Enhancement of frequency modulation response time for polymer-dispersed liquid crystal

Through the ferroelectric nanoparticles of BaTiO₃ (BTO) doping, the response time for the frequency modulation of the polymer-dispersed liquid crystal (PDLC) was improved. The BTO-doped PDLC cells were prepared by polymerisation induced phase separation (PIPS) process using UV light. The capacitance of the PDLC composites was measured with an impedance analyzer in the frequency range of 100 Hz–1 MHz at 1 V. The dynamic signal for the response time of the PDLC devices was monitored through a digital oscilloscope. The electro-optical properties of the PDLC were found to strongly depend on the doped BTO concentration. The BTO doping caused a large increase in the capacitance. The dielectric constants were drastically decreased in the samples with rather low BTO doping ratio at a high frequency. No outstanding difference in the rising time of the LC was observed in the BTO-doped PDLC device, but the falling time was significantly decreased from 0.334 to 0.094 s. The present results imply that the nanoparticle-doping technology could improve the electro-optical performance of the PDLC requiring fast response and frequency modulation, such as optical modulators and PDLC-hybrid electroluminescence device for flexible electronic devices.     

Ultrafast shock compression of PDMS‐based polymers

The shock response of polymers is important for a number of commercial and defense‐related applications, but it is difficult to obtain empirical shock response data over the wide range of preparations and aging conditions typically found in such applications. Ultrafast compression is useful to characterize polymer shock response over a wide range of polymer initial conditions due to the high throughput of this method. To establish greater confidence in ultrafast compression experiments and to characterize the detailed shock response of several variations in a single base polymer, the results of sub‐nanosecond shock compression experiments in ∼5 μm thick layers of the polydimethylsiloxane (PDMS)‐based elastomeric rubbers Sylgard‐184, SE1700, and an unfilled, end‐linked model PDMS network are presented. The results of conventional ultrafast shock etalon measurements to time‐of‐flight measurements for similar thickness layers of irradiated and unirradiated SE1700 are compared. Good agreement between the shock response measured by these two ultrafast shock methods, as well as consistency between ultrafast data and long time scale gas gun data is found. From measurements across a variety of PDMS formulations, a statistically significant variation in the shock response with the quasistatic elastic modulus is presented. Published 2018.^† J. Polym. Sci., Part B: Polym. Phys. 2018 , 56, 827–832     

Effect of the polarisation direction and incident angle of a UV light on the electrooptical response of the polymer-stabilised vertically aligned in-plane switching liquid crystal

We investigated the effect of the polarisation direction and incident angle of a UV light on the electrooptical properties of the polymer-stabilised vertically aligned in-plane switching (PS-VAIPS) liquid crystal. The PS-VAIPS sample cured with a UV light whose polarisation was parallel to the projected direction of the in-plane electric field showed greater transmittance, faster rising time and slower falling time than the sample cured with a UV light with a perpendicular polarisation to the electric field. In addition, the PS-VAIPS sample showed slower rising time and faster falling time with increasing incident angle of the UV light.     

一种内压膨胀系统的动态响应分析

论文采用LS-DYNA非线性动力学有限元程序,对一种曲边柱壳-多体内压膨胀系统在均布内压作用下的动态膨胀过程进行了数值分析,获得了曲边柱壳动态响应规律.文中分析了各种因素对曲边柱壳的变形模式及其应力、应变变化规律的影响；模拟了曲边柱壳在内部压力和外围变形体共同作用下的耦合变形运动过程.模拟计算结果与试验现象基本一致.     

Evaluation of relative MS response factors of drug metabolites for semi‐quantitative assessment of chemical liabilities in drug discovery

Drug metabolism studies are performed in drug discovery to identify metabolic soft spots, detect potentially toxic or reactive metabolites and provide an early insight into potential species differences. The relative peak area approach is often used to semi‐quantitatively estimate the abundance of metabolites. Differences in the liquid chromatography‐mass spectrometry responses result in an underestimation or overestimation of the metabolite and misinterpretation of results. The relative MS response factors (RF) of 132 structurally diverse drug candidates and their 233 corresponding metabolites were evaluated using a capillary‐liquid chromatography/high‐resolution mass spectrometry system. All of the synthesized metabolites discussed here were previously identified as key biotransformation products in discovery investigations or predicted to be formed. The most commonly occurring biotransformation mechanisms such as oxygenation, dealkylation and amide cleavage are represented within this dataset. However, relatively few phase II metabolites were evaluated because of the limited availability of authentic standards. Approximately 85% of these metabolites had a relative RF in the range between 0.2 (fivefold under‐prediction) and 2.0 (twofold over‐prediction), and the median MS RF was 0.6. Exceptions to this included very small metabolites that were hardly detectable. Additional experiments performed to understand the impact of the MS platform, flow rate and concentration suggested that these parameters do not have a significant impact on the RF of the compounds tested. This indicates that the use of relative peak areas to semi‐quantitatively estimate the abundance of metabolites is justified in the drug discovery setting in order to guide medicinal chemistry efforts. Copyright © 2017 John Wiley & Sons, Ltd.     

金属蜂窝夹芯结构抗水下冲击性能

为揭示高强度水下爆炸冲击载荷作用下金属夹芯结构的抗冲击性能,在实验室开展小尺寸水下爆炸加载技术对金属蜂窝夹芯结构性能影响的实验研究。基于实验结果,开展了全尺寸数值模拟金属蜂窝夹芯结构在水下冲击载荷作用下的动态响应和抗冲击性能研究。结果表明,数值模拟、实验和理论模型计算的结果具有良好的一致性。由于蜂窝芯材相对密度对夹芯结构能量耗散方式和载荷传递机制的影响,结构动态响应、失效模式以及抗冲击性能随着冲击强度的变化表现出较为明显的不同。通过抗冲击参数分析,建立了反映金属蜂窝夹芯结构抗冲击性能的结构横向变形、固支反力、透射脉冲和塑性能耗随冲击强度和芯材相对密度变化的结构-载荷-性能量化关系。     

A model for torsion-stress effect on nonlinear magnetoimpedance in amorphous wires with negative magnetostriction

A model to describe the influence of torsional stress on nonlinear magnetoimpedance in amorphous wires with negative magnetostriction is proposed. The nonlinear voltage response is found in the framework of the low-frequency approximation taking into account the spatial distribution of the circular magnetic field and the magnetoelastic anisotropy induced by the torsional stress. It is demonstrated that the application of torsional stress results in an increase of the second harmonic amplitude in voltage due to a reinforcement of helical anisotropy in the wire. The second harmonic amplitude is analyzed as a function of external field, torsional stress and current amplitude. The ranges of torsional stress and current amplitude to achieve maximal field sensitivity of the second harmonic are found.     

顶爆和拱腰侧爆同时作用下锚固洞室的动态响应

基于相似模型试验,采用显式非线性动力分析程序LS-DYNA3D研究了地下锚固洞室在拱顶和拱腰侧两处集中装药爆源同时爆炸作用下应力波传播规律、裂纹形成机理以及洞壁围岩位移分布特征。通过对比分析顶爆试验和计算模型的压应力时程曲线,发现模拟与试验结果吻合,且符合应力波的传播规律,表明数值模拟结果可靠。爆源爆炸后,应力波以圆形向周围岩体传播,两应力波相遇处压应力强度明显大于周围岩体;当应力波传到自由面时,会反射形成拉伸波,在地表下方和洞室上方发生“层裂”现象,在拱顶和拱腰侧爆源中间沿洞室径向有裂纹延伸,由于拉伸波的叠加,在爆源下方出现“八”字形的锥形裂纹面。锚杆能够起到加固岩体的作用,锚固洞室比毛洞裂纹分布少,毛洞迎爆侧裂纹主要为横向裂纹,而锚固洞室则为径向劈裂和横向裂纹。两爆源中点洞室径向处的洞壁围岩位移峰值最大,极易产生破坏。     

Linear and Star-Shaped Extended Di- and Tristyrylbenzenes: Synthesis,Characterization and Optical Response to Acid and Metal Ions

Two linear 1,4-distyrylbenzenes and five star-shaped 1,3,5-tristyrylbenzene derivatives ( L_2a and L_2b , Y₀–Y₃ and Y_NBu ) were synthesized and spectroscopically characterized. The photophysical properties, optical response to acid and metal ions were investigated. Upon backbone extension of linear distyrylbenzenes or the introduction of dibutylanilines, the electronic spectra are redshifted. Incorporation of electron-deficient pyridyl units does not significantly affect the optical properties. Variation of the number of pyridine rings and substitution pattern tune the fluorescence response to acids and metal ions. The novel arenes discriminate Al³⁺, Mn²⁺, Fe³⁺, Fe²⁺, Cd²⁺, Ag⁺ and Hg²⁺.     

Surfaces Decorated with Polymeric Nanocompartments for pH Reporting

Here we present a novel active surface that demonstrates pH responsiveness and can be used as a platform for designing ‘smart labels’. To generate our active surfaces, we immobilized polymer nanocompartments onto glass surfaces using thiol–ene chemistry. Prior to surface attachment, a pH responsive model dye was encapsulated within nanocompartments at two different pH values. We confirmed the attachment and distribution of dye‐loaded polymersomes and established the pH responsiveness of the active surface construct. The strategy presented here was carefully chosen to obtain small sized functional surfaces from commercially available materials that can be easily integrated into intelligent packaging systems. The ability to miniaturize such smart labels, while still being able to detect their response to the environment, is a crucial step towards developing active surfaces suitable for food packaging applications.