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1.
Fernando Bento Cunha Karina Torres Pomini Ana Maria de Guzzi Plepis Virgínia da Conceio Amaro Martins Eduardo Gomes Machado Renato de Moraes Marcelo de Azevedo e Souza Munhoz Michela Vanessa Ribeiro Machado Marco Antonio Hungaro Duarte Murilo Priori Alcalde Daniela Vieira Buchaim Rogrio Leone Buchaim Victor Augusto Ramos Fernandes Eliana de Souza Bastos Mazuqueli Pereira Andr Antonio Pelegrine Marcelo Rodrigues da Cunha 《Molecules (Basel, Switzerland)》2021,26(6)
Autologous bone grafts, used mainly in extensive bone loss, are considered the gold standard treatment in regenerative medicine, but still have limitations mainly in relation to the amount of bone available, donor area, morbidity and creation of additional surgical area. This fact encourages tissue engineering in relation to the need to develop new biomaterials, from sources other than the individual himself. Therefore, the present study aimed to investigate the effects of an elastin and collagen matrix on the bone repair process in critical size defects in rat calvaria. The animals (Wistar rats, n = 30) were submitted to a surgical procedure to create the bone defect and were divided into three groups: Control Group (CG, n = 10), defects filled with blood clot; E24/37 Group (E24/37, n = 10), defects filled with bovine elastin matrix hydrolyzed for 24 h at 37 °C and C24/25 Group (C24/25, n = 10), defects filled with porcine collagen matrix hydrolyzed for 24 h at 25 °C. Macroscopic and radiographic analyses demonstrated the absence of inflammatory signs and infection. Microtomographical 2D and 3D images showed centripetal bone growth and restricted margins of the bone defect. Histologically, the images confirmed the pattern of bone deposition at the margins of the remaining bone and without complete closure by bone tissue. In the morphometric analysis, the groups E24/37 and C24/25 (13.68 ± 1.44; 53.20 ± 4.47, respectively) showed statistically significant differences in relation to the CG (5.86 ± 2.87). It was concluded that the matrices used as scaffolds are biocompatible and increase the formation of new bone in a critical size defect, with greater formation in the polymer derived from the intestinal serous layer of porcine origin (C24/25). 相似文献
2.
We analyze the dynamics of an AdS5 braneworld with matter fields when gravity is allowed to deviate from the Einstein form on the brane. We consider exact five-dimensional warped solutions which are associated with conformal bulk fields of weight –4 and describe on the brane the following three dynamics: those of inhomogeneous dust, of generalized dark radiation, and of homogeneous polytropic dark energy. We show that, with modified gravity on the brane, the existence of such dynamical geometries requires the presence of non-conformal matter fields confined to the brane. 相似文献
3.
In this paper, space adaptivity is introduced to control the error in the numerical solution of hyperbolic systems of conservation laws. The reference numerical scheme is a new version of the discontinuous Galerkin method, which uses an implicit diffusive term in the direction of the streamlines, for stability purposes. The decision whether to refine or to unrefine the grid in a certain location is taken according to the magnitude of wavelet coefficients, which are indicators of local smoothness of the numerical solution. Numerical solutions of the nonlinear Euler equations illustrate the efficiency of the method. 相似文献
4.
The construction of non-Abelian affine Toda models is discussed in terms of its underlying Lie algebraic structure. It is shown that a subclass of such non-conformal two-dimensional integrable models naturally leads to the construction of a pair of actions, which share the same spectra and are related by canonical transformations. 相似文献
5.
Minimal, rigid foliations by curves on ℂℙ
n 总被引:1,自引:0,他引:1
We prove the existence of minimal and rigid singular holomorphic foliations by curves on the projective space ℂℙ
n
for every dimension n≥2 and every degree d≥2. Precisely, we construct a foliation ℱ which is induced by a homogeneous vector field of degree d, has a finite singular set and all the regular leaves are dense in the whole of ℂℙ
n
. Moreover, ℱ satisfies many additional properties expected from chaotic dynamics and is rigid in the following sense: if
ℱ is conjugate to another holomorphic foliation by a homeomorphism sufficiently close to the identity, then these foliations
are also conjugate by a projective transformation. Finally, all these properties are persistent for small perturbations of
ℱ.?This is done by considering pseudo-groups generated on the unit ball 𝔹
n
⊆ℂ
n
by small perturbations of elements in Diff(ℂ
n
,0). Under open conditions on the generators, we prove the existence of many pseudo-flows in their closure (for the C
0-topology) acting transitively on the ball. Dynamical features as minimality, ergodicity, positive entropy and rigidity may
easily be derived from this approach. Finally, some of these pseudo-groups are realized in the transverse dynamics of polynomial
vector fields in ℂℙ
n
.
Received March 7, 2002 / final version received November 26, 2002?Published online February 7, 2003
Most of this work has been carried out during a visit of the first author to IMPA/RJ and a visit of the second author to the
University of Lille 1. We would like to thank these institutes for hospitality and express our gratitude to CNPq-Brazil and
CNRS-France for the financial support which made these visits possible. We are also indebted to Paulo Sad, Marcel Nicolau
and the referee whose comments helped us to improve on the preliminary version. Finally, the second author has partially conducted
this research for the Clay Mathematics Institute. 相似文献
6.
7.
8.
P.R.S. Gomes I. Padron E. Crema O.A. Capurro J.O. Fernández Niello G.V. Marti A. Arazi M. Trotta J. Lubian M.E. Ortega A.J. Pacheco M.D. Rodríguez J.E. Testoni R.M. Anjos L.C. Chamon M. Dasgupta D.J. Hinde K. Hagino 《Physics letters. [Part B]》2006
Complete and incomplete fusion cross sections for the 9Be + 144Sm reaction have been measured at near-barrier energies, using the delayed X-ray detection technique. At above-barrier energies these show a suppression of complete fusion for this weakly bound projectile on an intermediate mass target. The suppression factor, attributed to 9Be break-up, was deduced from a comparison of complete fusion yields with coupled-channels calculations, and appears consistent with measured incomplete fusion product yields. At ∼10%, it is considerably smaller than the value of ∼30% previously found for a 208Pb target. Simultaneous measurements of elastic and inelastic scattering permit a clearer picture of the reaction mechanisms. 相似文献
9.
Alternatives based on polynomial expansions of gaussian basis set exponents are introduced and evaluated. The formulas presented here outperform methods based upon the even-tempered formula or combinations of it. They closely match the performance of other methods based upon larger polynomial expansions of the logarithm of the exponents using the same or one less parameter per orbital angular symmetry. 相似文献
10.
Ligia E. Zamora G. A. Perez Alcazar J. M. Greneche S. Suriñach 《Hyperfine Interactions》2006,168(1-3):1057-1063
Fe60Mn10Al20Nb10, (Fe60Mn10Al30)95Nb5 and (Fe60Mn10Al30)90Nb10 ball milled powdered alloys were investigated using X-ray diffraction, Mössbauer spectrometry, thermomagnetic (TGM) and magnetization measurements. We studied the influence of Nb content and of different milling times on the structural and magnetic properties. Two main features can be concluded: (1) the FeAlMn induces a BCC phase whatever the Nb content is, and (2) as both increasing Nb content and milling time give rise to an highly disordered state in conjunction with a decrease of the ferromagnetic behavior. 相似文献