Karl-Heinz Meiwes-Broer (ed) Metal clusters at surfaces: structure,quantum properties,physical chemistry (Springer Series in Cluster Physics)

Journal of Solid State Electrochemistry -     

CXCR4 Stimulates Macropinocytosis: Implications for Cellular Uptake of Arginine-Rich Cell-Penetrating Peptides and HIV

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Highlights? CXCR4 was identified as a receptor to stimulate cellular uptake of R12 peptide ? Interaction with R12 stimulates internalization of CXCR4 via macropinocytosis ? SDF-1α and HIV-1 gp120 protein also induce macropinocytosis ? Macropinocytic uptake of HIV-1 diminished the infection of host cells     

W. Ekardt (ed): Metal clusters. (Wiley Series in Theoretical Chemistry)

Journal of Solid State Electrochemistry -     

Intermolecular interactions in condensed matter

Recent progress in Fourier transform IR and far IR investigation of intermolecular interactions in liquid solutions and cryogenic matrices will be reported. Particular emphasis is given to routine performance checks of the spectrometer and to novel techniques of sample preparation and related equipment. The described examples are the dynamics of H₂O isolated in solid Ar and the aggregational behaviour of HCN and CH₃CN in diverse liquid and solid phases.     

Adsorption of small organic molecules on anatase and rutile surfaces: a theoretical study

The adsorption of several small organic molecules on rutile (110) and (100) as well as on anatase (101) surfaces was investigated by Car-Parrinello molecular dynamics in aqueous solution and a new approach to the calculation of adsorption energies is proposed, taking into account the potential energy fluctuation of larger systems. Acetylene and ethylene insert into twin oxygen vacancies in the surface and form polarized covalent Ti-C bonds. In one case spontaneous coupling of two acetylene molecules to a C(4)H(3) molecule with a structure similar to trans-butadiene was observed. Neutral catechol and the singly charged anion were not reactive on any titanium dioxide surface, but the twofold-charged anion attained stable mono- and bidentated geometries on anatase. Methanol, ethanol, formaldehyde and acetaldehyde adsorbed with their functional groups. Very stable geometries provide a Ti-O bond and have adsorption energies of 60-200 kJ/mol. The adsorbates compete with water molecules for similar adsorption sites in point defects as well as on perfect surfaces.     

Intermittent simulated moving bed chromatography: 3. Separation of Tröger's base enantiomers under nonlinear conditions

One of the modified simulated moving bed (SMB) processes, the intermittent SMB (I-SMB) process, has been recently analyzed theoretically [1] and its superior performance compared to the conventional SMB process has been demonstrated at a rather low total feed concentration through experiments and simulations [2]. This work shows that the I-SMB process outperforms the conventional SMB process also at high feed concentration where the species are clearly subject to a nonlinear adsorption isotherm. In the case of the separation of the Tröger's base's enantiomers in ethanol on ChiralPak AD, the two processes operated in a six-column 1-2-2-1 configuration (one column in sections 1 and 4 and two columns in sections 2 and 3) and in a four-column 1-1-1-1 configuration (one column in each section) are compared at high feed concentration through both experiments and simulations. Even under nonlinear conditions the four column I-SMB process can successfully separate the two enantiomers achieving purity levels as high as the two six column processes and exhibiting better productivity.