平面粘性流体扰动与哈密顿体系

通过变分原理,将哈密顿体系的理论引入到平面粘性流体扰动的问题中,导出一套哈密顿算子矩阵的本征函数向量展开求解问题的方法。基于直接法求解流体力学基本方程,导出流场一般特征关系,通过本征值的求解及本征向量的叠加,得到波扰动解,继可分析流场端部效应。从而在该领域用在哈密顿体系下辛几何空间中研究问题的方法代替了传统在拉格朗日体系欧几里德空间分析问题的方法。为流体力学的研究提供一条新途径。     

Collagen-EGCG Combination Synergistically Prevents UVB-Induced Skin Photoaging in Nude Mice

Ultraviolet (UV) radiation is a major cause of skin photoaging through generating excessive oxidative stress and inflammation. One of the strategies is to use photo-chemoprotectors, such as natural products with antioxidant and anti-inflammatory properties, to protect the skin from photo damage. The present study investigates the photoprotective potentials of topical administration of unhydrolyzed collagen, epigallocatechin gallate (EGCG), and their combination against ultraviolet B (UVB)-induced photoaging in nude mice. It is found that both the solo and combined pretreatments could recover UVB-induced depletion of antioxidative enzymes, including superoxide dismutase and glutathione peroxidase (GSH-Px), as well as an increase of lipid peroxide malondialdehyde and inflammatory tumor necrosis factor-α. Meanwhile, the UVB-stimulated skin collagen degradation is attenuated significantly with drug treatments, which is evidenced by expression analysis of matrix metalloproteinase-1 and hydroxyproline. Additionally, the mouse skin histology shows that the drug-pretreated groups possess decreased epidermis thickness and normal collagen fiber structure of the dermis layer. These results demonstrate that both EGCG and collagen can protect the skin against UVB-induced skin photoaging. Synergistically, the combination of them shows the maximum prevention to skin damage, showing its potential in the application of anti-photoaging formulation products.