Syntheses,Structures and Antitumor Activities of Tri(o-bromobenzyl)tin Diethyldithiocarbamate and Tri(m-fluorobenzyl)tin Pyrrolidine Dithiocarbamate

Tri(o-bromobenzyl)tin diethyldithiocarbamate(1) and tri(m-fluorobenzyl)tin pyrrolidine dithiocarbamate(2) have been synthesized and characterized by elemental analysis, IR spectroscopy, NMR(~1 H, ¹³C and ¹¹⁹Sn), thermogravimetric analysis and single-crystal X-ray diffraction. The two complexes crystallize in the triclinic system space group P1. For complex 1, a = 0.9770(1), b = 1.1011(1), c = 1.4583(1) nm, α = 78.431(1)°, β = 86.307(1)°, γ = 69.712(1)°, V = 1.4417(2) nm^3, Z = 2, Dc = 1.790 g/cm^3, m(Mo Kα) = 52.04 cm–1, F(000) = 756, R = 0.0434 and wR = 0.0593. For complex 2, a = 0.7055(1), b = 1.3349(3), c = 1.3782(3) nm, α = 89.216(2)°, β = 82.044(2)°, γ = 84.637(2)°, V = 1.2799(5) nm^3, Z = 2, Dc = 1.537 g/cm^3, m(Mo Kα) = 11.98 cm^–1, F(000) = 596, R = 0.0313 and wR = 0.0333. The two complexes represent mononuclear structures with five-coordinated [SnC3S2] cores forming a distorted trigonal bipyramid. The quantum chemical calculations of 1 and 2 have been investigated. The antitumor activity shows that 1 and 2 have higher activities than cisplatinum against Colo205, HepG2, MCF-7, Hela and H460 cell line in vitro.     

滨海公共空间声环境感知评价及影响因素*

滨海公共空间是滨海城市人居环境的重要组成部分,其声环境质量是影响公共空间环境体验的关键因素。本研究以青岛沿海岸线四类滨海公共空间（步道类、广场类、公园类、沙滩类）的声环境为对象,通过问卷调查和实地测量探索滨海公共空间声环境的特征、感知评价及其影响因素。结果表明：（1）滨海公共空间当前环境噪声水平基本不超过国家标准限值55dB(A) ,各类空间声环境客观特征显著不同：公园噪声水平最低,自然声源丰富;广场噪声水平最高,各种城市噪声较多;步道噪声水平较低,但受到交通噪声的影响;沙滩噪声水平较高,但以中低频的海浪声为主,比较稳定。（2）各类滨海公共空间的声源感知以自然声为主,但是广场的自然声源感知较少。此外,声环境的愉悦感评价普遍较高,但在事件感、吵闹度和总体满意度评价上具有显著差异：沙滩声环境总体评价最好,其次是公园,广场和步道的声环境则亟待改善。（3）交通噪声和最大声级Lmax对声环境的负面影响最为显著,此外受访者年龄也是影响滨海公共空间声环境感知评价的关键因素。研究结论可以为滨海公共空间声环境的优化设计提供理论依据。