Gauge fields, geometric phases, and quantum adiabatic pumps

Quantum adiabatic pumping of charge and spin between two reservoirs (leads) has recently been demonstrated in nanoscale electronic devices. Pumping occurs when system parameters are varied in a cyclic manner and sufficiently slowly that the quantum system always remains in its ground state. We show that quantum pumping has a natural geometric representation in terms of gauge fields (both Abelian and non-Abelian) defined on the space of system parameters. Tunneling from a scanning tunneling microscope tip through a magnetic atom could be used to demonstrate the non-Abelian character of the gauge field.     

Consideration of molecular weight during compound selection in virtual target-based database screening

Virtual database screening allows for millions of chemical compounds to be computationally selected based on structural complimentary to known inhibitors or to a target binding site on a biological macromolecule. Compound selection in virtual database screening when targeting a biological macromolecule is typically based on the interaction energy between the chemical compound and the target macromolecule. In the present study it is shown that this approach is biased toward the selection of high molecular weight compounds due to the contribution of the compound size to the energy score. To account for molecular weight during energy based screening, we propose normalization strategies based on the total number of heavy atoms in the chemical compounds being screened. This approach is computationally efficient and produces molecular weight distributions of selected compounds that can be selected to be (1) lower than that of the original database used in the virtual screening, which may be desirable for selection of leadlike compounds or (2) similar to that of the original database, which may be desirable for the selection of drug-like compounds. By eliminating the bias in target-based database screening toward higher molecular weight compounds it is anticipated that the proposed procedure will enhance the success rate of computer-aided drug design.     

A new model of crystal packing

A new, conceptually simple model of crystal packing is proposed which uses "packing patterns" to describe unit cells in terms of molecular building blocks.     

A result about a selection problem of Michael

It is shown that a continuum that is an space in the sense of Michael must be hereditarily decomposable. This improves known results, thereby providing more evidence that such continua must be dendrites.

     

The identification of tyre induced vehicle interior noise

Sound transmission into a vehicle is classified as either airborne or structure borne sound. From the point view of noise control, the reduction of noise transferred by different paths requires different solutions. Coherence function analysis is often used to identify transmission paths. However it can be difficult to separate the airborne from structure borne components. The principle of acoustic reciprocity offers a convenient method for overcoming this difficulty. The principal states that the transfer function between an acoustic volume velocity source and an acoustic receiver is independent of a reversal of the position of source and receiver. The work done on this study involves exciting a stationary tyre and measuring the surface velocity of the tyre at a number of discrete points. The acoustic transfer functions between each point on the tyre and a receiver point are measured reciprocally. Two sets of measurements are then combined to yield a measure of the sound pressure due to a point force on the tyre via the acoustic transmission path only. This technique also provides information on the relative contributions of various regions of the tyre wall to the resultant noise. Also the sound radiation characteristics, the horn effect, and resonance at the wheel housing are identified through the reciprocal measurement.     

A study on radial directional natural frequency and damping ratio in a vehicle tire

The measurement of radial directional natural frequency and damping ratio in a vehicle tire has been studied. Natural frequencies and damping ratios in the radial direction of various tires, from passenger car tires to truck bus tires, are reported. The radial direction modal parameters of tires subjected to different levels of inflation pressure, have been determined by using a frequency response function method. To obtain the theoretical natural frequency and mode shape, the plane vibration of a tire has been modeled as though it were that of a circular beam. By using the Tielking method that is based on Hamilton’s principle, theoretical results have been determined by considering the rotational velocity, tangential and radial stiffness, radial directional velocity and tension force which is due to tire inflation pressure. The results show that experimental conditions can be considered as the parameters that shift the natural frequency and damping ratio.     

Measurement of multiperiod aggregative efficiency

This article proposes a new method for measuring an aggregative efficiency of multiple period production systems. Every organization or firm generates a time series of data that represent its performances in the resource utilization and output production over multiple periods, and often desires an aggregated measure of efficiency for several periods of interest. Data envelopment analysis (DEA) has become an accepted and well-known approach to evaluating efficiency performance in a wide range of cases. However, most of the DEA studies have dealt primarily with ways to gauge the efficiency of production in only a single period so this efficiency reflects the insufficient or partial performance of multiple period productions. The new method is developed through extensions of the concept of Debreu–Farrell technical efficiency and is applied to evaluating the efficiency of cable TV service units with 3-year data.