Acid-catalyzed intramolecular cyclization of N-(4,4-diethoxybutyl)sulfonamides as a novel approach to the 1-sulfonyl-2-arylpyrrolidines

Herein we report our studies on the acid-catalyzed cyclisation of N-(4,4-diethoxybutyl)sulfonamides at the presence of polyatomic phenols as an efficient one-pot approach to the synthesis of 1-sulfonyl-2-arylpyrrolidines from the acyclic precursors.     

Synthesis of new phosphorylated analogs of nucleotides containing adenine and ethylidene-1,1-bisphosphoryl moieties

Reaction of adenine and 9-[2-(1,3-dioxolan-2-yl)ethyl]-9H-purine-6-amine with ethylidene-1,1-bisphosphonates resulted in the formation of new purine bases containing ethylidene-1,1-bisphosphoryl groups.

     

Synthesis of Alkylphosphoryl-Containing 4(5)-Arylimidazolin-2-ones

Russian Journal of General Chemistry - The acid-catalyzed reaction of {2-[1-(2,2-dimethoxyethyl)-3-(phenylcarboxamido)]ethyl}phosphonate or diethyl...     

Methods for the synthesis of 1H-pyrazolo[3,4-b]pyridine derivatives

This review covers and summarizes comprehensive data reported within the period from 2017 to 2021 on the synthetic strategies and approaches to 1H-pyrazolo[3,4-b]pyridine derivatives. Methods for the synthesis are systematized according to the method to assemble the pyrazolopyridine system, whereas their advantages and drawbacks are considered.

     

Reaction of Sesamol with N-(3,3-Diethoxypropyl)ureas. Synthesis of Diarylpropanes

Russian Journal of Organic Chemistry - An efficient procedure has been developed for the synthesis diarylpropanes containing an urea fragment by acid-catalyzed reaction of...     

Synthesis of new nucleoside analogs containing amino bisphosphonic groups

Adenosine derivatives containing a 2,2-bis(diethoxyphosphoryl)ethyl or 2,2-diphosphonoethyl group on the amino nitrogen atom were synthesized for the first time by reaction of 5′-chloro-5′-deoxy- and 5′-hydroxy-2′,3′-isopropylideneadenosine with tetraethyl ethene-1,1-diylbis(phosphonate) or tetrakis(trimethylsilyl) ethene-1,1-diylbis(phosphonate).     

Synthesis of 2-arylpyrrolidines by reaction of γ-ureidoacetals with benzene-1,3,5-triol

New 2,2′-(2,4,6-trihydroxybenzene-1,3-diyl)dipyrrolidine derivatives have been synthesized by reaction of benzene-1,3,5-triol (phloroglucinol) with γ-ureidoacetals in the presence of trifluoroacetic acid as catalyst.     

Synthesis of 2-Arylpyrrolidines by Reactions of 3-Arylidene-1-pyrrolines with Phenols

Russian Journal of General Chemistry - The reaction of 3-arylidene-1-pyrrolines with phenols yielded 2-arylpyrrolidines. The proposed method makes it possible to obtain pyrrolidines containing a...     

Synthesis of novel 2-arylpyrrolidines by the reaction of 1-(4,4-diethoxybutyl)urea with resorcinols

Reaction of 1-(4,4-diethoxybutyl)urea with resorcinol, 2-methylresorcinol and pyrogallol in chloroform in the presence of trifluoroacetic acid affords new 2,2′-(1,3-phenylene)-bis(pyrrolidine-1-carboxamides).