dinitrophenylhydrazine. The analyses were performed by high‐performance liquid chromatography followed by UV detection. Several variables affecting the extraction efficiency of the formaldehyde, i.e., sample pH, amount of sorbent, salt concentration, extraction time and desorption conditions were investigated and optimized. The best working conditions were as follows: sample pH, 5; amount of sorbent, 40 mg; NaCl concentration, 20% w/v; sample volume, 20 mL; extraction time, 12 min; and 100 μL of methanol for desorption of the formaldehyde within 3 min. Under the optimal conditions, the performance of the proposed method was studied in terms of linear dynamic range (10–500 μg/L), correlation coefficient (R2 ≥ 0.998), precision (RSD% ≤ 5.5) and limit of detection (4 μg/L). Finally, the developed method was successfully applied for extraction and determination of formaldehyde in tap, rain and tomato water samples, and satisfactory results were obtained. 相似文献
8.
M. Shekarchi M. Pirali-Hamedani L. Navidpour N. Adib A. Shafiee 《Journal of the Iranian Chemical Society》2008,5(1):150-158
A new series of 3-aryl-5-(pyridin-3-yl)-1-thiocarbamoyl-2-pyrazoline derivatives (4a-j) were prepared by the reaction of azachalcons 3a-j with thiosemicarbazide in ethanolic sodium hydroxide. The structure of synthesized compounds were confirmed by 1H NMR and Mass spectral data. Their antibacterial activities against Escherichia coli (CTP 7624), Staphylococcus aureus (ATCC 6538), Staphylococcus epidermidis (ATCC 12229), Pseudomonas aeruginosa (ATCC 9027), Bacillus subtilis (ATCC 1156) and Micrococcus luteus (ATCC 9341) were investigated. Antifungal activity of compounds against Candida albicans and Candida globrata were found to be inactive. Compounds 4a-j were also evaluated for antituberculosis activity against Mycobacterium tuberculosis H 37 Rv (ATCC 27294) in BACTEC 12B using a broth microdilution assay and Microplate Alamar Blue Assay (MABA). The preliminary results showed that compounds 4e, 4d and 4g had 87%, 93% and 92% inhibitory effect respectively. 相似文献
9.
Latifeh Navidpour Mohsen Amini Abbas Shafiee 《Journal of heterocyclic chemistry》2007,44(6):1323-1331
A new series of 3‐alkylthio‐4,5‐diaryl‐4H‐1,2,4‐triazoles having a SO2NH2 substituent in the para‐position on one of the aryl rings ( 19/25 ) were prepared starting from the appropriate benzoic acid hydrazides ( 15/21 ). Reaction of the corresponding hydrazides with the appropriate isothiocyanates yielded 16/22 , which were cyclized in basic media to give 4,5‐diaryl‐2,4‐dihydro‐3H‐1,2,4‐triazole‐3‐thiones 17/23 . Alkylation of 17/23 afforded the alkylthio compounds 18/24 . Final debenzylation was achieved with concentrated sulfuric acid to give the target sulfonamides 19/25 . 相似文献
10.
Maryam Allahyari-Devin Behnam Abedi Latifeh Navidpour Abbas Shafiee 《Journal of the Iranian Chemical Society》2013,10(1):43-53
A new series of N-hydroxyethylpyrazole (12a–f) and N-hydroxymethylpyrazole derivatives (15a–f) were designed for their estrogenic activities, having a 11.0 ± 0.5 Å distance between their two hydroxyl groups, aliphatic–OH and phenolic–OH similar to 17β-estradiol (E2) as an endogenous hormone. To synthesize the title compounds, the key intermediate 1,3-dicarbonyl derivatives (2 and 8), were treated with hydrazine hydrate to produce the pyrazole ring 5 and 9. Further hydroxyalkylation of the latter produced the title pyrazoles. The position of hydroxyethyl or hydroxymethyl substituents in the products was determined through 2D NOE NMR spectroscopy. 相似文献
1