全文获取类型
收费全文 | 4668篇 |
免费 | 162篇 |
国内免费 | 21篇 |
专业分类
化学 | 3386篇 |
晶体学 | 36篇 |
力学 | 117篇 |
数学 | 624篇 |
物理学 | 688篇 |
出版年
2023年 | 28篇 |
2022年 | 26篇 |
2021年 | 120篇 |
2020年 | 86篇 |
2019年 | 73篇 |
2018年 | 64篇 |
2017年 | 69篇 |
2016年 | 170篇 |
2015年 | 119篇 |
2014年 | 127篇 |
2013年 | 289篇 |
2012年 | 358篇 |
2011年 | 393篇 |
2010年 | 213篇 |
2009年 | 163篇 |
2008年 | 331篇 |
2007年 | 310篇 |
2006年 | 263篇 |
2005年 | 296篇 |
2004年 | 221篇 |
2003年 | 191篇 |
2002年 | 162篇 |
2001年 | 64篇 |
2000年 | 58篇 |
1999年 | 37篇 |
1998年 | 43篇 |
1997年 | 31篇 |
1996年 | 62篇 |
1995年 | 30篇 |
1994年 | 31篇 |
1993年 | 47篇 |
1992年 | 27篇 |
1991年 | 31篇 |
1990年 | 36篇 |
1989年 | 28篇 |
1988年 | 25篇 |
1987年 | 31篇 |
1986年 | 15篇 |
1985年 | 31篇 |
1984年 | 23篇 |
1983年 | 14篇 |
1982年 | 21篇 |
1981年 | 16篇 |
1980年 | 14篇 |
1979年 | 16篇 |
1978年 | 9篇 |
1977年 | 6篇 |
1975年 | 4篇 |
1974年 | 7篇 |
1973年 | 5篇 |
排序方式: 共有4851条查询结果,搜索用时 359 毫秒
81.
Simple and rapid micellar electrokinetic capillary chromatographic method for simultaneous determination of four antiepileptics in human serum 总被引:1,自引:0,他引:1
A very rapid and simple MEKC method was developed for the simultaneous determination of four antiepileptic drugs, ethosuximide (Etho), primidone (Pri), phenytoin (Pht) and carbamazepine (Cbz) in human serum. Sample analysis required only 100 microL of human serum which only needed to be centrifuged, decanted and combined with the running buffer [5.3 mM Na(2)HPO(4)/3.2 mM borax buffer (pH 9.5) containing 55 mM SDS and 3.5% (v/v) acetone]. The analysis was performed in only 10 min into fused-silica capillaries (57 cm total length with 50 microm i.d. and 50 cm to the detector) using the MEKC methodology with diode-array detection at 220 nm. The calibration graphs were established for ethoximide, primidone, phenytoin and carbamazepine between 0 and 20 mg/L. Recoveries were between 85 and 87%. The simplicity of the proposed methodology makes it suitable for routine clinical use, especially for epileptic patients on polytherapy. 相似文献
82.
83.
Ródenas-Torralba E Cava-Montesinos P Morales-Rubio A Cervera ML De La Guardia M 《Analytical and bioanalytical chemistry》2004,379(1):83-89
The aim of this study is to show the advantages of the emerging multicommutation methodology based on the use of solenoid valves for Te determination in milk by hydride generation atomic fluorescence spectrometry (HG-AFS). The delivery of a series of alternating sequential insertions of small volumes of samples and reagents gives rise to new hydrodynamic processes and exciting analytical potentials by controlling the time of flow through the on/off-switched solenoid valves. This drastically reduces the reagent consumption by a factor of 4 and the generation of effluents (590 mL h–1 instead of 750 mL h–1 generated by the continuous-mode measurement) and also provides an improvement in the laboratory productivity by an increase of the sample throughput (85 h–1 compared to 20 h–1 found in the continuous mode). So, multicommutation is an environmentally and economically sustainable alternative to the methodology based on continuous measurements. The multicommutation-based method developed was applied to tellurium determination in commercially available milk samples; a calibration range of 0.0–0.5 ng mL–1 and a detection limit of 0.20 ng L–1 with average relative standard deviation of 2.1% were found. Comparable results were obtained for a series of samples using both continuous and multicommutation HG-AFS modes. 相似文献
84.
Fuentes-Cabrera M Nicholson DM Sumpter BG Widom M 《The Journal of chemical physics》2005,123(12):124713
We investigate the possibility of tailoring the electronic properties of isoreticular metal-organic materials by replacing the metal atom in the metal-organic cluster and by doping. The electronic structure of M-IRMOF1, where IRMOF1 stands for isoreticular metal-organic framework 1 and M = Be, Mg, Ca, Zn, and Cd, was examined using density-functional theory. The results show that these materials have similar band gaps (ca. 3.5 eV) and a conduction band that is split into two bands, the lower of which has a width that varies with metal substitution. This variation prompted us to investigate whether doping with Al or Li could be used to tailor the electronic properties of the Zn-IRMOF1 and Be-IRMOF1 materials. It is shown that replacing one metal atom with Al can effectively be used to create IRMOFs with different metallic properties. On the other hand, adding Li produces structural changes that render this approach less suitable. 相似文献
85.
Lhiaubet-Vallet V Sarabia Z Boscá F Miranda MA 《Journal of the American Chemical Society》2004,126(31):9538-9539
A remarkable stereodifferentiation has been observed in the interaction between the excited triplet state of carprofen (CP) and human serum albumin (HSA). Time-resolved measurements using laser flash photolysis reveal the presence of two components with different lifetimes in triplet decay. This is explained by complexation of CP to the two possible HSA binding sites. The shorter-lived components are ascribed to the CP/HSA complexes in site I, where stereodifferentiation is more important (tauR/tauS ca. 4). This is correlated with formation of a dehalogenated photoproduct upon steady-state photolysis. 相似文献
86.
Spectrofluorimetric characteristics of pindolol have been investigated with the aim of using this technique for analytical determinations. Other monosubstituted indole derivatives, 4-methoxy and 5-methoxyindole, have been also studied for comparative purposes. Corrected excitation and emission wavelengths in different solvents are reported and the effect of solvent on the Stokes shifts of these compounds has been analysed using the Lippert equation. In addition, the Stokes shift of pindolol has been determined in dioxan-water solvent mixtures and the presence of specific solvent effects is discussed. The fluorescence of pindolol is pH dependent, the quantum yields determined in water are lower than those in other solvents. With respect to the sensitivity, it has been found that the detection limits in aqueous solutions are improved in the presence of beta and methyl-beta-cyclodextrin. Finally, a fluorimetric analysis of the interaction between pindolol and different cyclodextrins has been carried out in order to determine the apparent stability constants of the complexes and the thermodynamic parameters associated to complexation. 相似文献
87.
Fernando Lazaro M. Dolores Luque de Castro Miguel Valcarcel 《Fresenius' Journal of Analytical Chemistry》1988,332(7):809-812
Summary A fast and inexpensive fluorimetric method for the determination of total aflatoxins (B1, B2, G1, and G2) in food of use in screening numerous samples suspectedly containing these substances is proposed. The sensitivity of the method (determination range between 0.5 and 200.0 ng ml–1) allows these analytes to be detected at concentrations well below legal limits; hence, separation-detection techniques such as HPLC need only be used with samples in which these compounds are found to occur. The method has been applied to maize, peanut and tapioca samples, obtaining average recoveries of 100.9 with deviations of ±5% with respect to 100% recovery.
Fluorometrische Bestimmung von Aflatoxinen durch Fließinjektionsanalyse相似文献
88.
Jose L. Zurita Maria L. G. de Soria Miguel A. Postigo Miguel Katz 《Journal of solution chemistry》1987,16(2):163-170
Densities, viscosities, enthalpies, vapor-liquid equilibria, and surface tensions were determined at 25°C for the 2-propanol+dichloromethane system. From the experimental results excess volumes, viscosities, enthalpies, Gibbs energies, and excess surface tensions were calculated. An attempt has been made to explain the observed deviations from ideal behavior on the basis of intermolecular interactions. 相似文献
89.
Luque Ruiz I García GC Gómez-Nieto MA 《Journal of chemical information and computer sciences》2004,44(6):1903-1911
The increase in the size and complexity of chemical databases necessitates the proposal and development of efficient methods of classification and recovery of information, which supposes proposal of a model of classification of database records and the use of a compatible model of screening for inspection of clusters and recovery of the molecules that satisfy the search criterion. The cycle graphs model based on consideration of all the cycles and chains (and equivalent cycles and chains) present in the molecular structure has been proven appropriate for classification of chemical databases, giving rise to a generation of different classification levels depending on the structural elements (cycles and chains) that are considered. In this paper we propose a screening model, compatible with the cycle graphs model, based on a hierarchy of levels of abstraction. The set of molecules that satisfies a screening model (or selection criterion) diminishes as we advance in the hierarchy of levels of the model, which allows filtering of records and, therefore, an increase in the efficiency of the screening process. In the following work of this series we describe and validate the screening tool developed. 相似文献
90.
Miguel A. Bañares Amador Angoso Juan L. Manzano Emilio Rodríguez 《Transition Metal Chemistry》1987,12(2):149-152
Summary Cobalt(II) chlorocomplexes with empirical formulae (bnH2)2CoCl6·2H2O (1) and (bnH2)2CoCl6 (2), where bnH
2
2+
represents the diprotonated species of putrescine (1,4-butanediamine), were prepared.The visible spectra in the solid state and measurement of the magnetic moments permit the assignation of an octahedral geometry for cobalt in (1) and a tetrahedral geometry for (2). 相似文献