全文获取类型
收费全文 | 263篇 |
免费 | 15篇 |
专业分类
化学 | 199篇 |
晶体学 | 4篇 |
力学 | 6篇 |
数学 | 8篇 |
物理学 | 61篇 |
出版年
2023年 | 6篇 |
2022年 | 5篇 |
2021年 | 4篇 |
2020年 | 5篇 |
2019年 | 7篇 |
2018年 | 4篇 |
2017年 | 2篇 |
2016年 | 8篇 |
2015年 | 7篇 |
2014年 | 4篇 |
2013年 | 15篇 |
2012年 | 20篇 |
2011年 | 13篇 |
2010年 | 14篇 |
2009年 | 11篇 |
2008年 | 16篇 |
2007年 | 24篇 |
2006年 | 12篇 |
2005年 | 14篇 |
2004年 | 10篇 |
2003年 | 12篇 |
2002年 | 10篇 |
2001年 | 4篇 |
2000年 | 6篇 |
1999年 | 1篇 |
1998年 | 3篇 |
1997年 | 3篇 |
1995年 | 3篇 |
1994年 | 1篇 |
1993年 | 4篇 |
1992年 | 3篇 |
1991年 | 2篇 |
1989年 | 1篇 |
1987年 | 2篇 |
1986年 | 1篇 |
1984年 | 1篇 |
1982年 | 2篇 |
1979年 | 1篇 |
1978年 | 1篇 |
1977年 | 2篇 |
1976年 | 1篇 |
1975年 | 1篇 |
1973年 | 3篇 |
1970年 | 1篇 |
1968年 | 1篇 |
1966年 | 1篇 |
1965年 | 3篇 |
1963年 | 2篇 |
1926年 | 1篇 |
排序方式: 共有278条查询结果,搜索用时 31 毫秒
1.
Dr. Soichiro Ogi Aiko Takamatsu Kentaro Matsumoto Shintaro Hasegawa Prof. Dr. Shigehiro Yamaguchi 《Angewandte Chemie (International ed. in English)》2023,62(34):e202306428
We have investigated the folding and assembly behavior of a cystine-based dimeric diamide bearing pyrene units and solubilizing alkyl chains. In low-polarity solvents, it forms a 14-membered ring through double intramolecular hydrogen bonds between two diamide units. The spectroscopic studies revealed that the folded state is thermodynamically unstable and eventually transforms into more energetically stable helical supramolecular polymers that show an enhanced chiral excitonic coupling between the transition dipoles of the pyrene units. Importantly, compared to an alanine-based monomeric diamide, the dimeric diamide exhibits a superior kinetic stability in the metastable folded state, as well as an increased thermodynamic stability in the aggregated state. Accordingly, the initiation of supramolecular polymerization can be regulated using a seeding method even under microfluidic mixing conditions. Furthermore, taking advantage of a self-sorting behavior observed in a mixture of l -cysteine- and d -cysteine-based dimeric diamides, a two-step supramolecular polymerization was achieved by stepwise addition of the corresponding seeds. 相似文献
2.
Hiroshi Mizoguchi SangWon Park Haruhiro Hiraka Kazutaka Ikeda Toshiya Otomo Hideo Hosono 《Angewandte Chemie (Weinheim an der Bergstrasse, Germany)》2015,127(10):2975-2978
Using a high pressure technique and the strong donating nature of H−, a new series of tetragonal La2Fe2Se2O3‐type layered mixed‐anion arsenides, Ln2M2As2Hx, was synthesized (Ln=La or Sm, M=Ti, V, Cr, or Mn; x≈3). In these compounds, an unusual M2H square net, which has anti CuO2 square net structures accompanying two As3− ions, is sandwiched by (LaH)2 fluorite layers. Notably, strong metal–metal bonding with a distance of 2.80 Å was confirmed in La2Ti2As2H2.3, which has metallic properties. In fact, these compounds are situated near the boundary between salt‐like ionic hydrides and transition‐metal hydrides with metallic characters. 相似文献
3.
Suenaga Yuma Kawano Hiroaki Takamatsu Toshihiro Matsumura Yuriko Ito Norihiko Iwasawa Atsuo Okino Akitoshi 《Plasma Chemistry and Plasma Processing》2022,42(3):575-586
Plasma Chemistry and Plasma Processing - Atmospheric low-temperature plasma has received attention for application in disinfection methods. In this study, we develop a plasma bubbling method as a... 相似文献
4.
5,11-Diazadibenzo[hi,qr]tetracene: Synthesis,Properties, and Reactivity toward Nucleophilic Reagents
Dr. Keisuke Fujimoto Satoshi Takimoto Shota Masuda Dr. Toshiyasu Inuzuka Kazutaka Sanada Prof. Dr. Masami Sakamoto Prof. Dr. Masaki Takahashi 《Chemistry (Weinheim an der Bergstrasse, Germany)》2021,27(35):8951-8955
5,11-Diazadibenzo[hi,qr]tetracene was synthesized as a new nitrogen-substituted polycyclic heteroaromatic compound by Pd-catalyzed cycloisomerization of an alkyne precursor followed by oxidative cyclization with bis(trifluoroacetoxy)iodobenzene. The substitution of imine-type nitrogen atoms significantly enhanced its electron-accepting character and facilitated the direct nucleophilic addition of arylamines under strongly basic conditions to afford the desired amino-substituted products. The introduction of amino groups induced a remarkable red-shift in their absorption spectra; the tetrasubstituted product exhibited intense near-infrared absorbing property. Furthermore, the π-electronic system, which includes a redox-active 1,4-diazabutadiene moiety, underwent reversible interconversion to its corresponding reduced form upon reduction with NaBH4 and aerobic oxidation. 相似文献
5.
A simple high‐performance liquid chromatography for the determination of linezolid in human plasma and saliva 下载免费PDF全文
Shuuji Hara Masanobu Uchiyama Masami Yoshinari Taichi Matsumoto Shiro Jimi Atsushi Togawa Tohru Takata Yasushi Takamatsu 《Biomedical chromatography : BMC》2015,29(9):1428-1431
Linezolid is an antimicrobial agent for the treatment of multiresistant Gram‐positive infections. A practical high‐performance liquid chromatography method was developed for the determination of linezolid in human plasma and saliva. Linezolid and an internal standard (o‐ethoxybenzamide) were extracted from plasma and saliva with ethyl acetate and analyzed on a Capcell Pak C18 MG column with UV detection at 254 nm. The calibration curve was linear through the range 0.5–50 µg/mL using a 200 μL sample volume. The intra‐ and interday precisions were all <6.44% for plasma and 5.60% for saliva. The accuracies ranged from 98.8 to 110% for both matrices. The mean recoveries of linezolid were 80.8% for plasma and 79.0% for saliva. This method was used to determine the plasma and saliva concentrations of linezolid in healthy volunteers who were orally administered a 600 mg dose of linezolid. Our liquid–liquid extraction procedure is easy and requires a small volume of plasma or saliva (200 μL). This small volume can be advantageous in clinical pharmacokinetic studies, especially if children participate. Copyright © 2015 John Wiley & Sons, Ltd. 相似文献
6.
Shibo Xu Kazutaka Takamatsu Prof. Dr. Koji Hirano Prof. Dr. Masahiro Miura 《Chemistry (Weinheim an der Bergstrasse, Germany)》2019,25(40):9400-9404
A NiCl2(PEt3)2-catalyzed regioselective C−H coupling of 8-aminoquinoline-derived benzamides with oxetanes has been developed. The reaction proceeds with concomitant removal of the 8-aminoquinoline auxiliary to directly form the corresponding seven-membered benzolactones, which frequently occur in natural products and bioactive molecules. Additionally, no stereochemical erosion is observed during the course of the reaction, and the use of enantioenriched and substituted oxetane thus provides a new avenue to the optically active benzolactone. 相似文献
7.
Stereoselective analysis of flecainide enantiomers using reversed‐phase liquid chromatography for assessing CYP2D6 activity 下载免费PDF全文
Kosuke Doki Yukio Sekiguchi Keisuke Kuga Kazutaka Aonuma Yukinao Kohda Masato Homma 《Biomedical chromatography : BMC》2014,28(9):1193-1198
Stereoselective analyses of flecainide enantiomers were performed using reversed‐phase high‐performance liquid chromatography (HPLC) equipped with a polysaccharide‐based chiral column (Chiralpak AS‐RH) and fluorescence detector. Excitation and emission wavelengths were set at 300 and 370 nm, respectively. Flecainide enantiomers in serum and urine were extracted using diethyl ether. The mobile phase solution, comprising 0.1 m potassium hexafluorophosphate and acetonitrile (65:35, v/v), was pumped at a flow rate of 0.5 mL/min. The recoveries of flecainide enantiomers were greater than 94%, with the coefficients of variation (CVs) <6%. The calibration curves of flecainide enantiomers in serum and urine were linear in the concentration range 5–500 ng/mL and 0.75–15 µg/mL (r > 0.999), respectively. CVs in intra‐day and inter‐day assays were 1.8–5.8 and 3.4–7.5%, respectively. In a pharmacokinetic study, the ratios of (S)‐ to (R)‐flecainide (S/R ratio) in the area under the curve and the amount of flecainide enantiomers excreted in urine were lower in a subject carrying CYP2D6*10/*10 than in subjects carrying CYP2D6*1/*2. The S/R ratio of trough serum flecainide concentration ranged from 0.79 to 1.16 in patients receiving oral flecainide. The present HPLC method can be used to assess hepatic flecainide metabolism in a pharmacokinetic study and therapeutic drug monitoring. Copyright © 2014 John Wiley & Sons, Ltd. 相似文献
8.
Kenji Okada Yuichiro Takamatsu Yasuaki Tokudome Atsushi Nakahira Masahide Takahashi 《Journal of Sol-Gel Science and Technology》2013,65(1):36-40
Synthesis of titanate nanotubes (TNTs) from sol–gel derived amorphous TiO2 thin films under moderate hydrothermal condition has been reported. TNTs from film possess a tubular morphology that is the same crystalline phase as one synthesized from TiO2 powder so far. TNTs obtained in this study are not entangled one another but oriented and isolated on the substrate. Growth of highly oriented TNTs is observed in micro grooves of amorphous TiO2 thin film. Their orientation is also maintained with the growth of TNTs. 相似文献
9.
Kazuhiro Kato Hideo OmotoTakao Tomioka Atsushi Takamatsu 《Applied Surface Science》2011,257(21):9207-9212
The influence of high-temperature annealing on the electrical properties and microstructure of tin-doped indium oxide (ITO) thin films was investigated as a function of oxygen gas flow ratio to argon gas during the sputtering deposition. The ITO thin films were annealed at 500 °C in air after the deposition. It was found that the ITO thin films, which were deposited in relatively low oxygen gas flow ratio, exhibited high Hall mobility and low-resistivity after the annealing. Furthermore, the X-ray reflectivity and diffraction measurement revealed that the ITO thin film with low-resistivity after annealing exhibited high packing density, smooth surface and low crystallization degree. It can be considered that the carrier electron scattering was suppressed with increasing in the packing density of the ITO thin film; as a result, the Hall mobility and resistivity were improved. 相似文献
10.
When ultrafast laser pulse strikes the crystal with a van Hove singularity in the phonon density of states, it can create a pair of anti-correlated in wave-vector phonons. As a result, the atomic fluctuations in either position or momentum become squeezed in such a way that their size might fall below the vacuum level. The ultrafast pulses can also generate a biphonon state in which the constituent phonons are correlated and/or entangled. Here we show that via the interplay between one- and two-phonon interference the bound and squeezed two-phonon state in (110) oriented ZnTe single crystal can be manipulated. 相似文献