Micellar Liquid Chromatography Study of Quantitative Retention–Activity Relationships for Antihypertensive Drugs

Use of micellar mobile phases in reversed-phase liquid chromatography (RPLC) results in hydrophobic and electrostatic sites for interaction. Modified stationary phases in micellar liquid chromatography (MLC) are structurally similar to biomembranes. To confirm this we focused on the effects of the type and concentration of surfactant (Brij 35, SDS, and CTAB) and mobile phase pH on the retention of antihypertensive drugs on modified C₁₈ stationary phases. Quantitative retention-activity relationships are proposed for the drugs and the different surfactants and compared with those obtained using aqueous–organic mobile phases. Finally, a correlation was obtained between the logarithm of retention factors (log k) and the toxicity (LD₅₀) of antihypertensive drugs. Revised: 14 September 2005 and 4 April 2006     

Improvement of window thermal performance using aerogel insulation film for building energy saving

In buildings, windows have a major influence on space heating demand and indoor environment both with respect to climate and daylight. To reduce the window coefficient of the overall heat transmission, we use aerogel. Aerogels have a high surface area, low density, open pore structure, and excellent insulation properties. We mixed pressure sensitive adhesive and aerogel (10, 15, and 20 mass%) using a homogenizer. A mixture of the adhesives and silica aerogels attached film can reduce thermal conductivity. Silica aerogels are characterized by a surface area analyzer (BET), a Fourier transform infrared spectrometer, a thermogravimetry (TG) analyzer, and probe tack method. Thermal conductivity was measured by a TCi thermal conductivity analyzer.     

A Highly Sensitive Amperometric Galactose Biosensor Based on Graphene-doped Sol-gel-derived Titania-Nafion Composite Films

A highly sensitive amperometric galactose biosensor was developed by encapsulating galactose oxidase within the graphene-doped sol-gel titania-Nafion composite film on platinized glassy carbon electrode. Due to the combined electrocatalytic activity of graphene and Pt NPs on the electrode towards hydrogen peroxide as well as the mesoporous nature of the titania-Nafion composite, the present galactose biosensor exhibited relatively fast response time under 2 s, high sensitivity of 40.6 mAM⁻¹cm⁻², and wide dynamic range over three orders of magnitude with a detection limit of 3.78×10⁻⁶ M (S/N=3). In addition, the biocompatible composite in the biosensor secures excellent long-term stability.     

Preparation of thermal-enhanced epoxy resin adhesive with organic PCM for applying wood flooring

Epoxy resins are well-known materials that show beneficial properties, such as high tensile strength and modulus, good adhesive properties, low cost, and ease of processing and environmental advantages. However, epoxy resin adhesive has no characteristic of thermal storage. Latent heat storage is one of the favorable kinds of thermal energy storage methods considered for energy saving and thermal efficiency in various fields, such as solar air conditioning systems and buildings. So we prepared thermal-enhanced epoxy resin adhesive by using PCM. This paper addresses the effects of n-hexadecane and sodium lauryl sulfate on the thermal properties and chemical properties of epoxy resin adhesive and HEAC, using differential scanning calorimetry, thermal gravimetric analysis, and Fourier transform-infrared spectroscopy. Also, we evaluated the applicability of composite epoxy resin adhesive to wood-based flooring using n-hexadecane, through measurement of bonding strength from universal testing machine analysis.     

Direct Regio‐ and Diastereoselective Synthesis of δ‐Lactams from Acrylamides and Unactivated Alkenes Initiated by RhIII‐Catalyzed C−H Activation

We report a Rh^III‐catalyzed regio‐ and diastereoselective synthesis of δ‐lactams from readily available acrylamide derivatives and unactivated alkenes. The reaction provides a rapid route to a diverse set of δ‐lactams in good yield and stereoselectivity, which serve as useful building blocks for substituted piperidines. The regioselectivity of the reaction with unactivated terminal alkene is significantly improved by using Cp^t ligand on the Rh^III catalyst. The synthetic utility of the reaction is demonstrated by the preparation of a potential drug candidate containing a trisubstituted piperidine moiety. Mechanistic studies show that the reversibility of the C?H activation depends on the choice of Cp ligand on the Rh^III catalyst. The irreversible C?H activation is observed and becomes turnover‐limiting with [Cp^tRhCl₂]₂ as catalyst.     

A novel method for separating Cs<Superscript>+</Superscript> from liquid radioactive waste using ionic liquids and a selective extractant

Selective separation of Cs ⁺ from liquid radioactive waste by “precipitation” was observed in a hydrophobic ionic liquid containing the Cs ⁺ -selective extractant dicyclohexano-18-crown-6. The precipitate was formed by the cation exchange mechanism, which simplified the treatment of Cs ⁺ after extraction. Solid–liquid extraction is a more economical extraction system than liquid–liquid extraction because it uses smaller quantities of ionic liquids. This work showed the possibility of developing a new method for removing Cs ⁺ from liquid radioactive waste using solid–liquid phase separation instead of the conventional liquid–liquid separation in an ionic liquid extraction system.     

Fabrication of Ni-P/palygorskite core-shell linear powder via electroless deposition

Palygorskite is a kind of hydrated magnesium aluminium silicate clay mineral. A novel linear core-shell structured Ni-P coated micro-fiber palygorskite (MFP) was fabricated via an electroless (EL) plating process in an alkaline bath. The composition, morphology and structure of the as-prepared products were characterized by the techniques such as powder X-ray diffraction (XRD), energy-dispersive X-ray spectrum (EDS), scanning electron microscopy (SEM) and transmission electron microscope (TEM). It was observed that the size and morphology of Ni-P coated MFPs were altered by depositing temperature and time. The as-prepared Ni-P coated MFPs showed good conductivity. To the best of our knowledge, the Ni-P coated MFPs have not been reported before. And this fabrication process might also apply in preparing other metal coated MFPs such as silver, copper and palladium.