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IntroductionBreastcancerisoneoftheleadingcausesofprematuredeathinNorthAmericanwomen .Itisanestrogen dependentcancer,1wherevariousantiestrogenhavebeenextensivelyde velopedforitstreatment,suchasbenzothiophene ,proges terone,andthecurrenttamoxifen ,whichprima… 相似文献
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