全文获取类型
收费全文 | 2822篇 |
免费 | 118篇 |
国内免费 | 19篇 |
专业分类
化学 | 1996篇 |
晶体学 | 17篇 |
力学 | 21篇 |
数学 | 382篇 |
物理学 | 543篇 |
出版年
2023年 | 18篇 |
2022年 | 20篇 |
2021年 | 55篇 |
2020年 | 57篇 |
2019年 | 70篇 |
2018年 | 57篇 |
2017年 | 58篇 |
2016年 | 119篇 |
2015年 | 95篇 |
2014年 | 116篇 |
2013年 | 196篇 |
2012年 | 182篇 |
2011年 | 231篇 |
2010年 | 139篇 |
2009年 | 116篇 |
2008年 | 176篇 |
2007年 | 154篇 |
2006年 | 146篇 |
2005年 | 102篇 |
2004年 | 104篇 |
2003年 | 75篇 |
2002年 | 80篇 |
2001年 | 35篇 |
2000年 | 29篇 |
1999年 | 29篇 |
1998年 | 33篇 |
1997年 | 23篇 |
1996年 | 29篇 |
1995年 | 19篇 |
1994年 | 11篇 |
1993年 | 22篇 |
1992年 | 18篇 |
1991年 | 16篇 |
1990年 | 21篇 |
1989年 | 10篇 |
1988年 | 15篇 |
1987年 | 21篇 |
1986年 | 10篇 |
1985年 | 15篇 |
1984年 | 10篇 |
1983年 | 11篇 |
1982年 | 11篇 |
1980年 | 12篇 |
1977年 | 14篇 |
1976年 | 11篇 |
1975年 | 11篇 |
1968年 | 10篇 |
1966年 | 10篇 |
1957年 | 8篇 |
1955年 | 9篇 |
排序方式: 共有2959条查询结果,搜索用时 78 毫秒
1.
Tomáš Hložek Martin Štícha Miroslava Bursová Ivan Jelínek Petr Tůma Radomír Čabala 《Electrophoresis》2020,41(18-19):1564-1567
Riociguat is novel antihypertensive drug for treatment of pulmonary hypertension. As such, it is still being tested in many clinical and pharmacokinetic trials. Existing methods that determine serum riociguat and desmethylriociguat (DMR) are based solely on liquid chromatography with mass spectrometry. Therefore, we present a novel capillary electrophoresis with mass spectrometry method (CE-MS) for their determination in human serum as alternative method for ongoing trials. Complete resolution of both analytes was achieved by means of pH optimization of ammonium formate background electrolytes that are fully compatible with ESI/MS detection. Simple liquid-liquid extraction was used as sample pretreatment. The calibration dependence of the method was linear (in the range of 10–1000 ng/mL), with adequate accuracy (90.1–114.9%) and precision (13.4%). LOD and LOQ were arbitrarily set at 10 ng/mL for both analytes. Clinical applicability was validated using serum samples from patients treated with riociguat in pharmacokinetic study and the results corresponded with reference HPLC-MS/MS values. Capillary electrophoresis proved to be sensitive and selective tool for the analysis of riociguat and DMR. 相似文献
2.
Nováková Kateřina Hrdlička Vojtěch Navrátil Tomáš Vyskočil Vlastimil Barek Jiří 《Monatshefte für Chemie / Chemical Monthly》2015,146(5):761-769
Monatshefte für Chemie - Chemical Monthly - The voltammetric behavior of 5-nitroindazole was investigated at polished (p-AgSAE) and at mercury meniscus-modified (m-AgSAE) silver solid amalgam... 相似文献
3.
4.
5.
Bajdik J. Pintye-Hódi K. Novák Cs. Kelemen A. Regdon G. Erős I. 《Journal of Thermal Analysis and Calorimetry》2002,68(2):613-627
The extents of the protective effects of coating films on the surface of crystals were determined. Three different samples
were made with different quantities of coating fluid (Sepifilm LP 010 in 10% aqueous solution). Since the atomizing rate was
constant, the coating time increased in parallel with the volume of coating fluid applied. The direct measurement of film
thickness and smoothness is very difficult, and therefore indirect methods were used. Dimenhydrinate was chosen as model drug;
this is a heat-sensitive antihistamine with a low melting point. This temperature can be reached during the tableting process.
The behaviour of samples on exposure to heat was examined by differential scanning calorimetry. The water uptakes of the samples
were determined with an Enslin apparatus. Plasticity was studied with an instrumented tablet machine. These indirect methods
(thermal conductivity, water uptake and plasticity measurements) revealed connections between the results of the various experiments.
An overlong coating time decreased the protective effect of the coating film.
This revised version was published online in August 2006 with corrections to the Cover Date. 相似文献
6.
We predict ultraslow collapse of “tubular image states” (TIS) on material surfaces. TIS are bound Rydberg-like electronic states formed at large distances (∼30 nm) from the surfaces of suspended circularly-symmetric nanowires, such as metallic C nanotubes. The states are formed in potential wells, resulting from a combination of the TIS-electron attraction to image charges in the nanotube and its centrifugal repulsion, caused by spinning around the tube. We demonstrate that TIS can collapse on the tube surface by passing their angular momentum l to circularly polarized flexural phonons excited in the tube. Our analysis shows that for highly detached TIS with l ? 6 the relaxation lifetimes are of the order of 10 ns-1 μs, while for l < 6 these lifetimes are reduced by several orders of magnitude. 相似文献
7.
V. Petržílka 《Czechoslovak Journal of Physics》1997,47(2):183-196
Test particle motion and acceleration has been explored in strong radio frequency (RF) fields, for which quasilinear ponderomotive force approximation is not valid. By nonlinear acceleration in spatially varying wave amplitude of RF travelling wave, electrons may be accelerated to time averaged velocities significantly larger than the RF wave phase velocity, and than the boundary plasma thermal velocity, in RF fields of several Volts per centimeter at wave frequency of 7 MHz. It is also demonstrated that even weak spatial gradients, much weaker than those expected in experiments, of the RF wave field amplitude, have significant consequences for the particle motion. Estimates are presented of the total energy transferred from the near antenna RF field to the plasma due to the nonlinear electron acceleration effects. 相似文献
8.
Pavla Fialová Inmaculada Robina Petr Sedmera Lucie Petrásková-Hušáková 《Tetrahedron letters》2005,46(50):8715-8718
Glycosyl azides are new efficient donors for glycosidases. Their high water solubility facilitates transglycosylations with comparable or better yields than common O-glycosides. The azido group totally changes the β-GalNAc-ase/β-GlcNAc-ase ratio in β-N-acetylhexosaminidases (from the usual 0.3-1.0 to <0.01), contrary to all known aglycons. 相似文献
9.
J. Mlynár J. Ongena The EFDA JET Contributions I. Duran M. Hron R. Pánek V. Petržílka F. Žáček 《Czechoslovak Journal of Physics》2004,54(3):C28
JET (Joint European Torus) is the largest tokamak in the world and the only fusion facility able to operate with Tritium, the fusion fuel, and Beryllium, the ITER first wall material. JET also features the most complete remote handling equipment for invessel maintenance. As a multinational research center, JET provides logistic experience in preparing for operation of the global facility, tokamak ITER.Experiments on JET are focused on ITER-relevant studies, in particular on detailing the operational scenarios (EL My H-modes and advanced regimes), on enhancing the heating systems, on developing diagnostics for burning plasmas etc. Pioneering real-time control techniques have been implemented that maximize performance and minimize internal disturbances of JET plasmas. In helium plasmas, ion cyclotron heating (ICRH) created fast α-particles, mimicking their populations in future burning plasmas. The recent successful Trace Tritium campaign provided important new data on fuel transport. Current enhancements on JET include a new ITER-like ELM-resilient high power ICRH antenna (7 MW) and over twenty new diagnostics that will further extend the JET scientific capabilities and push the facility even closer to the ITER parameters.A special mention is given to the involvement of the fusion experts from Association EURATOM-IPP.CR, who have been actively participating in the collective use of JET facility for more than three years. 相似文献
10.
J. Petrů 《Zeitschrift für Physik B Condensed Matter》1993,91(3):351-356
TheN-fold degenerate Anderson single impurity model in the infiniteU limit is treated by means of the irreducible Green functions method. In this approach a derivation of an exact Dyson equation and an exact self-energy operator is possible. The necessity of introducing auxiliary fields, such as slave-bosons is avoided. 相似文献