排序方式: 共有12条查询结果,搜索用时 15 毫秒
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O. V. Serdyuk I. V. Evseenko G. A. Dushenko Yu. V. Revinskii I. E. Mikhailov 《Russian Journal of Organic Chemistry》2012,48(1):78-82
Previously unknown 2-[2-(9-anthryl)vinyl]quinolin-8-ol and 2-[2-(9-anthryl)vinyl]-8-methoxyquinoline were synthesized by condensation
of 8-hydroxy(methoxy)-2-methylquinoline with 9-anthraldehyde in acetic anhydride, as well as by the Wittig reaction. The product
structure was determined on the basis of their 1H NMR, IR, UV, and mass spectra and quantum-chemical calculations. 2-[2-(9-Anthryl)vinyl]-8-methoxyquinoline
showed luminescence with a quantum yield φ of 0.25, which was considerably higher than that of its 8-hydroxy analog (φ = 0.067). 相似文献
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Summary The partial amino-acid sequence of sturine B has been determined on the basis of a study of the structure of the peptides from its trypsin hydrolysis and a determination of its N- and C-terminal sequence with the aid of leucine aminopeptidase and carboxypeptidases A and B.M. V. Lomonosov Moscow State University. Translated from Khimiya Prirodnykh Soedinenii, No. 6, pp. 778–785, November–December, 1975. 相似文献
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V. D. Selemir A. E. Dubinov B. G. Ptitsyn A. A. Evseenko I. A. Efimova V. A. Letyagin R. K. Nurgaliev N. V. Stepanov K. S. Shilin A. V. Yachnyi 《Technical Physics》2004,49(5):642-646
A high-power microwave oscillator (vircator) is built around an ironless induction linac. The feature of this device is ballistic
focusing of an electron beam in a diode-type system with a concentric spherical cathode and anode. The possibility of the
vircator to generate high-power microwave pulses is demonstrated. 相似文献
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V. A. Arkhipov A. G. Korotkikh V. T. Kuznetsov A. A. Razdobreev I. A. Evseenko 《Russian Journal of Physical Chemistry B, Focus on Physics》2011,5(4):616-624
The results of an experimental study of the regularities of the ignition of composite formulations containing aluminum powders
of different dispersity by a CO2 laser are presented. The dependences of the ignition delay time and thermal mode on the irradiance and the composition of
the composite formulation are obtained. 相似文献
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Wei Wei Veronica I. Evseenko Mikhail V. Khvostov Sergey A. Borisov Tatyana G. Tolstikova Nikolay E. Polyakov Aleksandr V. Dushkin Wenhao Xu Lu Min Weike Su 《Molecules (Basel, Switzerland)》2021,26(6)
Nimesulide (NIM, N-(4-nitro-2-phenoxyphenyl)methanesulfonamide) is a relatively new nonsteroidal anti-inflammatory analgesic drug. It is practically insoluble in water (<0.02 mg/mL). This very poor aqueous solubility of the drug may lead to low bioavailability. The objective of the present study was to investigate the possibility of improving the solubility and the bioavailability of NIM via complexation with polysaccharide arabinogalactan (AG), disodium salt of glycyrrhizic acid (Na2GA), hydroxypropyl-β-cyclodextrin (HP-β-CD) and MgCO3. Solid dispersions (SD) have been prepared using a mechanochemical technique. The physical properties of nimesulide SD in solid state were characterized by differential scanning calorimetry and X-ray diffraction studies. The characteristics of the water solutions which form from the obtained solid dispersions were analyzed by reverse phase and gel permeation HPLC. It was shown that solubility increases for all complexes under investigation. These phenomena are obliged by complexation with auxiliary substances, which was shown by 1H-NMR relaxation methods. The parallel artificial membrane permeability assay (PAMPA) was used for predicting passive intestinal absorption. Results showed that mechanochemically obtained complexes with polysaccharide AG, Na2GA, and HP-β-CD enhanced permeation of NIM across an artificial membrane compared to that of the pure NIM. The complexes were examined for anti-inflammatory activity on a model of histamine edema. The substances were administered per os to CD-1 mice. As a result, it was found that all investigated complexes dose-dependently reduce the degree of inflammation. The best results were obtained for the complexes of NIM with Na2GA and HP-β-CD. In noted case the inflammation can be diminished up to 2-fold at equal doses of NIM. 相似文献
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L. I. Sal’nikov I. I. Brazovskii V. V. Saskovets I. A. Sal’nikova T. I. Evseenko G. V. Makarevich 《High Energy Chemistry》2010,44(3):173-177
A experimental flow unit for investigation of the radiation-catalytic decomposition of gases and liquids over the temperature
range of 50–500°C in a 60Co γ-radiation field was designed and fabricated. The process of radiation-catalytic decomposition of steam in the presence
of solids with different chemical compositions and structures was studied. The effect of the dose rate and the contact time
of the reaction mixture with the solid on the rate of hydrogen formation was revealed. It was shown that the hydrogen formation
efficiency decreases after cessation of irradiation. 相似文献