996.
We measured MR images of the liver of Long-Evans Cinnamon (LEC) rats with pathologic correlation and assessed the effectiveness of MR imaging (MRI) for diagnosis of noncancerous hepatic lesions. T
1- and T
2-weighted images of their livers were obtained, and the dynamic and delayed studies after intravenous gadolinium injection were also performed. Cholangiofibrosis showed low signal intensity on T
1-weighted images and high signal intensity on T
2-weighted images. The T
2 relaxation time of cholangiofibrosis was significantly prolonged (
p < .01), and the signal intensity ratio of this lesion to muscle on T
1-weighted images was significantly lower than that of normal liver parenchyma to muscle (
p < .01). The lesion was enhanced immediately after gadolinium injection and the enhancement was prolonged. Among three cases of peliosis hepatis identified, one showed heterogeneous intensities on both T
1- and T
2-weighted images and the other two showed similar intensity pattern to cholangiofibrosis. The characteristic MR appearance of cholangiofibrosis may be useful to distinguish it from hepatocellular carcinoma (HCC).
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