Elements in the Sera of Preschool Children Living in Central Taiwan

This study assessed elemental concentrations in the serum of 154 preschool children in central Taiwan via instrumental neutron activation analysis （INAA）. A total of eight elements, Br, C1, Fe, Na, Rb, Sc, Se and Zn of sera for Taiwanese preschool children living at four residential areas： Taichung city, Taichung urban townships and in a remote area inhabited by two groups of aborigines, Atayal and Bunun were determined. Standard reference materials （tomato leaves, NIST-SRM 1570a, and lichen, IAEA-336） were used as quality control standards to crosscheck the accuracy. Residential area, socioeconomic status and gender were shown to significantly influence serum levels of the eight trace elements. Statistical analysis revealed several different gender patterns via the two-tailed student＇s test. A quantified index of agreement （AT） was used to classify these elements. Small AT indicated a close consistency, while large AT indicated a larger fluctuation, or less agreement, such that the correlation between the elements could be interpreted using a series of quantified indices at the serum levels of preschool children.     

出血性中风患者头发微量元素铬硒锰镁锌铜铁测定分析

检测了１９３例急性脑出血和１５例老年性蛛网膜下腔出血患者头发中铬，硒，锰，镁，锌，铜，铁含量，结果表明，出血性中风患者发铬，硒，锰，镁，锌含量均降低，铜升高，铁正常。讨论了该病与微量元素的关系。     

基于UPLC-oaTOF-MS的糖尿病及糖尿病肾病的代谢组学研究

以糖尿病患者、糖尿病肾病患者和正常人的血清为研究对象, 采用超高效液相色谱-飞行时间质谱建立其代谢指纹图谱, 并结合主成分分析进行模式识别, 实现患者和正常人的区分, 并试图发现潜在的标志物.