全文获取类型
收费全文 | 2643篇 |
免费 | 203篇 |
国内免费 | 175篇 |
专业分类
化学 | 1820篇 |
晶体学 | 136篇 |
力学 | 98篇 |
综合类 | 17篇 |
数学 | 203篇 |
物理学 | 747篇 |
出版年
2023年 | 19篇 |
2022年 | 47篇 |
2021年 | 57篇 |
2020年 | 55篇 |
2019年 | 59篇 |
2018年 | 47篇 |
2017年 | 79篇 |
2016年 | 101篇 |
2015年 | 65篇 |
2014年 | 96篇 |
2013年 | 233篇 |
2012年 | 151篇 |
2011年 | 185篇 |
2010年 | 138篇 |
2009年 | 117篇 |
2008年 | 174篇 |
2007年 | 138篇 |
2006年 | 153篇 |
2005年 | 143篇 |
2004年 | 89篇 |
2003年 | 71篇 |
2002年 | 70篇 |
2001年 | 44篇 |
2000年 | 48篇 |
1999年 | 36篇 |
1998年 | 18篇 |
1997年 | 21篇 |
1996年 | 30篇 |
1995年 | 26篇 |
1994年 | 28篇 |
1993年 | 26篇 |
1992年 | 26篇 |
1991年 | 26篇 |
1990年 | 15篇 |
1989年 | 18篇 |
1988年 | 20篇 |
1987年 | 23篇 |
1986年 | 25篇 |
1985年 | 17篇 |
1984年 | 32篇 |
1983年 | 23篇 |
1982年 | 26篇 |
1981年 | 27篇 |
1980年 | 20篇 |
1979年 | 23篇 |
1978年 | 17篇 |
1977年 | 12篇 |
1976年 | 14篇 |
1975年 | 17篇 |
1973年 | 16篇 |
排序方式: 共有3021条查询结果,搜索用时 62 毫秒
1.
Synthesis,spectral investigation and development of tetrahedral copper(II) complexes as artificial metallonucleases and antimalarial agents 下载免费PDF全文
Seven new copper(II) complexes of type [Cu(A)(L)]?H2O (A = sparfloxacin, ciprofloxacin, levofloxacin, gatifloxacin, pefloxacin, ofloxacin, norfloxacin; L = 5‐[(3‐chlorophenyl)diazenyl]‐4‐hydroxy‐1,3‐thiazole‐2(3H)‐thione) were synthesized and characterized using elemental and thermogravimetric analyses, and electronic, electron paramagnetic resonance (EPR), Fourier transform infrared and liquid chromatography–mass spectroscopies. Tetrahedral geometry around copper is assigned in all complexes using EPR and electronic spectral analyses. All complexes were investigated for their interaction with herring sperm DNA utilizing absorption titration (Kb = 1.27–3.13 × 105 M?1) and hydrodynamic volume measurement studies. The studies suggest the classical intercalative mode of DNA binding. The cleavage reaction on pUC19 DNA was monitored by agarose gel electrophoresis. The results indicate that the Cu(II) complexes can more effectively promote the cleavage of plasmid DNA. The superoxide dismutase mimic activity of the complexes was evaluated by nitroblue tetrazolium assay, and the complexes catalysed the dismutation of superoxide at pH = 7.8 with IC50 values in the range 0.597–0.900 μM. The complexes were screened for their in vitro antibacterial activity against five pathogenic bacteria. All the complexes are good cytotoxic agents and show LC50 values ranging from 5.559 to 11.912 µg ml?1. All newly synthesized Cu(II) complexes were also evaluated for their in vitro antimalarial activity against Plasmodium falciparum strain (IC50 = 0.62–2.0 µg ml?1). Copyright © 2015 John Wiley & Sons, Ltd. 相似文献
2.
Jigneshkumar P. Patel Zou Guo Xiang Shaw Ling Hsu Andrew B. Schoch Sena Ada Carleen Dean Matsumoto 《Journal of Polymer Science.Polymer Physics》2015,53(21):1519-1526
A uniform dispersion of reactants is necessary to achieve a complete reaction involving multicomponents. In this study, we have examined the role of plasticizer in the reaction of two seemingly unlikely reactants: a highly crystalline hexamethylenetetramine (HMTA) and a strongly hydrogen bonded phenol formaldehyde resin. By combining information from NMR, infrared spectroscopy and differential scanning calorimetry, we were able to determine the role of specific intermolecular interactions necessary for the plasticizer to dissolve the highly crystalline HMTA and to plasticize the phenol formaldehyde resin in this crosslinking reaction. The presence of the plasticizer increased the segmental mobility, disrupted the hydrogen bonded matrix, and freed the hydroxyl units, which further increased the solubility of the HMTA. Both the endothermic and exothermic transitions are accounted for in the calorimetric data obtained. For the first time, it is possible to obtain the effective molar ratio of each component needed to complete the crosslinking reaction efficiently. © 2015 Wiley Periodicals, Inc. J. Polym. Sci., Part B: Polym. Phys. 2015 , 53, 1519–1526 相似文献
3.
从推广的惠更斯-菲涅尔原理出发,推导出了部分相干电磁光束的偏振态在湍流介质中传输的表达式。并以电磁高斯-谢尔模型(EGSM)光束为例,研究了湍流对电磁高斯-谢尔模型光束偏振态的影响。研究结果表明,对于轴上点,湍流介质的折射率结构常数越大,偏振度趋于最大值的速度越快,达到的最大值越小;光斑越大,偏振度达到最大值的位置离光源越远,在光斑增大的过程中,偏振度所达到的极大值会先增大后减小,最后保持与光源相同的偏振度不变。对于轴外点,一个固定的z,光的偏振度随着离轴距离的增大而逐渐下降,并最终等于零。折射率结构常数越大,偏振度随离轴距离的增大而下降得越缓慢;光斑越大,偏振度随离轴距离的增大下降得越快。 相似文献
4.
Milan V. Patel Samir A. Patel Arabinda Ray Rajni M. Patel 《Journal of polymer science. Part A, Polymer chemistry》2004,42(20):5227-5234
Copolymers of monomers 2,4‐dichlorophenyl methacrylate (2,4‐DMA) and methyl methacrylate (MMA) were synthesized with different monomer feed ratios using toluene as a solvent and 2,2′‐azobisisobutyronitrile (AIBN) as an initiator at 70 °C. The copolymers were characterized by IR‐spectroscopy, and copolymer composition was determined with UV‐spectroscopy. The linearization method of Fineman–Ross was employed to obtain the monomer reactivity ratios. The molecular weights and polydispersity indexes were determined by gel permeation chromatography (GPC). Thermogravimetric analyses of polymers were carried out in nitrogen atmosphere. The homo‐ and copolymers were tested for their antimicrobial properties against selected microorganisms. © 2004 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 42: 5227–5234, 2004 相似文献
5.
以噻吩为单体,在等离子体环境中聚合成致密的有机膜。利用Rutherford背散射(RB2S)和质子弹性反冲(ERD)、傅里叶红外谱(FTIR)测定了膜的成分和结构;从近红外-可见-紫外光的反射和透射谱,运用传递矩阵方法研究了膜的光学性质;此外,还探讨了24keV的I+离子束的注入对等离子体噻吩聚合膜的掺杂效应。结果表明,注入层内电荷载流子的输运机理可用Mott的可变自由程跳跃(VRH)理论给以解释。
关键词: 相似文献
6.
Apurba Bhattacharya Nitin C. Patel Michael Peddicord Luca Parlanti John A. Grosso 《Tetrahedron letters》2006,47(30):5341-5343
An efficient, one-pot, phase transfer N-amination technology was developed. The protocol utilizes chloramine, an inexpensive and safe electrophilic aminating agent potentially viable for commercial manufacturing. 相似文献
7.
The selection of the branching variable can greatly affect the speed of the branch and bound solution of a mixed-integer or
integer linear program. Traditional approaches to branching variable selection rely on estimating the effect of the candidate
variables on the objective function. We present a new approach that relies on estimating the impact of the candidate variables
on the active constraints in the current LP relaxation. We apply this method to the problem of finding the first feasible
solution as quickly as possible. Empirical experiments demonstrate a significant improvement compared to a state-of-the art
commercial MIP solver. 相似文献
8.
G.Biju Kumar Hetal.V Patel Amrish C Shah Markus Trenkle Christine J Cardin 《Tetrahedron: Asymmetry》1996,7(12):3391-3396
N-Arylsulfonamides of (R)- and (S)-2-amino-1-butanol, on condensation with aromatic aldehydes produced diastereomerically pure 2-aryl-3-arenesulfonyl 4-ethyl-1,3-oxazolidines. The absolute configurations of one enantiomeric pair have been determined from two fully refined X-ray structures, supplemented by nmr data. 相似文献
9.
用光学多通道分析仪系统作高分辨光谱测量的技术 总被引:1,自引:0,他引:1
通常的光多通道分析仪(OMA)存在着同时谱宽与分辨率的矛盾.本文所述方法,在不减小谱宽的前提下,可将该分析仪光谱分辨率提高1~2量级,使之可适用于高分辨率谱研究. 相似文献
10.
Apurba Bhattacharya Nitin C. Patel Ritesh Tichkule Jiejun Wu 《Tetrahedron letters》2006,47(4):565-567
A simple, surfactant-mediated, one-pot, solvent-free dealkylative cleavage of aryl ethers and esters followed by subsequent optional trans-alkylation under essentially neutral conditions has been developed. 相似文献