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81.
82.
T. Jeanmaire C. Brondino Y. Hervaud B. Boutevin 《Phosphorus, sulfur, and silicon and the related elements》2013,188(10):2331-2343
Ce mémoire décrit la synthèse de phosphonates comportant une chaîne perfluorée. Ces composés sont obtenus par la télomérisation d'allylphosphonates de dialkyle en présence d'un agent de transfert fluoré de type mercaptan. Ensuite, nous employons deux méthodes de déalkylation menant sélectivement soit au monoacide soit au diacide phosphonique. Tous ces produits comprenant une extrémité de chaîne phosphonée, sous forme acide ou ester, ont été caractérisés et leur adhésion respective sur des plaques d'acier est étudiée. Ces tests montrent que le monoacide phosphonique est un excellent promoteur d'adhésion et qu'il est aussi efficace que le diacide. This article describes the synthesis of phosphonic derivatives bearing a perfluorinated chain. These compounds have been synthetized by telomerization of dialkyl allylphosphonate with a fluorinated transfer agent type mercaptan. Then two methods of dealkylation leading selectively were used to mono or to diacid phosphonic moieties. All the products bearing phosphonic end-groups, more or less acidic, have been characterized and their own adhesion on steel plates is studied. These tests show that phosphonic monoacid is an excellent adhesion promoter on steel, as efficient as the diacid compound. 相似文献
83.
A new class of diarylsulfones, in which tetrahydrobenzazepine comprises one of the aromatic moieties, has been synthesized via the acid‐catalyzed rearrangement of several substituted benzazepinesulfonamides. The rearrangement is normally ortho but in at least one case a para isomer is also formed. Sulfones of this type have been shown to possess potent anti‐HIV activity. 相似文献
84.
A multicommutated flow analysis (MCFA) system constructed of microsolenoid valves and pumps offering simultaneous determination of activity of acid phosphatase (ACP) and alkaline phosphatase (ALP) in human serum samples has been developed. The MCFA system is based on optoelectronic flow-through detector made of two light emitting diodes and operating according to paired emitter detector diode (PEDD) principle. This photometric PEDD device has been dedicated for detection of p-nitrophenol (NP) generated in the course of enzymatic hydrolysis of p-nitrophenyl phosphate and optimized for the determination of NP in human serum samples. The developed PEDD-based MCFA system allows independent optimization of conditions for reaction and detection steps of photometric ACP and ALP bioassays. Moreover, it allows elimination of photometric interferences from serum matrix components according to two-points kinetic mode of measurement. The single measurement cycle takes 12 min, consists of four measurements (two for each phosphoesterase) and enables determination of serum ACP and ALP activities at physiological and pathological levels. The real analytical utility of the developed MCFA system has been confirmed by analysis of control sera as well as real human serum samples from healthy persons and oncological patients. 相似文献
85.
The performance enhancement of 3D-printed electrode comprised of polylactic acid (PLA) and graphite (Gr) doped with graphene oxide (GO) was studied to detect five heavy metal ions in trace level. The pretreatment of PLA/Gr/GO electrode with potential cycling in H2SO4 solution achieved the most sensitive response. The characteristics of the composite electrodes were verified using XPS, FE-SEM, EDXS, Raman, and impedance spectroscopy. The experimental variables affecting the response current were optimized with respect to pH, deposition time, ratio of PLA/Gr/GO, and supporting electrolytes. The pretreated 3D-PLA/Gr/GO electrode showed a wide dynamic range from 0.5 ppb to 1.0 ppm with low detection limits of 0.039–0.13 ppb. The reliability of the PLA/Gr/GO electrode was evaluated by analyzing the reference samples of European Reference Materials. 相似文献
86.
Huixin Wang Dr. Michael G. Leeming Dr. Junming Ho Dr. William A. Donald 《Chemistry (Weinheim an der Bergstrasse, Germany)》2019,25(3):823-834
Predicting the fragmentation patterns of proteins would be beneficial for the reliable identification of intact proteins by mass spectrometry. However, the ability to accurately make such predictions remains elusive. An approach to predict the specific cleavage sites in whole proteins resulting from collision-induced dissociation by use of an improved electrostatic model for calculating the proton configurations of highly-charged protein ions is reported. Using ubiquitin, cytochrome c, lysozyme and β-lactoglobulin as prototypical proteins, this approach can be used to predict the fragmentation patterns of intact proteins. For sufficiently highly charged proteins, specific cleavages occur near the first low-basicity amino acid residues that are protonated with increasing charge state. Hybrid QM/QM′ (QM=quantum mechanics) and molecular dynamics (MD) simulations and energy-resolved collision-induced dissociation measurements indicated that the barrier to the specific dissociation of the protonated amide backbone bond is significantly lower than competitive charge remote fragmentation. Unlike highly charged peptides, the protons at low-basicity sites in highly charged protein ions can be confined to a limited sequence of low-basicity amino acid residues by electrostatic repulsion, which results in highly specific fragmentation near the site of protonation. This research suggests that the optimal charge states to form specific sequence ions of intact proteins in higher abundances than the use of less specific ion dissociation methods can be predicted a priori. 相似文献
87.
88.
Application of HPLC-Thermospray Flame AAS: Interaction Between Heavy Metals and Duckweed Chlorophyll
Thermospray nebulizer interfaced HPLC-Flame AAS was used to study the effect of heavy metals (Al, Cd, Cu, Hg and Zn) on the chlorophylls of duckweed. Flame AAS was used as a metal specific detector of HPLC. Study indicated that heavy metals promote the degradation of chlorophylls. No evidence of direct replacement of central magnesium with heavy metals was found. 相似文献
89.
《Comptes Rendus Chimie》2016,19(10):1194-1202
The current transition from petrochemical resources to biomass-derived platform molecules is in great demand for the development of synergies, scientific innovations and breakthroughs, and steep changes in the infrastructure of chemical industries. This article is focused on new opportunities for the production of biofuel additives from bioglycerol, which is obtained as waste and/or by-product from the current biodiesel industries. Here, we summarize the recent relevant processes for the production of biofuel additives from bioglycerol over various acid catalysts in two different pathways: (i) the esterification of bioglycerol with acetic acid, levulinic acid and other acids, and (ii) the acetalization of bioglycerol with acetone, furfural, benzaldehyde and other carbonyl compounds. It is evident that the synthesis of biofuel additives through esterfication and acetalization of bioglycerol is an important research area with imperative prospects for industrial applications. 相似文献
90.
M. Gaboyard Y. Hervaud B. Boutevin 《Phosphorus, sulfur, and silicon and the related elements》2013,188(4):877-891
Long-chain dialkyl alkylphosphonates were synthesized by radical addition of dialkyl hydrogenphosphonates onto alkenes in presence of di(t-butyl) peroxide. This synthetic route leads to high yields between 94 and 97%. We performed chemical modifications of these phosphonates in order to obtain acidic derivatives. The structure of these compounds was characterized by NMR analyses and mass spectroscopy. We also studied their thermal behaviour and various crystalline phases were put in evidence by differential scanning calorimetry and optical microscopy. The thermal stability of these compounds was compared by thermogravimetric analyses. 相似文献