全文获取类型
收费全文 | 116621篇 |
免费 | 29711篇 |
国内免费 | 21570篇 |
专业分类
化学 | 77141篇 |
晶体学 | 1461篇 |
力学 | 7820篇 |
综合类 | 323篇 |
数学 | 14008篇 |
物理学 | 67149篇 |
出版年
2024年 | 479篇 |
2023年 | 1582篇 |
2022年 | 1754篇 |
2021年 | 2129篇 |
2020年 | 2756篇 |
2019年 | 3141篇 |
2018年 | 2873篇 |
2017年 | 3286篇 |
2016年 | 4209篇 |
2015年 | 4295篇 |
2014年 | 4704篇 |
2013年 | 7030篇 |
2012年 | 8090篇 |
2011年 | 9615篇 |
2010年 | 11647篇 |
2009年 | 11737篇 |
2008年 | 6005篇 |
2007年 | 5236篇 |
2006年 | 4814篇 |
2005年 | 4711篇 |
2004年 | 5096篇 |
2003年 | 4096篇 |
2002年 | 3881篇 |
2001年 | 3985篇 |
2000年 | 3034篇 |
1999年 | 3426篇 |
1998年 | 2832篇 |
1997年 | 2629篇 |
1996年 | 2973篇 |
1995年 | 3307篇 |
1994年 | 3286篇 |
1993年 | 3224篇 |
1992年 | 2803篇 |
1991年 | 2404篇 |
1990年 | 2019篇 |
1989年 | 2055篇 |
1988年 | 1989篇 |
1987年 | 1253篇 |
1986年 | 1315篇 |
1985年 | 950篇 |
1984年 | 1024篇 |
1982年 | 920篇 |
1981年 | 767篇 |
1980年 | 781篇 |
1979年 | 528篇 |
1978年 | 530篇 |
1977年 | 633篇 |
1976年 | 1042篇 |
1973年 | 436篇 |
1972年 | 532篇 |
排序方式: 共有10000条查询结果,搜索用时 46 毫秒
31.
32.
Qin Yin Shou-Guo Wang Xiao-Wei Liang De-Wei Gao Jun Zheng Shu-Li You 《Chemical science》2015,6(7):4179-4183
An organocatalytic asymmetric chlorinative dearomatization of naphthols was realized for the first time, providing chiral naphthalenones with a Cl-containing all-substituted stereocenter in excellent yields and enantioselectivity (up to 97% yield and 96% ee). The reaction features mild reaction conditions, good tolerance of diverse functional groups and simple reaction operation. 相似文献
33.
量子自旋液体是最近几年刚被人们证实除铁磁体、反铁磁体之外的第三种磁性类型,因其有望解释高温超导的运行机制、改变计算机硬盘信息存储方式而在物理、材料等领域备受关注。自旋阻挫作为量子自旋液体的最小单元可能是解开量子自旋液体诸多问题的钥匙,所以在磁学、电学研究领域再一次成为人们研究的热点。基于文献报道的三核铜配合物[Cu3(μ3-OH)(μ-OPz)3(NO3)2(H2O)2]·CH3OH(1),我们合成了三维金属有机框架配合物{[Ag(HOPz)Cu3(μ3-OH)(NO3)3(OPz)2Ag(NO3)]·6H2O}n(2)(HOPz=甲基(2-吡嗪基)酮肟),并从自旋阻挫的角度对二者磁性质进行对比和详细分析。磁化率数据表明自旋间有很强的反铁磁相互作用和反对称交换。通过包含各向同性和反对称交换的哈密顿算符对两者磁学数据进行拟合并研究其磁构关系,所获最佳拟合参数为:配合物1:Jav=-426 cm^-1,g⊥=1.83,g∥=2.00;配合物2:Jav=-401 cm^-1,g⊥=1.85,g∥=2.00。 相似文献
34.
35.
36.
Richiro Ushimaru Zhang Chen Houyuan Zhao Po-hsun Fan Prof. Dr. Hung-wen Liu 《Angewandte Chemie (Weinheim an der Bergstrasse, Germany)》2020,132(9):3586-3590
Albomycin δ2 is a sulfur-containing sideromycin natural product that shows potent antibacterial activity against clinically important pathogens. The l -serine-thioheptose dipeptide partial structure, known as SB-217452, has been found to be the active seryl-tRNA synthetase inhibitor component of albomycin δ2. Herein, it is demonstrated that AbmF catalyzes condensation between the 6′-amino-4′-thionucleoside with the d -ribo configuration and seryl-adenylate supplied by the serine adenylation activity of AbmK. Formation of the dipeptide is followed by C3′-epimerization to produce SB-217452 with the d -xylo configuration, which is catalyzed by the radical S-adenosyl-l -methionine enzyme AbmJ. Gene deletion suggests that AbmC is involved in peptide assembly linking SB-217452 with the siderophore moiety. This study establishes how the albomycin biosynthetic machinery generates its antimicrobial component SB-217452. 相似文献
37.
Mass concentration and isotopic values δ13C and 14C are presented for the water-insoluble refractory carbon(WIRC) component of total suspended particulates(TSP),collected weekly during 2003,as well as from October 2005 to May 2006 at the WMO-GAW Mt.Waliguan(WLG) site.The overall average WIRC mass concentration was(1183±120)ng/m3(n = 79),while seasonal averages were 2081 ±1707(spring),454±205(summer),650±411(autumn),and 1019±703(winter) ng/m3.Seasonal variations in WIRC mass concentrations were consistent with black carbon measurements from an aethalometer,although WIRC concentrations were typically higher,especially in winter and spring.The δ13C PDB value(-25.3 ± 0.8)%.determined for WIRC suggests that its sources are C3 biomass or fossil fuel combustion.No seasonal change in δ13C PDB was evident.The average percent Modern Carbon(pMC) for 14C in WIRC for winter and spring was(67.2 ± 7.7)%(n = 29).Lower pMC values were associated with air masses transported from the area east of WLG,while higher pMC values were associated with air masses from the Tibetan Plateau,southwest of WLG.Elevated pMC values with abnormally high mass concentrations of TSP and WIRC were measured during a dust storm event. 相似文献
38.
The biodegradability of phtalic acid esters in marine and freshwater environments was characterized by their binding free energy with corresponding degrading enzymes. According to comprehensive biodegradation effects weights, the binding free energy values were converted into dimensionless efficacy coefficient using ratio normalization method. Then, considering comprehensive dual biodegradation effects value and the structural parameters of PAEs in both marine and freshwater environments, a 3D-QSAR pharmacophore model was constructed, five PAE derivatives (DBP−COOH, DBP−CHO, DBP−OH, DINP−NH2, and DINP−NO2) were screened out based on their environmental friendliness, functionality and stability. The prediction of biodegradation effects on five PAE derivatives by biodegradation models in marine and freshwater environment increased by 15.90 %, 15.84 %, 27.21 %, 12.33 %, and 8.32 %, and 21.57 %, 15.21 %, 20.99 %, 15.10 %, and 9.74 %, respectively. By simulating the photodegradation path of the PAE derivative molecular, it was found that DBP−OH can generate .OH and provides free radicals for the photodegradation of microplastics in the environment. 相似文献
39.
40.
在中国科学技术大学夏季学期的研究型实验课程"化学科研基础训练"中开设"壳聚糖的制备与表征"综合实验,以龙虾壳为原料,通过除蛋白、脱盐、脱色、脱乙酰等一系列反应,制备得到目标产物壳聚糖。运用红外光谱、核磁共振仪、黏度法、滴定等对产品的结构及性能进行表征。 相似文献