丙环唑配合物的合成、缓释性能及生物活性研究

Five propiconazole(L) complexes (ML₂Cl₂, M=Zn(Ⅱ), Cu(Ⅱ), Co(Ⅱ); ML₄Cl₂, M=Ni(Ⅱ), Mn(Ⅱ)) were prepared and characterized by elemental analysis and IR. These complexes exhibited favorable controlled release property, it took 40 to 120 hours to release 85% amount of ligand in the water. The toxicity determination to Botrytis cinera, Rhizoctonia cerealis, Gibberella zeae, Fussrium moniliforme and Colletotrichum orbiculare indicated that the fungicidal activities of the complexes were better than that of the ligand except Mn-complex to Rhizoctonia cereali. The EC50 of Zn-propiconazole were 0.045 2～0.144 1 μg·mL^-1, Co- and Ni-propiconazole were 0.066 3～0.210 4 μg·mL^-1 and 0.183 9～0.340 7 μg·mL^-1, respectively, and Mn-propiconazole were only 0.353 6～0.538 0 μg·mL^-1. The growth regulation experiment to wheat seeding by dressing treating indicated that inhibiting activities of the complexes to root length and stem height were weaker than that of the ligand.     

丙环唑-铜(Ⅰ)配合物的极谱法研究

在pH=8.00的0.4 mol/L NH3-NH4Cl缓冲溶液中,丙环唑与铜(Ⅰ)配位并在-0.88 V(vs.SCE)处产生新的还原峰,用线性扫描循环法测定此峰为不可逆,其峰电流与丙环唑浓度在6.00×10-6~8.00×10-5mol/L范围内呈现良好的线性关系,相关系数r=0.9989;检出限为4.00×10-6mol/L;测得电活性配合物丙环唑-铜(Ⅰ)中丙环唑与铜(Ⅰ)之比为2∶1,稳定常数为5.81×1012。