太阳能帆板平面度测量系统中光斑图像处理方法研究

太阳能帆板的平面度测量是卫星生产制造过程中的一个关键技术，现有的测量方法存在着精度差，效率低的问题。该文在基于实际工程课题的太阳能帆板平面度测量系统基础上，针对测量系统中光斑图像处理这一关键技术进行了详细的研究。对现有测量方法进行了比较与分析，介绍了测量系统的基本原理、图像采集系统设计过程中采取的主要措施、图像处理的具体方法与步骤和测量系统的基本组成。提出了一种新的快速滤波算法和光斑图像能量中心求取算法，大大提高了光斑图像能量中心的求取精度和实时性，提高了太阳能帆板平面度的测量精度。给出了光斑图像处理结果、静态测量重复性误差以及实际帆板的测量结果与分析，实验结果证明所采用的光斑图像处理方法可以满足对实际帆板测量精度的要求。     

Simultaneous determination of ten flavonoids of crude and wine‐processed Radix Scutellariae aqueous extracts in rat plasma by UPLC‐ESI‐MS/MS and its application to a comparative pharmacokinetic study

Radix Scutellariae (RS) is a herbal medicine with various pharmacological activities to treat inflammation, respiratory and gastrointestinal infections, etc. In this study, a rapid, sensitive and selective UPLC‐ESI‐MS/MS method was developed for simultaneous determination of 10 flavonoids – scutellarin, scutellarein, chrysin, wogonin, baicalein, apigenin, wogonoside, oroxylin A‐7‐O‐glucuronide, oroxylin A and baicalin – from RS aqueous extracts in rat plasma with propyl paraben as internal standard (IS). Chromatographic separation was achieved on a C₁₈ column using gradient elution with the mobile phase consisting of methanol and water (containing 0.1% formic acid) at a flow rate of 0.2 mL/min. The detection was performed in multiple reaction monitoring mode using electrospray ionization in negative mode. The validated method showed good linearity over a wide concentration range (r >0.9935). The intra‐ and interday assay variabilities were <9.5% and <12.4% for all analytes, respectively. The extraction recovery ranged from 71.2 to 89.7% for each analyte and IS. This method was successfully applied to pharmacokinetic comparision after oral administration of crude and wine‐processed RS aqueous extracts. There were significant differences in some pharmacokinetic parameters of most analytes between crude and wine‐processed RS. This suggested that wine‐processing exerted effects absorption of most flavonoids. Copyright © 2014 John Wiley & Sons, Ltd.     

食品接触材料中化合物的非靶向筛查技术研究进展

近年来,食品接触材料中的化合物迁移作为食品安全风险的重要来源受到越来越多的关注,推动了分析技术的快速发展。传统的靶向筛查技术只关注部分有意添加物或少量非有意添加物,无法对可能存在的其他大量物质进行扫描和具体分析。而非靶向筛查技术则可以覆盖所有能检出的成分,能提供尽可能全面的迁移物信息和数据,从而为针对食品接触材料的风险评估、立法和风险管理工作提供科学支撑。但现今针对食品接触材料的非靶向筛查分析技术仍存在不少挑战。该文集中对食品接触材料中化合物的非靶向筛查技术进行综述,全面梳理和介绍了食品接触材料中化合物提取和定性分析技术的进展;重点讨论了在质谱分析中,质谱库特别是开放质谱库、高分辨率质谱、开源工具、与食品接触材料相关的化学结构数据库、保留时间指数和碰撞截面积预测模型等在食品接触材料组分鉴定中的潜在作用,以期为行业利用这些资源和工具开展食品接触材料组分的非靶向筛查工作提供参考。     

Effects of digital processing on repeatability assessment of a multiple reaction monitoring liquid chromatography–tandem mass spectrometry system by ISO 11843-7

ISO 11843 part 7 (ISO 11843-7) can provide a standard deviation (SD) of area measurements of a target peak through the stochastic behaviors of instrumental noises. The purpose of this study is to demonstrate that ISO 11843-7 can be applied to assess repeatability in an isocratic liquid chromatography–tandem mass spectrometry (LC–MS/MS) system without repetitive measurements. The relative standard deviation (RSD) of the peak area of ergosterol picolinyl ester, which was used as an example, on a multiple reaction monitoring (MRM) chromatogram was determined by ISO 11843-7. The RSD by ISO 11843-7 (N = 1) was within a 95% confidence band of the RSD by repetitive measurements (N = 6). Moreover, the effects of digital smoothing, such as moving average, were also examined on the repeatability assessment in LC–MS/MS by ISO 11843-7. From the results of the comparisons of the RSDs obtained by ISO 11843-7 and the repetitive measurements, it was shown that suitable RSDs of the peak area were obtained from the smoothed MRM chromatograms by the moving average for narrow data point windows (e.g., one-sixth of the peak width). In conclusion, the utility of repeatability assessment based on ISO 11843-7 has been expanded for the validation of an LC–MS/MS system.     

Process-Structure-Formulation Interactions for Enhanced Sodium Ion Battery Development: A Review

Before the viability of a cell formulation can be assessed for implementation in commercial sodium ion batteries, processes applied in cell production should be validated and optimized. This review summarizes the steps performed in constructing sodium ion (Na-ion) cells at research scale, highlighting parameters and techniques that are likely to impact measured cycling performance. Consistent process-structure-performance links have been established for typical lithium-ion (Li-ion) cells, which can guide hypotheses to test in Na-ion cells. Liquid electrolyte viscosity, sequence of mixing electrode slurries, rate of drying electrodes and cycling characteristics of formation were found critical to the reported capacity of laboratory cells. Based on the observed importance of processing to battery performance outcomes, the current focus on novel materials in Na-ion research should be balanced with deeper investigation into mechanistic changes of cell components during and after production, to better inform future designs of these promising batteries.     

Laser-induced forward-transfer with light possessing orbital angular momentum

Helical light fields may carry both orbital angular and spin angular momentum which is respectively associated with their helical wavefronts (optical vortices) and rotating transverse electric fields. Interestingly, these helical light fields interact with materials and the orbital angular momentum of these fields can physically twist a range of materials, including metals, semiconductors, polymers, and liquids. With the aid of spin angular momentum, these fields can also form a range of helical structures. This light-matter interaction based on transfer of angular momentum has the potential to revolutionize industrial processes and enable technologies, such as advanced non-contact and nozzle-free printing. In this review paper, we focus on this printing technique, a process which we herein refer to as optical vortex laser induced forward transfer, and we show how it can be used for the production of next generation printed photonics/electronics/spintronics devices. Herein we review the interactions between the angular momentum of light and materials, and we discuss the ways in which optical vortices can be used to produce a variety of exotic structures. We also discuss the current state-of-the art of laser-induced forward-transfer technologies and detail some of the most novel devices, which have been fabricated using this optical vortex laser induced forward transfer, including hexagonal close-packed photonic-rings and plasmonic nanocores.     

Identification of Pipeline Inner Wall Geometry Based on the POD⁃RBF Method北大核心CSCD

Based on the proper orthogonal decomposition⁃radial basis function (POD⁃RBF), a geometric identification method for pipeline inner wall was proposed to solve the internal corrosion detection problem of natural gas and oil pipelines. In view of the static magnetic field, the simplified finite element model for the pipelines was established, and the variable⁃geometry sample library was constructed, to realize the response prediction of arbitrary geometry by the POD⁃RBF. The proposed method achieves reduced⁃order analysis and avoids repeated solution of the stiffness matrix due to the geometrical change during the identification process. Hence, it can significantly improve the computation efficiency. Finally, the grey wolf optimization (GWO) algorithm was used to optimize the objective function and avoid the calculation of the sensitivity in the process of geometry change. The numerical examples show that, the proposed method has high efficiency and accuracy in the geometric identification of the pipeline inner wall, with good stability even under introduced noises. © 2023 Editorial Office of Applied Mathematics and Mechanics. All rights reserved.     

一种简易医用硬性内窥镜相对百分畸变检测系统

医用硬性内窥镜作为诊治医疗器械,其畸变直接影响医生对手术位置判断的准确性,因此内窥镜相对百分畸变的测量是一个亟需解决的问题。设计了一种基于图像处理的相对百分畸变检测系统,通过CCD相机采集校准靶板图像,对内窥镜视轴和目标靶板的板面进行垂直校准后,更换畸变靶板采集图像,计算机将得到的图像进行滤波、感兴趣区域提取和尺寸统计,最终获得相对百分畸变。以30°腹腔内窥镜为测量模型,实验得到设计的校准系统在待测内窥镜全视场70%位置所测量的相对百分畸变值优于未垂直校准系统2.2%。结果表明,系统的检测结果一致性较高,且准确度高于未垂直校准系统。     

Influenza virus pathogenicity regulated by host cellular proteases,cytokines and metabolites,and its therapeutic options

Influenza A virus (IAV) causes significant morbidity and mortality. The knowledge gained within the last decade on the pandemic IAV(H1N1)2009 improved our understanding not only of the viral pathogenicity but also the host cellular factors involved in the pathogenicity of multiorgan failure (MOF), such as cellular trypsin-type hemagglutinin (HA₀) processing proteases for viral multiplication, cytokine storm, metabolic disorders and energy crisis. The HA processing proteases in the airway and organs for all IAV known to date have been identified. Recently, a new concept on the pathogenicity of MOF, the “influenza virus–cytokine–trypsin” cycle, has been proposed involving up-regulation of trypsin through pro-inflammatory cytokines, and potentiation of viral multiplication in various organs. Furthermore, the relationship between causative factors has been summarized as the “influenza virus–cytokine–trypsin” cycle interconnected with the “metabolic disorders–cytokine” cycle. These cycles provide new treatment concepts for ATP crisis and MOF. This review discusses IAV pathogenicity on cellular proteases, cytokines, metabolites and therapeutic options.     

基于二维细分技术的时栅信号处理系统设计

为了提高时栅位移传感器的动态性能及测量精度,提出了一种基于FPGA和二维细分技术的时栅位移传感器信号处理系统。利用二维细分技术对插补脉冲进行倍频处理,降低了对插补脉冲频率的要求,通过倍频后的高频脉冲插补时栅感应信号和参考信号之间的相位差完成了时栅角位移的测量,提高测量精度。该系统在FPGA内基于NiosII软核完成数据的采集和处理,简化了系统,并加入自定义指令提高了数据处理效率。实验表明,采用该系统后,时栅位移传感器在960MHz插补脉冲下测量误差峰峰值为±1.3″,实现了时栅的高精度角位移测量。