双缆悬索桥空缆状态主缆抗滑安全性研究

为指导双缆悬索桥上下缆垂跨比的取值，明确双缆悬索桥施工阶段主缆抗滑稳定性，提出一种主缆在施工阶段空缆状态下的抗滑安全系数计算方法。基于上缆变下缆的主缆布置方式，通过双缆悬索桥成桥状态反推空缆状态主缆垂度，根据空缆状态下主缆线形为悬链线计算中塔塔顶鞍座处缆力及包角，并据此计算空缆状态抗滑安全系数。建立多塔悬索桥有限元模型对提出的公式进行验证，分析成桥状态上下缆垂跨比和桥梁跨度的取值对空缆到成桥状态主缆垂度变化以及抗滑安全系数的影响。结果表明，采用本文公式计算的双缆悬索桥空缆状态下抗滑安全系数精度较高；上下缆垂跨比对空缆状态主缆抗滑安全性影响较大，抗滑安全系数随着上下缆垂跨比差值的增大迅速减小；空缆状态主缆抗滑安全系数受跨度影响不大，其随跨度增大略有提高。在实际的双缆悬索桥初步设计过程中应考虑施工阶段主缆抗滑稳定性，选择适宜的上下缆垂跨比，采取措施提高施工阶段主缆抗滑安全性。     

Relative plus constructions

Let $h$ be a connective homology theory. We construct a functorial relative plus construction as a Bousfield localization functor in the category of maps of spaces. It allows us to associate to a pair $(X,H)$, consisting of a connected space $X$ and an $h$-perfect normal subgroup $H$ of the fundamental group ${\pi }_1\left(X\right)$, an $h$-acyclic map $X\to X_H^{+h}$ inducing the quotient by $H$ on the fundamental group. We show that this map is terminal among the $h$-acyclic maps that kill a subgroup of $H$. When $h$ is an ordinary homology theory with coefficients in a commutative ring with unit $R$, this provides a functorial and well-defined counterpart to a construction by cell attachment introduced by Broto, Levi, and Oliver in the spirit of Quillen’s plus construction. We also clarify the necessity to use a strongly $R$-perfect group $H$ in characteristic zero.     

基于OBE和EHS理念的制药过程安全与环保课程体系建设

“制药过程安全与环保”为制药工程专业本科生必修核心课程，但其课程体系不完善，基于OBE和EHS理念，从课程目标、课程内容、课程思政、教材、教学方法、课程考核与评价方法等方面对该课程进行了建设和完善，取得了一些创新性成果与经验，制定了教学目标，创新性地设置了课程内容，开展了课程思政，主编了教材，提出了适宜的教学方法，建立了课程考核与评价方法，可以为全国其他高等院校类似课程的教学与建设提供有益的借鉴。     

Very weak solutions of the Dirichlet problem for the two dimensional Monge-Ampère equation

In this paper, infinitely many $C^{1,\theta }(\theta <\frac{1}{5})$ very weak solutions to the Dirichlet problem for the two dimensional Monge-Ampère equation are obtained from inductively applying the Nash-Kuiper construction of subsolutions satisfying the boundary condition. The initial subsolutions are generated from the solutions of some Possion equations. The inductive construction is then attained by successively adding compactly supported deficit matrixes.