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981.
Liang Chen Yu Fan Jieru Qiu Dr. Régis Laurent Jin Li Prof. Dr. Jérôme Bignon Prof. Dr. Serge Mignani Prof. Dr. Anne-Marie Caminade Prof. Dr. Xiangyang Shi Prof. Dr. Jean-Pierre Majoral 《Chemistry (Weinheim an der Bergstrasse, Germany)》2020,26(26):5903-5910
First-in-class CuII and AuIII metaled phosphorus dendrons were synthesized and showed significant antiproliferative activity against several aggressive breast cancer cell lines. The data suggest that the cytotoxicity increases with reducing length of the alkyl chains, whereas the replacement of CuII with AuIII considerably increases the antiproliferative activity of metaled phosphorus dendrons. Very interestingly, we found that the cell death pathway is related to the nature of the metal complexed by the plain dendrons. CuII metaled dendrons showed a potent caspase-independent cell death pathway, whereas AuIII metaled dendrons displayed a caspase-dependent apoptotic pathway. The complexation of plain dendrons with AuIII increased the cellular lethality versus dendrons with CuII and promoted the translocation of Bax into the mitochondria and the release of Cytochrome C (Cyto C). 相似文献
982.
Ultrathin Mn Doped Ni-MOF Nanosheet Array for Highly Capacitive and Stable Asymmetric Supercapacitor
Dengchao Zheng Hao Wen Xun Sun Xin Guan Jie Zhang Wenli Tian Hao Feng Dr. Hongjing Wang Prof. Yadong Yao 《Chemistry (Weinheim an der Bergstrasse, Germany)》2020,26(71):17149-17155
In this study, we demonstrate that an Mn-doped ultrathin Ni-MOF nanosheet array on nickel foam (Mn0.1-Ni-MOF/NF) serves as a highly capacitive and stable supercapacitor positive electrode. The Mn0.1-Ni-MOF/NF shows an areal capacity of 6.48 C cm−2 (specific capacity C: 1178 C g−1) at 2 mA cm−2 in 6.0 m KOH, outperforming most reported MOF-based materials. More importantly, it possesses excellent cycle stability to maintain 80.6 % capacity after 5000 cycles. An asymmetric supercapacitor device utilizing Mn0.1-Ni-MOF/NF as the positive electrode and activated carbon as the negative electrode attains a high energy density of 39.6 Wh kg−1 at 143.8 Wkg−1 power density with a capacitance retention of 83.6 % after 5000 cycles. 相似文献
983.
Zhuangjun Fan 《物理化学学报》2020,36(2):1907017-0
正超级电容器是一种新型的绿色储能装置,具有功率密度高、循环寿命长、充放电速度快、可靠性高、绿色环保等特性,在移动通讯、航空航天、电动汽车和国防等领域有着巨大的应用潜力。近年来,随着超级电容器研究的不断深入、相关技术产业的快速发展,其应用领域正在不断的扩展、市场前景十分广阔1,2。电极材料是超级电容器的关键所在,它决定着该储能器件的主要性能指标,如 相似文献
984.
Jing He Mohan Yu Maofu Pang Yanqing Fan Zhe Lian Dr. Ying Wang Prof. Wenguang Wang Prof. Yajun Liu Prof. Hua Jiang 《Chemistry (Weinheim an der Bergstrasse, Germany)》2022,28(13):e202103832
Structural designs combining cycloparaphenylenes (CPPs) backbone with planar chiral [2.2]paracyclophane ([2.2]PCP) lead to optical-active chiral macrocycles with intriguing properties. X-ray crystal analysis revealed aesthetic necklace-shaped structures and size-dependent packages with long-range channels. The macrocycles exhibit unique photophysical properties with high fluorescence quantum yield of up to 82 %, and the fluorescent color varies with ring size. In addition, size-dependent chiroptical properties with moderately large CPL dissymmetry factor of 10−3 and CPL brightness in the range of 30–40 M−1 cm−1 were observed. 相似文献
985.
In this report, CuO/MoS2 composites were successfully prepared by the hydrothermal method where nano‐sized CuO was uniformly distributed on the surface of hierarchical MoS2 substrates (CuO/MoS2 composites). Their physicochemical properties and catalytic performance in ammonium perchlorate (AP) decomposition were investigated and characterized by XRD, SEM, TEM, BET, XPS, TG/DSC and combustion measurement. The results showed that it could decrease AP decomposition temperature at high decomposition stage from 416.5 °C to 323.5 °C and increase the heat release from 378 J/g (pure AP) to 1340 J/g (AP with catalysts), which was better than pure CuO nanoparticles (345.5 °C and 1046 J/g). Meanwhile, it showed excellent performance in combustion reaction either in N2 or air atmosphere. The results obtained by photocurrent spectra, photoluminescence spectra and time‐resolved fluorescence emission spectra indicated that loading CuO mediated the generation rate and combination rate of electrons and holes, thus tuning the catalytic performance on AP decomposition. This study proved that employing the supports that can synergistically interact with CuO is an efficient strategy to enhance the catalytic performance of CuO. 相似文献
986.
Yanni Lv Xianpeng Shi Jia Fu Qianqian Jia Yuanyuan Lin Hongying Wang Xin Yang Shengli Han 《Biomedical chromatography : BMC》2019,33(9)
Marsdenia tenacissima, or Tongguanteng in Chinese, is a traditional Chinese herb and has a broad application in clinical practice for its pharmacological effects of treating asthma, pneumonia, tonsillitis, pharyngitis tumors, etc. However, few studies have reported the screening of the active components of this medicine for tumor therapy. In this work, a two‐dimensional analytical system was developed to screen antagonists of epidermal growth factor receptor (EGFR) from M. tenacissima. A fraction was retained on the EGFR cell membrane chromatography (CMC) column, separated and identified as tenacissoside G (TG), tenacissoside H (TH) and tenacissoside I (TI) by two‐dimensional HPLC–IT–TOF–MS. Molecular docking and 3‐(4,5‐dimethyl‐2‐thiazolyl)‐2,5‐diphenyl‐2‐H‐tetrazolium bromide (MTT) assay were carried out to assess the activity of TS (including TG, TH and TI). Molecular docking results showed that the binding mode of TS on EGFR is similar to that of gefitinib. The MTT assay demonstrated that gefitinib and TS (especially TI) could inhibit the growth of EGFR highly expressed cell lines in a dose‐dependent manner in the range of 5–50 μmol/L. In conclusion, the two‐dimensional EGFR/CMC–HPLC–IT–TOF–MS system could be a useful approach in drug discovery from traditional Chinese medicines for searching for potential antitumor candidates. 相似文献
987.
Mathematische Zeitschrift - In this note, we construct non-isotrivial families of curves of genus $$g\ge 2$$ , where the rank of the unitary summand contained in the Hodge bundle can be as large as... 相似文献
988.
Acta Mathematicae Applicatae Sinica, English Series - A graph is NIC-planar if it admits a drawing in the plane with at most one crossing per edge and such that two pairs of crossing edges share at... 相似文献
989.
Three multinuclear Cu (II), Zn (II) and Cd (II) complexes, [Cu2(L)(μ‐OAc)]·CHCl2 ( 1 ), [Zn2(L)(μ‐OAc)(H2O)]·3CHCl3 ( 2 ) and [{Cd2(L)(OAc)(CH3CH2OH)}2]·2CH3CH2OH ( 3 ) with a single‐armed salamo‐like dioxime ligand H3L have been synthesized, and characterized by FT‐IR, UV–vis, X‐ray crystallography and Hirshfeld surfaces analyses. The ligand H3L has a linear structure and C‐H···π interactions between the two molecules. The complex 1 is a dinuclear Cu (II) complex, Cu1 and Cu2 are all five‐coordinate possessing distorted square pyramidal geometries. The complex 2 also forms a dinuclear Zn (II) structure, and Zn1 and Zn2 are all five‐coordinate bearing distorted trigonal bipyramidal geometries. The complex 3 is a symmetrical tetranuclear Cd (II) complex, and Cd1 is a hexa‐coordinate having octahedral configuration and Cd2 is hepta‐coordinate with a pentagonal bipyramidal geometry, and it has π···π interactions inside the molecule. In addition, fluorescence properties of the ligand and its complexes 1 – 3 have also been discussed. 相似文献
990.
Newly established in 2018, the UK Research and Innovation (UKRI) strengthens the strategic coordination of the UK research and innovation system by bringing together seven Research Councils, Research England, and Innovate UK. Through its nine organizations, UKRI funds multidisciplinary and interdisciplinary research in a number of priority areas. It also runs the Strategic Priorities Fund to support multidisciplinary and interdisciplinary research in strategic areas identified by government policies as well as the Global Challenges Research Fund to promote challenge-led interdisciplinary research needed by developing countries. The UKRI makes significant efforts to engage stakeholders in the development, design, and implementation of multidisciplinary and interdisciplinary programs. It has also developed a range of mechanisms to improve the evaluation of multidisciplinary and interdisciplinary projects. Chinese science and innovation funding agencies could draw upon the UKRI experience from four aspects to advance interdisciplinary research in China. 相似文献