多点侧面泵浦双包层光纤激光器的对称夹层结构

 利用基于亚波长衍射光栅理论的介质-金属-介质的对称夹层结构,对掺杂的双包层光纤进行多点泵浦，根据严格的电磁场衍射理论和光栅方程，分析了多点泵浦时，这种耦合结构的泵浦光泄露的问题，证明了多点泵浦时泵浦光的泄露率仅为15.52%，而对信号光则不存在泄露。这种对称夹层结构可以用于多个大功率激光二极管阵列的多点侧面泵浦双包层掺杂光纤中，以制作各种大功率(数kW级)稀土光纤激光器，其最大耦合效率可以达到80%以上。     

Temperature and magnetic field responsive hyaluronic acid particles with tunable physical and chemical properties

We report the preparation and characterization of thiolated-temperature-responsive hyaluronic acid-cysteamine-N-isopropyl acrylamide (HA-CYs-NIPAm) particles and thiolated-magnetic-responsive hyaluronic acid (HA-Fe-CYs) particles. Linear hyaluronic acid (HA) crosslinked with divinyl sulfone as HA particles was prepared using a water-in-oil micro emulsion system which were then oxidized HA-O with NaIO₄ to develop aldehyde groups on the particle surface_. HA-O hydrogel particles were then reacted with cysteamine (CYs) which interacted with aldehydes on the HA surface to form HA particles with cysteamine (HA-CYs) functionality on the surface. HA-CYs particles were further exposed to radical polymerization with NIPAm to obtain temperature responsive HA-CYs-NIPAm hydrogel particles. To acquire magnetic field responsive HA composites, magnetic iron particles were included in HA to form HA-Fe during HA particle preparation. HA-Fe hydrogel particles were also chemically modified. The prepared HA-CYs-NIPAm demonstrated temperature dependent size variations and phase transition temperature. HA-CYs-NIPAm and HA-Fe-CYs particles can be used as drug delivery vehicles. Sulfamethoxazole (SMZ), an antibacterial drug, was used as a model drug for temperature-induced release studies from these particles.     

A fuzzy stochastic model for telecommunications bandwidth brokers under probabilistic QoS measures

In this paper, we model and solve profit maximization problem of a telecommunications Bandwidth Broker (BB) under uncertain market and network infrastructure conditions. The BB may lease network capacity from a set of Backbone Providers (BPs) or from other BBs in order to gain profit by leasing already purchased capacity to end-users. BB’s problem becomes harder to deal with when bandwidth requests of end-users, profit and cost margins are not known in advance. The novelty of the proposed work is the development of a mechanism via combining fuzzy and stochastic programming methodologies for solving complex BP selection and bandwidth demand allocation problem in communication networks, based on the fact that information needed for making these decisions is not available prior to leasing capacity. In addition, suggested model aims to maximize BB’s decision maker’s satisfaction ratio rather than just profit. As a solution strategy, the resulting fuzzy stochastic programming model is transformed into deterministic crisp equivalent form and then solved to optimality. Finally, the numerical experiments show that on the average, proposed approach provides 14.30% more profit and 69.50% more satisfaction ratio compared to deterministic approaches in which randomness and vagueness in the market and infrastructure are ignored.     

GC-MS测定仲丁醇、富马酸二甲酯、咪唑和芝麻酚

建立了气相色谱串联质谱（GC-MS）准确、快速测定香精香料中仲丁醇、富马酸二甲酯、咪唑和芝麻酚的分析方法.样品经甲醇超声提取15min后,通过Agilent DB-WAX（0.25mm×30m×0.25μm）色谱柱分离,质谱进行定性,外标法对于4种目标物质进行定量分析.实验结果表明,在0.5-20mg/L的范围内,4种物质具有较好的线性,各待测物质的线性相关系数均大于0.9990,检出限为0.02-0.12mg/L,在1,5mg/L和10mg/L 3个加标水平条件下,4种禁限用物质的平均回收率为88.0％-113.1％,相对标准偏差为0.32％-6.53％.该方法前处理简单,灵敏度高,线性相关性好,重复性佳,可以满足香精香料中4种物质的同时检测.     

低温大试样热胀系数测试

本介绍了用熔融石英引伸法测量硬质材料热胀系数的简便装置,并给出了试样在液氦温区到室温的测量结果,数据的一致性以及与已有献数据比较取得了不错的结果．     

3-[二(羧甲基)氨甲基]-1, 2-二羟基蒽醌与蛋白质作用的研究

在pH4.1的缓冲溶液中,研究3-[二(羧甲基)氨甲基]-1,2-二羟基蒽醌(AFB)与牛血清蛋白(BSA)结合反应,相互生成的紫色的配合物。采用UV光谱法,测得此配合物的最大吸收峰值为510nm,与试剂本身相比较红移90nm。表观摩尔吸光系数ε=1.2474×10^4mol^-^1.cm^-^1.L,最大结合数n=7,表观结合常数K~c=3.85×10^6。研究发现,AFB与BSA之间主要是以分子之间的静电引力结合,认为该反应符合Scatchard模型。离子强度对结合反应有显著的影响。     

Evaluation of carbonic anhydrase and paraoxonase inhibition activities and molecular docking studies of highly water-soluble sulfonated phthalocyanines

The investigation of carbonic anhydrase and paraoxonase enzyme inhibition properties of water-soluble zinc and gallium phthalocyanine complexes ( 1 and 2 ) are reported for the first time. The binding of p-sulfonylphenoxy moieties to the phthalocyanine structure favors excellent solubilities in water, as well as providing an inhibition effect on carbonic anhydrase (CA) I and II isoenzymes and paraoxonase (PON1) enzyme. According to biological activity results, both complexes inhibited hCA I, hCA II, and PON1. Whereas 1 and 2 showed moderate hCA I and hCA II (off-target cytosolic isoforms) inhibitory activity (Ki values of 26.09 µM and 43.11 µM for hCA I and 30.95 µM and 33.19 µM for hCA II, respectively), they exhibited strong PON1 (associated with high-density lipoprotein [HDL]) inhibitory activity (Ki values of 0.37 µM and 0.27 µM, respectively). The inhibition kinetics were analyzed by Lineweaver–Burk double reciprocal plots. It revealed that 1 and 2 were noncompetitive inhibitors against PON1, hCA I, and hCA II. These complexes can be more advantageous than other synthetic CA and PON inhibitors due to their water solubility. Docking studies were carried out to examine the interactions between hCA I, hCA II, and PON1 inhibitors and metal complexes at a molecular level and to predict binding energies.     

中国声学学会2017年全国声学学术会议在哈尔滨召开

中国声学学会2017年全国声学学术会议在哈尔滨召开     

功率MOS器件单粒子栅穿效应的等效电路模拟方法

根据电路模拟软件ＰＳＰＩＣＥ内建元器件模型,建立了功率ＭＯＳ器件单粒子栅穿效应的等效电路模型和模型参数提取方法,对ＶＤＭＯＳ器件的单粒子栅穿效应机理进行了电路模拟和分析,模型结果与文献中的实验数据相符合,表明所建立的等效电路模拟方法是可靠的。     

Germatrane及其衍生物的合成新方法

本文报道了一种合成Germatrane及类似物Germatrantrione配合物的新方法. 有机锗倍半硫化物与三乙醇胺反应得Germatrane; 与氨三乙酸反应得Germatrantrione. 本文利用此法合成4个Germatrane类化合物(1), 5个Germatrantrione.DMF配合物(2), 2个Germatrantrione.DMSO配合物(3). 所有化合物经元素分析, IR, ^1H NMR, MS和差热-热失重分析 证实了它们的组成和结构.