Physicochemical properties and bio-interfacial interactions of surface modified PDLLA-PAMAM linear dendritic block copolymers

Here, we demonstrate the applicability of self-assembling linear-dendritic block copolymers (LDBCs) and their nanoaggregates possessing varied surfaces as therapeutic nanocarriers. These LDBCs are comprised of a hydrophobic, linear polyester chemically coupled to a hydrophilic dendron polyamidoamine (PAMAM)—the latter of which acts as the surface of the self-assembled nanoaggregate in aqueous media. To better understand how surface charge density affects the overall operability of these nanomaterials, we modified the nanoaggregate surface to yield cationic (NH₃⁺), neutral (OH), and anionic (COO⁻) surfaces. The effect of these modifications on the physicochemical properties (i.e., size, morphology, and surface charge density), colloidal stability, and cellular uptake mechanism of the polymeric nanocarrier were investigated. This comparative study demonstrates the viability of nanoaggregates formed from PDLLA-PAMAM LDBCs to serve as nanocarriers for applications in drug delivery.     

Electromechanical properties of Pb<Subscript>3</Subscript>Ga<Subscript>2</Subscript>Ge<Subscript>4</Subscript>O<Subscript>14</Subscript> piezoelectric crystals grown from solution in a melt

Single crystals of lead gallium germanate Pb₃Ga₂Ge₄O₁₄ are grown from their own solution melts. The propagation of bulk acoustic waves is investigated, and the elastic, piezoelectric, and dielectric constants are calculated. The temperature dependences of the dielectric constants of this compound are analyzed.     

Orders of Indescribable Sets

We extract some properties of Mahlo’s operation and show that some other very natural operations share these properties. The weakly compact sets form a similar hierarchy as the stationary sets. The height of this hierarchy is a large cardinal property connected to saturation properties of the weakly compact ideal.     

Spin-transfer switching in MgO magnetic tunnel junction nanostructures

Spin-transfer driven switching was observed in MgO based magnetic tunnelling junctions (MTJ) with tunnelling magnetoresistance ratio of up to 160% and the average intrinsic switching current density (J_c0) down to 2 MA/cm², which are the best known results reported in spin-transfer switched MTJ nanostructures. Based on a comparison of results both from MgO and AlO_x MTJs, further switching current decrease via MgO dual structures with two pinned layers is discussed.     

Deacetalisation-bicyclisation routes to novel polycyclic heterocycles using stannous chloride dihydrate

The stannous chloride dihydrate-mediated deprotection-bicyclisation of a range of amides possessing a pendant acetal group is reported. These mild reaction conditions have been used to prepare a number of ring-fused heterocyclic compounds, some in enantiomerically pure form, which should be of interest both in their own right and as building blocks for the production of more complex target molecules.     

Property (<Emphasis Type="Italic">T</Emphasis>) and rigidity for actions on Banach spaces

We study property (T) and the fixed-point property for actions on L ^p and other Banach spaces. We show that property (T) holds when L ² is replaced by L ^p (and even a subspace/quotient of L ^p ), and that in fact it is independent of 1≤p<∞. We show that the fixed-point property for L ^p follows from property (T) when 1<p< 2+ε. For simple Lie groups and their lattices, we prove that the fixed-point property for L ^p holds for any 1< p<∞ if and only if the rank is at least two. Finally, we obtain a superrigidity result for actions of irreducible lattices in products of general groups on superreflexive spaces. Bader partially supported by ISF grant 100146; Furman partially supported by NSF grants DMS-0094245 and DMS-0604611; Gelander partially supported by NSF grant DMS-0404557 and BSF grant 2004010; Monod partially supported by FNS (CH) and NSF (US).     

Magnetometer based on a pair of symmetric transitions in the 87Rb hyperfine structure

A new version of the fast optically pumped magnetometer, an optically pumped balanced quantum magnetometer, built around a pair of symmetric transitions in the hyperfine structure of the ⁸⁷Rb ground state is implemented for the first time. The noise-limited sensitivity of the prototype in terms of the variance is 6 pT for a measurement time of 0.1 s. The basic advantages of the new magnetometer are the absence of dead zones when it changes orientation relative to the magnetic field and an extremely low sensitivity to the drift of pumping parameters.     

Pyroelectric effect in lead-magnoniobate-based solid solutions

A coordinated study of the dielectric, electrostriction, and pyroelectric properties of the lead-magnoniobate-based ceramic solid solutions 0.9PbMg_1/3Nb_2/3O₃-0.1PbTiO₃ and 0.55PbMg_1/3Nb_2/3O₃-0.45PbSc_1/2Nb_1/2O₃ conducted at the relaxor transition temperatures is reported. Electromechanical coupling stimulated by the giant electrostriction effect is shown to play an essential part in the pyroelectric effect.     

Lorentz-Covariant Loop Quantum Gravity

We review the Lorentz-covariant approach to loop quantum gravity. This approach solves the Immirzi parameter problem occurring in the standard loop approach based on the SU(2) gauge group. We show that there exists a unique loop quantization preserving all the classical symmetries at the quantum level and that the results obtained with it, such as the area operator spectrum, are independent of the Immirzi parameter. The standard SU(2) approach violates the diffeomorphism invariance and is therefore an incorrect quantization of gravity.