Brønsted Acidic Ionic Liquids: New,Efficient, and Green Promoter System for the Synthesis of 4(3H)-Quinazolinones

A simple, inexpensive, and efficient new synthesis of 4(3H)-quinazolinones from the reaction of 2-aminobenzamide with aroyl chlorides in the presence of two new halogen-free Brønsted acidic ionic liquids, 3-methyl-1-(4-sulfonic acid)butylimidazolium hydrogen sulfate [(CH₂)₄SO₃HMIM][HSO₄] and 1-(4-sulfonic acid) butylpyridinium hydrogen sulfate [(CH₂)₄SO₃HPY][HSO₄], green and reusable catalysts, with excellent product yields under solvent-free conditions is reported. The products could be separated simply from the catalyst, and the catalyst could be recycled without noticeably decreasing the catalytic activity.     

Brønsted Acidic Ionic Liquids as Efficient Catalysts for the Synthesis of Amidoalkyl Naphthols

A simple, clean, and environmentally benign three-component process for the synthesis of amidoalkyl naphthols using Brønsted acidic ionic liquids as efficient catalysts in solution and under solvent-free conditions is described.     

7-Deazapurines:Synthesis of new pyrrolo[2,3d]pyrimidin-4-onescatalyzed by a Brφnsted-acidic ionic liquid as a green and reusable catalyst

<正>Some new 2-aryl-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-ones have been prepared through cyclocondensation of 2-amino 1H-pyrrole-3-carboxamides with aromatic aldehydes followed by air oxidation in the presence of 3-methyl-1-(4-sulfonic acid)butylimidazolium hydrogen sulfate[(CH_2)_4SO_3HMIM][HSO_4],a Br(?)nsted-acidic ionic liquid,as a green and reusable catalyst in solvent-free conditions.     

Highly efficient, one-pot, solvent-free synthesis of 2,4,6-triarylpyridines using a Br?nsted-acidic ionic liquid as reusable catalyst

Abstract  

A simple, efficient, and green method for synthesis of 2,4,6-triarylpyridines by one-pot three-component reaction of acetophenones, aryl aldehydes, and ammonium acetate using 3-methyl-1-(4-sulfonylbutyl)imidazolium hydrogen sulfate [HO₃S(CH₂)₄MIM][HSO₄], a Br?nsted-acidic ionic liquid, as an effective and reusable catalyst under solvent-free conditions is described. This method has several advantages, for example simple procedure with an easy work-up, shorter reaction times, and high yields.     

Carbon-Based Solid Acid as An Efficient and Reusable Catalyst for One-Pot Synthesis of Tetrasubstituted Imidazoles under Solvent-Free Conditions

Carbon‐based solid acid catalyst was found to be highly efficient, eco‐friendly and recyclable heterogeneous catalyst for the multicomponent reaction of benzil, aromatic aldehyde, primary amine and ammonium acetate, giving rise to 1,2,4,5‐tetrasubstituted imidazoles in good to excellent yields. The present methodology offers several advantages, such as high yields, short reaction time, mild reaction condition and a recyclable catalyst with a very easy work up.     

New route to 2-arylthieno[2,3-d]pyrimidin-4(3H)-ones and isolation of the unoxidized intermediates

Abstract  A new route to the synthesis of 2-arylthieno[2,3-d]pyrimidin-4(3H)-ones has been developed through heterocyclization of 2-amino-4,5-dimethylthiophene-3-carboxamide with aromatic aldehydes in boiling glacial acetic acid followed by air oxidation. The unoxidized intermediates, 2-aryl-2,3-dihydrothieno[2,3-d]pyrimidin-4(1H)-ones, are isolated when the reactions are carried out either at room temperature or under a nitrogen atmosphere. Graphical Abstract        

A new route to the synthesis of thieno[2,3-d]pyrimidin-4（3H）-one derivatives catalyzed by 12-tungstophosphoric acid （H3PW12040）

Heteropoly acid H3PW12040 （PW） has been used as an effective catalyst for the synthesis of thieno[2,3-d]pyrimidin-4（3H）-one derivatives. The present methodology offers several advantages, such as high yields, short reaction times, mild reaction condition and a recyclable catalyst with a very easy work up.     

Br?nsted-acidic ionic liquid [HO3S(CH2)4MIM][HSO4] as efficient and reusable catalyst for one-pot synthesis of β-acetamido ketones

Abstract  

Efficient and convenient synthesis of β-acetamido ketones has been achieved by one-pot reaction of acetophenone, aryl aldehydes, acetyl chloride, and acetonitrile in the presence of 3-methyl-1-(4-sulfonylbutyl)imidazolium hydrogensulfate [HO₃S(CH₂)₄MIM][HSO₄], a Br?nsted-acidic ionic liquid, as a green and reusable catalyst in solvent-free media at room temperature. The catalyst could be recycled and reused without noticeable decrease in catalytic activity.     

Green,One-Pot,Solvent-Free Synthesis of 1,2,4,5-Tetrasubstituted Imidazoles Using a Brønsted Acidic Ionic Liquid as Novel and Reusable Catalyst

3-Methyl-1-(4-sulfonic acid)butylimidazolium hydrogen sulfate [(CH₂)₄SO₃HMIM][HSO₄], a Brønsted acidic ionic liquid, has been used as an efficient, green, and reusable catalyst for the synthesis of 1,2,4,5-tetrasubstituted imidazoles using benzil, an aromatic aldehyde, and a primary amine in the presence of ammonium acetate under solvent-free conditions. The catalyst could be recycled and reused several times without noticeably decreasing the catalytic activity.