润滑剂边界滑移及其对弹流润滑特性的影响

基于润滑剂在弹性流体动力润滑状态下表现出类似塑件固体的非牛顿特性，根据塑性屈服和流体动力润滑理论，建立了考虑润滑剂在固液界面滑移的线接触弹流润滑失效预测模型。计算结果显示：载荷和滑滚比对润滑油膜厚度影响显著；在一定载荷和滑滚比下，润滑油膜将丧失承载能力而破裂。与现有理论及实验数据对比，线接触弹流润滑失效预测模型的计算结果与实验结果具有较好的一致性。     

惯导系统故障诊断技术的特点

对惯导系统故障诊断技术的特点作了简要而全面的论述。论述的内容包括基本功能、故障分类、故障现象及原因，指出各类故障诊断方法的问题，并提出了智能故障诊断构思。     

大型相关失效工程网络系统可靠度的近似算法

为避开失效模式(或系统可靠路径)的NP难题(non—polynomial increase hard problem)，提出递推分解算法，降低大型工程网络系统可靠度分析中的计算复杂性，同时，将改进的多维正态变量积分公式，引入递推分解算法之中，计算多失效模式(或系统可靠路径)的联合概率，并最终计算工程网络系统的失效概率和可靠度，对于特别复杂的工程网络系统，采用上下界的方法，给出具有很高精度的可靠度近似值。实例分析表明，本文提出的方法，具有较高的精度和计算效率。     

疲劳损伤临界值分析

通过对疲劳过程和疲劳失效的临界状态的分析，提出疲劳失效判据应与损伤程度和应力水平两个因素有关，并在试验的基础上建立了一个剩余强度退化的对数模型。根据疲劳过程中材料强度退化的事实及其规律。分析了损伤临界值与循环应力水平之间的关系，给出了一般应力水平下疲劳损伤临界值的范围，对于随机疲劳问题，给出了损伤临界值的分布规律。     

Feedback minimization of first-passage failure of quasi non-integrable Hamiltonian systems

The non-linear stochastic optimal control of quasi non-integrable Hamiltonian systems for minimizing their first-passage failure is investigated. A controlled quasi non-integrable Hamiltonian system is reduced to an one-dimensional controlled diffusion process of averaged Hamiltonian by using the stochastic averaging method for quasi non-integrable Hamiltonian systems. The dynamical programming equations and their associated boundary and final time conditions for the problems of maximization of reliability and of maximization of mean first-passage time are formulated. The optimal control law is derived from the dynamical programming equations and the control constraints. The dynamical programming equations for maximum reliability problem and for maximum mean first-passage time problem are finalized and their relationships to the backward Kolmogorov equation for the reliability function and the Pontryagin equation for mean first-passage time, respectively, are pointed out. The boundary condition at zero Hamiltonian is discussed. Two examples are worked out to illustrate the application and effectiveness of the proposed procedure.     

Semi-Markov failure rates processes

Usually, a reliability function is defined by a failure rate which is a real function taking the non-negative real values. In this paper the failure rate is assumed to be a stochastic process with non-negative and right continuous trajectories. The reliability function is defined as an expectation of a function of that random process. Particularly, the failure rate defined by the semi-Markov processes is considered here. The theorems dealing with the renewal equations for the conditional reliability functions with a semi-Markov process as a failure rate are presented in this paper. A system of that kind of equations for the discrete state space semi-Markov process is applied for calculating the reliability function for the 3-states semi-Markov random walk. Using the introduced system of renewal equations for the countable state space, the reliability function for the Furry-Yule failure rate process is obtained.     

一种基于Fuzzy数学的计算机故障诊断新方法

提出了一种新的模糊诊断方法,建立了故障诊断的数学模型,并在计算机上实现了模糊诊断的仿真实验,并通过实例说明了这种方法有利于提高决策的准确性和可信度,在实际应用中是有效和可行的.     

单轴压缩条件下溶蚀礁灰岩细观变形破坏特征研究

礁灰岩的溶蚀对海洋工程和岛礁工程的稳定性有明显的影响.孔隙型溶蚀是礁灰岩常见的溶蚀方式.本文通过构建随机溶蚀孔洞的离散元模型,模拟孔洞型溶蚀礁灰岩的细观变形破坏特征,分析其变形破坏规律与裂隙演化特征.结果 表明,基于随机聚类算法构建的溶蚀礁灰岩离散元模型能够很好地模拟孔洞型溶蚀作用,且其变形破坏特征具有明显的规律;随着溶蚀率的增加,溶蚀礁灰岩单轴应力应变曲线由单峰型逐渐转变为双峰型或多峰型,破坏特征由脆性破坏逐渐转变为塑性破坏;随着溶蚀率的增加,礁灰岩单轴抗压强度和弹性模量都逐渐减小,抗压强度呈指数函数下降,弹性模量呈线性函数下降,而泊松比则表现为先增后降,说明试样在高溶蚀率时主要发生结构性破坏;随着溶蚀率增加,礁灰岩的宏观破裂面逐渐消失,由于溶蚀孔洞的相互作用,导致了起源于孔洞周围的裂隙开始萌生,并逐渐贯通,最终导致试样发生整体宏观破坏.本研究成果可为深入认识海洋工程和岛礁工程中溶蚀礁灰岩的变形破坏特征提供理论参考.     

Cytoprotective Mechanisms of DJ-1: Implications in Cardiac Pathophysiology

DJ-1 was originally identified as an oncogene product while mutations of the gene encoding DJ-1/PARK7 were later associated with a recessive form of Parkinson’s disease. Its ubiquitous expression and diversity of function suggest that DJ-1 is also involved in mechanisms outside the central nervous system. In the last decade, the contribution of DJ-1 to the protection from ischemia-reperfusion injury has been recognized and its involvement in the pathophysiology of cardiovascular disease is attracting increasing attention. This review describes the current and gaps in our knowledge of DJ-1, focusing on its role in regulating cardiovascular function. In parallel, we present original data showing an association between increased DJ-1 expression and antiapoptotic and anti-inflammatory markers following cardiac and vascular surgical procedures. Future studies should address DJ-1’s role as a plausible novel therapeutic target for cardiovascular disease.