Macroscopic Polarization Change of Mononuclear Valence Tautomeric Cobalt Complexes Through the Use of Enantiopure Ligand

The crystallization of a complex having electron transfer properties in a polar space group can induce the polarization switching of a crystal in a specific direction, which is attractive for the development of sensors, memory devices, and capacitors. Unfortunately, the probability of crystallization in a polar space group is usually low. Noticing that enantiopure compounds crystallize in Sohncke space groups, this paper reports a strategy for the molecular design of non-ferroelectric polarization switching crystals based on the use of intramolecular electron transfer and chirality. In addition, this paper describes the synthesis of a mononuclear valence tautomeric (VT) cobalt complex bearing an enantiopure ligand. The introduction of enantiomer enables the crystallization of the complex in the polar space group (P2₁). The polarization of the crystals along the b-axis direction is not canceled out and the VT transition is accompanied by a change in the macroscopic polarization of the polar crystal. Polarization switching via electron transfer is realized at around room temperature.     

Experimental study on interfacial area transport of a vertical downward bubbly flow

In relation to the development of the interfacial area transport equation, local flow measurements of vertical downward air–water flows in a pipe with an inner diameter of 50.8 mm were performed at three axial locations of z/D=6.50, 34.0, and 66.5 as well as ten radial locations from r/R=0 to r/R=0.9 using a multi-sensor probe. In the experiment, the superficial liquid velocity and the void fraction ranged from –0.620 m/s to –2.49 m/s and from 0.21% to 8.4%, respectively. The dependence of the interfacial area transport on the liquid velocity, void fraction, and bubble size is discussed in detail.     

Flow regime transition criteria for two-phase flow in a vertical annulus

In this work, a new flow regime transition model is proposed for two-phase flows in a vertical annulus. Following previous works, the flow regimes considered are bubbly (B), slug (S) or cap-slug (CS), churn (C) and annular (A). The B to CS transition is modeled using the maximum bubble package criteria of small bubbles. The S to C transition takes place for small annulus perimeter flow channels and it is assumed to occur when the mean void fraction over the entire region exceeds that over the slug–bubble section. If the annulus perimeter is larger that the distorted bubble limit the cap-slug flow regime will be considered since in these conditions it is not possible to distinguish between cap and partial-slug bubbles. The CS to C transition is modeled using the maximum bubble package criteria. However, this transition considers the coalescence of cap and spherical bubbles in order to take into account the flow channel geometry. Finally, the C to A transition is modeled assuming two different mechanisms, (a) flow reversal in the liquid film section along large bubbles; (b) destruction on liquid slugs or large waves by entrainment or deformation. In the S to C and C to A flow regime transitions the annulus flow channel is considered as a rectangular flow channel with no side walls. In all the modeled transitions the drift-flux model is used to obtain the final correlations. The final equations for every flow regime transition are easy to be implemented in computational codes and not experimental input is needed. The prediction accuracy of the newly developed model has been checked against air–water as well as boiling flow regime maps. In all the cases, the new developed model shows better predicting capabilities than the existing correlations most used in literature.     

Flow regime transition criteria for two-phase flow at reduced gravity conditions

Flow regime transition criteria are of practical importance for two-phase flow analyses at reduced gravity conditions. Here, flow regime transition criteria which take the frictional pressure loss effect into account were studied in detail. Criteria at reduced gravity conditions were developed by extending an existing model from normal gravity to reduced gravity conditions. A comparison of the newly developed flow regime transition criteria model with various experimental datasets taken at microgravity conditions showed satisfactory agreement. Sample computations of the model were performed at various gravity conditions, such as 0.196, 1.62, 3.71 and 9.81 m/s² corresponding to micro-gravity and lunar, Martian and Earth surface gravity, respectively. It was found that the effect of gravity on bubbly–slug and slug–annular (churn) transitions in a two-phase flow system was more pronounced at low liquid flow conditions, whereas the gravity effect could be ignored at high mixture volumetric flux conditions. While for the annular flow transitions due to flow reversal and onset of droplet entrainment, higher superficial gas velocity was obtained at higher gravity level.     

Selective determination of tryptophan-containing peptides through precolumn derivatization and liquid chromatography using intramolecular fluorescence resonance energy transfer detection.

A selective and sensitive fluorometric determination method for native fluorescent peptides has been developed. This method is based on intramolecular fluorescence resonance energy transfer (FRET) detection in a liquid chromatography (LC) system following precolumn derivatization of the amino groups of tryptophan (Trp)-containing peptides. In this detection process, we monitored the FRET from the native fluorescent Trp moieties (donor) to the derivatized fluorophore (acceptor). From a screening study involving 10 fluorescent reagents, we found that o-phthalaldehyde (OPA) generated FRET most effectively. The OPA derivatives of the native fluorescent peptides emitted OPA fluorescence (445 nm) through an intramolecular FRET process when they were excited at the excitation maximum wavelength of the Trp-containing peptides (280 nm). The generation of FRET was confirmed through comparison with the analysis of a non-fluorescent peptide (C-reactive protein fragment (77 - 82)) performed using LC and a three-dimensional fluorescence detection system. We were able to separate the OPA derivatives of the Trp-containing peptides when performing LC on a reversed-phase column. The detection limits (signal-to-noise ratio = 3) for the Trp-containing peptides, at a 20-microL injection volume, were 41 - 180 fmol. The sensitivity of the intramolecular FRET-forming derivatization method is higher than that of the system that takes advantage of the conventional detection of OPA derivatives. Moreover, native non-fluorescent amines and peptides in the sample monitored at FRET detection are weaker than those of conventional fluorescence detection.     

Effect of gravity on axial development of bubbly flow at low liquid Reynolds number

In view of the great importance of two geometrical parameters such as void fraction and interfacial area concentration to the accurate two-phase flow analysis at microgravity conditions, axial developments of flow parameters such as void fraction, interfacial area concentration, bubble Sauter mean diameter, and bubble number density were measured in bubbly flow at microgravity and low liquid Reynolds number conditions where the gravity effect on the flow parameters were pronounced. A total of seven data sets were acquired in the flow range of the void fraction from 1.01% to 3.36% and the liquid Reynolds number from 1,400 to 4,750. The measurements were also performed in the similar flow range at normal gravity conditions. The transport mechanisms of the flow parameters are discussed in detail based on the data measured at normal and microgravity conditions, and the drift-flux model developed at microgravity conditions are compared with the measured data.An erratum to this article can be found at     

On the use of area-averaged void fraction and local bubble chord length entropies as two-phase flow regime indicators

In this work, the use of the area-averaged void fraction and bubble chord length entropies is introduced as flow regime indicators in two-phase flow systems. The entropy provides quantitative information about the disorder in the area-averaged void fraction or bubble chord length distributions. The CPDF (cumulative probability distribution function) of void fractions and bubble chord lengths obtained by means of impedance meters and conductivity probes are used to calculate both entropies. Entropy values for 242 flow conditions in upward two-phase flows in 25.4 and 50.8-mm pipes have been calculated. The measured conditions cover ranges from 0.13 to 5 m/s in the superficial liquid velocity j _f and ranges from 0.01 to 25 m/s in the superficial gas velocity j _g. The physical meaning of both entropies has been interpreted using the visual flow regime map information. The area-averaged void fraction and bubble chord length entropies capability as flow regime indicators have been checked with other statistical parameters and also with different input signals durations. The area-averaged void fraction and the bubble chord length entropies provide better or at least similar results than those obtained with other indicators that include more than one parameter. The entropy is capable to reduce the relevant information of the flow regimes in only one significant and useful parameter. In addition, the entropy computation time is shorter than the majority of the other indicators. The use of one parameter as input also represents faster predictions.     

Flow regime development analysis in adiabatic upward two-phase flow in a vertical annulus

In this work radial and axial flow regime development in adiabatic upward air-water two-phase flow in a vertical annulus has been investigated. Local flow regimes have been identified using conductivity probes and neural networks techniques. The inner and outer diameters of the annulus are 19.1 mm and 38.1 mm, respectively. The equivalent hydraulic diameter of the flow channel, D_H, is 19.0 mm and the total length is 4.37 m. The flow regime map includes 1080 local flow regimes identifications in 72 flow conditions within a range of 0.01 m/s < 〈j_g〉 < 30 m/s and 0.2 m/s < 〈j_f〉 < 3.5 m/s where 〈j_g〉 and 〈j_f〉 are, respectively, superficial gas and liquid velocities. The local flow regime has been classified into four categories: bubbly, cap-slug, churn-turbulent and annular flows. In order to study the radial and axial development of flow regime the measurements have been performed at five radial locations. The three axial positions correspond to z/D_H = 52, 149 and 230, where z represents the axial position. The flow regime indicator has been chosen as some statistical parameters of local bubble chord length distributions and self-organized neural networks have been used as mapping system. This information has been also used to compare the results given by the existing flow regime transition models. The local flow regime is characterized basically by the void fraction and bubble chord length. The radial development of flow regime shows partial and complete local flow regime combinations. The radial development is controlled by axial location and superficial liquid velocity. The radial flow regime transition is always initiated in the center of the flow channel and it is propagated towards the channel boundaries. The axial development of flow regime is observed in all the flow maps and it is governed by superficial liquid velocity and radial location. The prediction results of the models are compared for each flow regime transition.