A new approach to pointwise heat kernel upper bounds on doubling metric measure spaces

On doubling metric measure spaces endowed with a strongly local regular Dirichlet form, we show some characterisations of pointwise upper bounds of the heat kernel in terms of global scale-invariant inequalities that correspond respectively to the Nash inequality and to a Gagliardo–Nirenberg type inequality when the volume growth is polynomial. This yields a new proof and a generalisation of the well-known equivalence between classical heat kernel upper bounds and relative Faber–Krahn inequalities or localised Sobolev or Nash inequalities. We are able to treat more general pointwise estimates, where the heat kernel rate of decay is not necessarily governed by the volume growth. A crucial role is played by the finite propagation speed property for the associated wave equation, and our main result holds for an abstract semigroup of operators satisfying the Davies–Gaffney estimates.     

How to Obtain the Maximum Properties Flexibility of 3D Printed Ketoprofen Tablets Using Only One Drug-Loaded Filament?

The flexibility of dose and dosage forms makes 3D printing a very interesting tool for personalized medicine, with fused deposition modeling being the most promising and intensively developed method. In our research, we analyzed how various types of disintegrants and drug loading in poly(vinyl alcohol)-based filaments affect their mechanical properties and printability. We also assessed the effect of drug dosage and tablet spatial structure on the dissolution profiles. Given that the development of a method that allows the production of dosage forms with different properties from a single drug-loaded filament is desirable, we developed a method of printing ketoprofen tablets with different dose and dissolution profiles from a single feedstock filament. We optimized the filament preparation by hot-melt extrusion and characterized them. Then, we printed single, bi-, and tri-layer tablets varying with dose, infill density, internal structure, and composition. We analyzed the reproducibility of a spatial structure, phase, and degree of molecular order of ketoprofen in the tablets, and the dissolution profiles. We have printed tablets with immediate- and sustained-release characteristics using one drug-loaded filament, which demonstrates that a single filament can serve as a versatile source for the manufacturing of tablets exhibiting various release characteristics.     

A new characterization of the Berger sphere in complex projective space

We give a complete classification of Lagrangian immersions of homogeneous 3-manifolds (the Berger spheres, the Heisenberg group ${\text{Nil}}_3$, the universal covering of the Lie group $\text{PSL}(2,\mathbb{R})$ and the Lie group ${\text{Sol}}_3$) in 3-dimensional complex space forms. As a corollary, we get a new characterization of the Berger sphere in complex projective space.     

Mercury forms and their transformation in pyrite under weathering

Pyrite is considered to be the major carrier of mercury in coal. Here, the chemical characteristics of two natural pyrite samples of different weathering degrees were characterized by time-of-flight secondary ion mass spectrometry (TOF-SIMS). Thermal stability of Hg was also analyzed via temperature programmed desorption experiment (TPD). Characteristic ions such as S⁻, Fe⁺, FeS⁻, and FeS₂⁻ were detected on the surface of fresh pyrite. The release temperature of Hg ranged between 180°C and 300°C, and the characteristic peak of black HgS was recorded. In addition, abundant Fe₂O₃⁻, FeSO⁻, SO₄⁻, and HSO₄⁻ were detected on the surface of weathered pyrite, and the release temperature of Hg therein was mainly distributed at 260°C to 380°C and 520°C to 600°C, corresponding to the characteristic peaks of red HgS and HgSO₄, respectively. The results show that pyrite is acidified during weathering and that Hg forms in pyrite are transformed from the original state (HgS) to HgSO₄.     

Comment on the paper: H.-E. Hwang, P. Han, Theoretical analysis for surface tilt and translation detection based on speckle photography in the Fresnel domain, Opt. Commun. 282 (2009) 351-354

In a recent paper [H.-E. Hwang, P. Han, Opt. Commun. 282 (2009) 351] a speckle based metrology system is proposed which it is claimed provides significant advantages over existing systems. In this paper, we show that the discussion presented in [H.-E. Hwang, P. Han, Opt. Commun. 282 (2009) 351] is deficient, and that several of the statements made are incorrect and/or misleading.     

Generating functions for volume-preserving transformations

A general implicit solution for determining volume-preserving transformations in the n-dimensional Euclidean space is obtained in terms of a set of 2n generating functions in mixed coordinates. For n=2, the proposed representation corresponds to the classical definition of a potential stream function in a canonical transformation. For n=3, the given solution defines a more general class of isochoric transformations, when compared to existing methods based on multiple potentials. Illustrative examples are discussed both in rectangular and in cylindrical coordinates for applications in mechanical problems of incompressible continua. Solving exactly the incompressibility constraint, the proposed representation method is suitable for determining three-dimensional isochoric perturbations to be used in bifurcation theory. Applications in non-linear elasticity are envisaged for determining the occurrence of complex instability patterns for soft elastic materials.     

On an open problem of Sankaranarayanan

Let λ(n) be the n-th normalized Fourier coeficient of a holomorphic Hecke eigenform f(z) ∈ Sk(Γ) for the full modular group.In one of his papers,Sankaranarayanan mentioned that it is an open problem to give a non-trivial estimate for the sum of λ(n) over cubes,i.e.n x λ(n3).In this paper,we are able to use the analytic properties of symmetric power L-functions to solve his problem.More precisely,we prove that Σn≤zλ(n3) x(3/4 +ε),Σn≤zλ(n4) x(97+ε).     

Relativistic particles on quantum space-time

We discuss alternatives to the usual quantization of a relativistic particle which result in discrete spectra for position and time operators.     

Deformations of canonical singularities

We prove that small deformations of canonical singularities are canonical.