Turbulent air flows over developing wind waves in the air-sea boundary layer are numerically simulated without considering
wave breaking. Influences of wind waves on air flows are considered using a model of significant wave and surface roughness,
with a formula proposed for calculating the surface roughness. κ-ε model is adopted to simulate turbulent flows. The results
of the drag coefficient and turbulence characteristics agree well with the observations.
Project supported by the National Natural Science Foundation of China (Grant No. 19332010). 相似文献
Mesenchymal stem cells (MSCs) have been widely studied for their applications in stem cell-based regeneration. During myocardial infarction (MI), infiltrated macrophages have pivotal roles in inflammation, angiogenesis and cardiac remodeling. We hypothesized that MSCs may modulate the immunologic environment to accelerate regeneration. This study was designed to assess the functional relationship between the macrophage phenotype and MSCs. MSCs isolated from bone marrow and bone marrow-derived macrophages (BMDMs) underwent differentiation induced by macrophage colony-stimulating factor. To determine the macrophage phenotype, classical M1 markers and alternative M2 markers were analyzed with or without co-culturing with MSCs in a transwell system. For animal studies, MI was induced by the ligation of the rat coronary artery. MSCs were injected within the infarct myocardium, and we analyzed the phenotype of the infiltrated macrophages by immunostaining. In the MSC-injected myocardium, the macrophages adjacent to the MSCs showed strong expression of arginase-1 (Arg1), an M2 marker. In BMDMs co-cultured with MSCs, the M1 markers such as interleukin-6 (IL-6), IL-1β, monocyte chemoattractant protein-1 and inducible nitric oxide synthase (iNOS) were significantly reduced. In contrast, the M2 markers such as IL-10, IL-4, CD206 and Arg1 were markedly increased by co-culturing with MSCs. Specifically, the ratio of iNOS to Arg1 in BMDMs was notably downregulated by co-culturing with MSCs. These results suggest that the preferential shift of the macrophage phenotype from M1 to M2 may be related to the immune-modulating characteristics of MSCs that contribute to cardiac repair. 相似文献
The low power and narrow speed range remain bottlenecks that constrain the application of small-scale wind energy harvesting. This paper proposes a simple, low-cost, and reliable method to address these critical issues. A galloping energy harvester with the cooperative mode of vibration and collision (GEH-VC) is presented. A pair of curved boundaries attached with functional materials are introduced, which not only improve the performance of the vibration energy harvesting system, but also convert more mechanical energy into electrical energy during collision. The beam deforms and the piezoelectric energy harvester (PEH) generates electricity during the flow-induced vibration. In addition, the beam contacts and separates from the boundaries, and the triboelectric nanogenerator (TENG) generates electricity during the collision. In order to reduce the influence of the boundaries on the aerodynamic performance and the feasibility of increasing the working area of the TENG, a vertical structure is designed. When the wind speed is high, the curved boundaries maintain a stable amplitude of the vibration system and increase the frequency of the vibration system, thereby avoiding damage to the piezoelectric sheet and improving the electromechanical conversion efficiency, and the TENG works with the PEH to generate electricity. Since the boundaries can protect the PEH at high wind speeds, its stiffness can be designed to be low to start working at low wind speeds. The electromechanical coupling dynamic model is established according to the GEH-VC operating principle and is verified experimentally. The results show that the GEH-VC has a wide range of operating wind speeds, and the average power can be increased by 180% compared with the traditional galloping PEH. The GEH-VC prototype is demonstrated to power a commercial temperature sensor. This study provides a novel perspective on the design of hybrid electromechanical conversion mechanisms, that is, to combine and collaborate based on their respective characteristics.
We study a birth and death process $\{N_t\}_{t\ge0}$ in i.i.d. random environment, for which at each discontinuity, one particle might be born or at most $L$ particles might be dead. Along with investigating the existence and the recurrence criterion, we also study the law of large numbers of $\{N_t\}$. We show
that the first passage time can be written as a functional of an $L$-type branching process in random environment and a sequence of independent and exponentially distributed random variables. Consequently, an explicit velocity of the law of large numbers can be given. 相似文献
Most often, minimal repair is defined as a replacement of a failed item by an operable item that has the same distribution of the remaining lifetime as the failed one just prior a failure. This is the so‐called statistical minimal repair extensively explored in the literature. Another well‐known type of minimal repair takes into account the state of a system prior to a failure (the information‐based minimal repair). In this paper, we suggest the new type of minimal repair to be called conditional statistical minimal repair. Our approach goes further and deals with the corresponding minimal repair processes for systems operating in a random environment. Moreover, we also consider heterogeneous populations of items, which makes the model more realistic. Both of these aspects that affect the failure mechanism of items are studied. Environment is modeled by the nonhomogeneous Poisson shock process. Two models for the failure mechanism defined by the extreme shock model and the cumulative shock model, respectively, are considered. Some examples illustrating our findings are presented. 相似文献