排序方式: 共有16条查询结果,搜索用时 15 毫秒
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Ersan Ronak Haj Alagoz Mehmet Abdullah Ertan-Bolelli Tugba Duran Nizami Burmaoglu Serdar Algul Oztekin 《Molecular diversity》2021,25(4):2247-2259
Molecular Diversity - In the present work, a series of bisbenzazole derivatives were designed and synthesized as antiproliferative agents. The antiproliferative activity of these compounds was... 相似文献
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Ersan Altun Vasco Heredia Ertan Pamuklar Mauricio Zapparoli Richard C. Semelka 《Magnetic resonance imaging》2009,27(9):1198-1207
Purpose
To determine the feasibility of post-gadolinium three-dimensional gradient-echo (3D-GE) sequence for the evaluation of the pulmonary arterial vasculature in patients with suspected pulmonary embolism (PE) and in patients with a variety of other disease processes.Materials and Methods
Twenty-six consecutive patients (18 females, 8 males; mean age±S.D., 46.6±21.1 years) who underwent chest magnetic resonance imaging (MRI) including post-gadolinium 3D-GE sequence for the evaluation of PE (Group A, n=13) and a variety of other disease processes (Group B, n=13) were included in the study. Post-gadolinium 3D-GE MR sequences were retrospectively, independently and blindly evaluated by two reviewers for the image quality of pulmonary arterial vasculature, and findings of PE and other disease processes. Clinical and imaging follow-up data for all patients were obtained. Interobserver agreement was calculated by kappa statistics.Results
All central and lobar pulmonary arteries, 71.4–89.6% of segmental arteries and 46.7–52.7% of subsegmental arterial units in both groups were visualized with sufficient diagnostic image quality on post-gadolinium 3D-GE sequences. PE involving lobar and segmental arteries was diagnosed in two patients in each group. Other disease processes including pneumonia, lung nodules, superior vena cava stenosis, lung metastases, chronic lymphocytic leukemia and aortic aneurysm were detected in 10 of 26 patients. There was good to excellent interobserver agreement (0.73 to 1.00) for all findings.Conclusion
Post-gadolinium 3D-GE sequence may be an alternative technique for the visualization of central, lobar and segmental arteries, and may diagnose PE and other pathologies involving the chest in different patient populations. 相似文献4.
Jorge Elias Jr. Ersan Altun Steven Zacks Diane M. Armao John T. Woosley Richard C. Semelka 《Magnetic resonance imaging》2009,27(7):976-987
Purpose
To evaluate magnetic resonance imaging (MRI) findings of nonalcoholic steatohepatitis (NASH) and to determine the correlation of MRI findings with histopathology and Mayo End-Stage Liver Disease (MELD) score.Materials and Methods
Thirty patients (18 males, 12 females; mean age: 57±8.9 years; age range: 35–71 years) with histopathologically proven NASH who underwent MRI examinations between January 2001 and October 2005 were included in the study. Two radiologists retrospectively reviewed all magnetic resonance (MR) examinations in consensus to evaluate the presence and extent of predetermined findings of NASH including liver steatosis, early patchy liver enhancement indicating inflammation and liver fibrosis. The findings detected on MRI were correlated and compared to histopathological findings and MELD score by using nonparametric Spearman correlation coefficient and Kruskal–Wallis analysis of variance.Results
Liver steatosis was observed in 10 of 30 patients; early patchy liver enhancement, in 8 of 30 patients and liver fibrosis in 19 of 30 patients on MR images. Liver fibrosis was reticular in all these patients. There were statistically significant moderate correlations between MRI findings of liver steatosis and histopathologic grades of steatosis (r=0.43; P<.05), and between MRI findings of fibrosis and histopathologic stages of fibrosis (r=0.61; P<.001). Early patchy enhancement did not demonstrate statistically significant correlation with inflammation (P=.28). There was no statistically significant overall correlation between MRI findings of NASH and MELD score.Conclusion
MRI findings of liver steatosis and fibrosis in NASH showed moderate correlations with histopathologic grades of steatosis and stages of fibrosis, but MRI findings of NASH did not demonstrate any significant correlations with MELD score. 相似文献5.
In this paper, we presented a stable two-dimensional ruthenium dioxide monolayer by using first-principles calculations within density functional theory. In contrast to ordinary hexagonal and octahedral structures of metal dichalcogenides, RuO2 is stable in the distorted phase of the structure as a result of occurring charge density wave. A comprehensive analysis including the calculation of vibration frequencies, mechanical properties, and ab initio molecular dynamics at 300?K affirms that RuO2 monolayer structure is stable dynamically and thermally and convenient for applications at room temperature. We also investigated the electronic and optical properties of RuO2 and it is found that RuO2 has of 0.74?eV band gap which is in the infrared region and very suitable for infrared detectors. 相似文献
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Computational Materials Chemistry at the Nanoscale 总被引:1,自引:0,他引:1
Çağın Tahir Che Jianwei Qi Yue Zhou Yanhua Demiralp Ersan Gao Guanghua Goddard William A. 《Journal of nanoparticle research》1999,1(1):51-69
In order to illustrate how atomistic modeling is being used to determine the structure, physical, and chemical properties of materials at the nanoscale, we present here the results of molecular dynamics (MD) simulations on nanoscale assemblies of such materials as carbon nanotubes, diamond surfaces, metal alloy nanowires, and ceramics. We also include here the results of nonequilibrium MD simulations on the nanorheology of a monolayer of wear inhibitor self-assembled on two metal oxide surfaces, separated by hexadecane lubricant, and subjected to steady state shear.We also present recent developments in force fields (FF) required to describe bond breaking and phase transformations in such systems. We apply these to study of plasticity in metal alloy nanowires where we find that depending on the strain rate, the wire may deform plastically (forming twins), neck and fracture, or transition to the amorphous phase. 相似文献
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Haydar Uncu Hakan Erkol Ersan Demiralp Haluk Beker 《Central European Journal of Physics》2005,3(2):303-323
We have studied bound states of the Schrödinger equation for a linear potential together with any finite number (P) of Dirac delta functions. Forx<-0, the potential is given as where 0<f; 0<x 1<x 2<...<x P , theσ i are arbitrary real numbers, and the potential is infinite forx<0.
相似文献
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Ersan Demiralp 《Czechoslovak Journal of Physics》2005,55(9):1081-1084
We have investigated bound state solutions of the Schrodinger equation for one-dimensional harmonic oscillator potential together
with even number of Dirac delta functions. These point interactions are located at symmetric points x = x
i
and x = −x
i
(i = 1, 2,..., N) and they have complex conjugate strengths
and
, respectively. We present explicit forms of eigenfunctions and an algebraic eigenvalue equation and numerical solutions for
this
-symmetric Hamiltonian.
Presented at the 3rd International Workshop “Pseudo-Hermitian Hamiltonians in Quantum Physics”, Istanbul, Turkey, June 20–22,
2005. 相似文献
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Jose A. Goncalves Neto Ersan Altun Georgeta Vaidean Mohamed Elazzazi Jeffrey Troy Sudha Ramachandran Richard C. Semelka 《Magnetic resonance imaging》2009