Synthesis,Crystal Structure and Antitumor Activity of a Ca(Ⅱ) Coordination Polymer Based on 4-Acetylphenoxyacetate Ligands

A novel Ca(Ⅱ) coordination polymer,[Ca L₂(H₂O)₂]_n (1,HL=4-acetylphenoxyacetic acid) has been synthesized with 4-acetylphenoxyacetic acid,Ca(ClO_4)₂·4H₂O and Na OH as raw materials.Complex 1 was characterized by elemental analysis and single-crystal X-ray diffraction analysis.The results show that the Ca(Ⅱ)ion is eight-coordinated in a distorted triangular dodecahedral geometric configuration with six carboxylate Oatoms of four L ligands and two O atoms of two coordinated water molecules.Complex 1 forms a one-dimensional chained structure by the bridging effect of carboxylate O atoms.The antitumor activity of HLligand and complex 1 has also been investigated.