排序方式: 共有4条查询结果,搜索用时 93 毫秒
1
1.
Using both mixed lymphocyte reaction (MLR) and graft-versus-host reaction (GVHR) assays, investigations have been made on 60 multiparous mice of late pregnancy, derived from C57BL mating with SWI as well as C57BL mating with BGI. The results demonatrate the presence of suppressor cells both in uterus-draining-lymphnodes (DLN) and in spleen of allogeneie pregnant mice. The suppressive immune regulatory activity mediated by these cells might play an important role in the successful maintenance of fetus allograft. The possible mechanisms about the inducing of the changes in lymphocyte subpopulation are also studied in this paper. 相似文献
2.
3.
4.
Using a method from Billingham, an animal model of the neonatal allotransplantation tolerance of SWI to C57BL inbred mice was established and the mechanism of neonatal tolerance established by us was preliminarily studied.Our experiment indicates that the clonal deletion theory is not the unique explanation for the neonatal tolerance and a peripheral active inhibitory mechanism including suppressor cells may participate in meditating and maintaining the neonatal tolerance.The suppressor cells in the neonatal tolerance are radioresistant, but rather sensitive to mitomyein C treatment. These results suggest that suppressor cell population may be nonhomogenous. Further studies about this problem are needed. 相似文献
1