Monosaccharide osazones are utilized in the spectrophotometric determination of their parent compounds though charge-transfer complexation with two-electron acceptor reagents. The molar combining ratio and the optimum complexation conditions have been studied. The method has been used to analyse for glucose and fructose and in determining blood glucose. 相似文献
An efficient and convenient procedure for the synthesis of novel 6-hydroxy-14-aryl-8H-dibenzo[a,i]xanthene-8,13(14H)-dione derivatives has been developed by one-pot, three-component condensation reaction between 2-hydroxynaphthalene-1,4-dione, aromatic aldehydes and 2,3-naphthalenediol in glacial acetic acid under reflux conditions. This domino reaction implies Knoevenagel condensation, Michael addition, intramolecular cyclization and dehydration. The reaction avoids tedious workup procedure due to the direct precipitation of products from the reaction medium. The notable features of this domino transformation are operational simplicity, clean reaction, easy handling, easy purification process and high yields of the products.
Monosaccharide osazones are utilized in the spectrophotometric determination of their parent compounds through charge transfer complexes (CTC) formation with three-electron acceptor reagents. These acceptors indlude iodine (as -π-acceptor) and chloranil (tetrachloro P-benzoquinone) & TCNE (tetracyano ethylene) as π-acceptors. The presence of two phenylhydrazone moieties in the osazone molecule imparts electron-donating properties toward electron-accepting reagents, yielding spectrophotometrically measurable complexes. However, the reaction of osazone intermediates with TCNE reagent gave tricyanovinyl derivative rather than CTC formation. The above complexes together with their corresponding intermediates were subjected to structure elucidation studies to confirm the results and conclusions obtained. These studies include IR, Raman spectra, H1, C13-NMR, MS, ESR (electron spin resonance spectra) and microanalysis. 相似文献
Chemistry of Heterocyclic Compounds - A facile, convenient, and efficient synthesis of new chromeno[4,3-b]quinoline and chromeno[4,3-b]pyridine derivatives has been accomplished via one-pot... 相似文献
Spectroscopic studies on the reaction of iodine as π-acceptor and chloronil as π-acceptor with oxime intermediates prepared from certain pharmaceutical carbonyl compounds are reported. These compounds include Δ1,4 -3-corticosteroids (prednisone, prednisolone, dexamethasone), Δ4-3-ketosteroids (progesterone, testosterone propinate, nandrolone phenpropionate), griseofulvin, carvone, and menthone. The spectroscopic techniques applied are IR, far IR spectroscopy, H1, C13NMR, mass spectra (MS), fast atom bombardment mass spectra (FABMS), electron spin resonance (ESR) and microanalysis of the reaction products. The structure elucidation studies of these complexes confirmed the charge transfer complex (CTC) formation. 相似文献