Synthesis and Application of Poly(diallyldimethylammonium tribromide)as a Novel Polymeric Brominating Agent

In this study, the synthesis and applications of a new supported tribromide reagent based on poly(diallyldimethylammonium chloride) is reported. This supported tribromide is used in α‐bromoacetalization of ketones, bromination of alkenes and regioselective bromination of activated aromatic compounds. This method is mild and no Br₂ and HBr were used. Other advantages of this reagent are stability, high efficiency, simple filtera‐ bility and reusability.     

A novel approach to analyze photoinduced effects in a DR1 dye-doped hybrid nanocomposite film

Photoinduced effects were analyzed through a novel approach in a guest-host DR1 dye-doped organic–inorganic nanocomposite at two cured and uncured cases. Moreover, the investigation was performed for the material over curing process. The results reflect that by increasing the heating time and completing the curing procedure, birefringence, dichroism, and the maximum probe transmittance will be enhanced. The best time of complete curing of the sample at the temperature 140 °C was also determined by measuring the saturated birefringence-probe intensity once every 40 min. In this approach, it was proved that the least time needed for complete curing of the sample was about 4 h. Last but not least, comparing rise and fall times in the birefringence-probe intensity of the cured sample (as a thermoset polymer) with that of a DR1 dye-doped poly (methyl methacrylate; PMMA; as a thermoplastic polymer of the second kind) showed that how the dye molecules can behave completely different in the two microscopically rigid and flexible structures.     

Parallel machines scheduling to minimize job tardiness and machine deteriorating cost with deteriorating jobs

This paper studies the parallel machines bi-criteria scheduling problem (PMBSP) in a deteriorating system. Sequencing and scheduling problems (SSP) have seldom considered the two phenomena concurrently. This paper discusses the parallel machines scheduling problem with the effects of machine and job deterioration. By the machine deterioration effect, we mean that each machine deteriorates at a different rate. This deterioration is considered in terms of cost which depends on the production rate, the machine’s operating characteristics and the kind of work done by each machine. Moreover, job processing times are increasing functions of their starting times and follow a simple linear deterioration. The objective functions are minimizing total tardiness and machine deteriorating cost. The problem of total tardiness on identical parallel machines is NP-hard, thus the problem with machine deteriorating cost as an additional term is also NP-hard. We propose the LP-metric method to show the importance of our proposed multi-objective problem. A metaheuristic algorithm is developed to locate optimal or near optimal solutions based on a Tabu search mechanism. Numerical examples are presented to show the efficiency of this model.     

Novel fused 1,2,3-triazolo-benzodiazepine derivatives as potent anticonvulsant agents: design,synthesis, in vivo,and in silico evaluations

Molecular Diversity - A novel series of 1,2,3-triazolo-benzodiazepine derivatives 6a–o has been synthesized and evaluated in vivo for their anticonvulsant activities using by...     

A solvent-free reaction between acetophenone oximes and epoxy styrenes: an efficient synthesis of 2,4,6-triarylpyridines under neutral conditions

An efficient synthesis of 2,4,6-triarylpyridines is described which involves heating a mixture of an acetophenone oxime and an epoxy styrene under neutral, solvent-free conditions. Kröhnke pyridine products are obtained in excellent yields.     

One-pot synthesis of oxoisoindoline-1,2,3-triazole hybrid by a Ugi–click reaction

1,2,3-Triazole-3-oxoisoindoline-1-carboxamide system was successfully synthesized by using a combination of Ugi and click reactions. This two-step, one-pot synthesis was started by the reaction of 2-formyl benzoic acid, propargyl amine, and cyclohexyl isocyanide in ethanol. The resultant Ugi adduct underwent a copper-catalyzed click reaction, producing the desired products in good yields.     

Recent Development of Polyolefin‐Based Microporous Separators for Li−Ion Batteries: A Review

Secondary Li?ion batteries have been paid attention to wide‐range applications of power source for the portable electronics, electric vehicle, and electric storage reservoir. Generally, lithium‐ion batteries are comprised of four components including anode, cathode, electrolyte and separator. Although separators do not take part in the electrochemical reactions in a lithium‐ion (Li?ion) battery, they conduct the critical functions of physically separating the positive and negative electrodes to prevent electrical short circuit while permitting the free flow of lithium ions through the liquid electrolyte that fill in their open porous structure. Hence, the separator is directly related to the safety and the power performance of the battery. Among a number of separators developed thus far, polyethylene (PE) and polypropylene (PP) porous membrane separators have been the most dominant ones for commercial Li?ion batteries over the decades because of their superior properties such as cost‐efficiency, good mechanical strength and pore structure, electrochemical stability, and thermal shutdown properties. However, there are main issues for vehicular storage, such as nonpolarity, low surface energy and poor thermal stability, although the polyolefin separators have proven dependable in portable applications. Hence, in this review, we decide to provide an overview of the types of polyolefin microporous separators utilized in Li?ion batteries and the methods employed to modify their surface in detail. The remarkable results demonstrate that extraordinary properties can be exhibited by mono‐ and multilayer polyolefin separators if they are modified using suitable methods and materials.     

Design and synthesis of 2,4-dioxochroman-pyridinium-phenylacetamide derivatives as new anti-Alzheimer agents: in vitro and in silico studies

2,4-Dioxochroman-pyridinium-phenylacetamide derivatives 7a–n were synthesized and evaluated for their in vitro cholinesterase (ChE) inhibitory activities against acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE). Obtained results demonstrated that, among the synthesized compounds, two compounds, 7j and 7k , were more potent than the standard drug donepezil against BuChE and did not show cytotoxicity and carcinogenicity. Furthermore, through molecular modeling and molecular dynamic studies. we showed that these compounds can be located deep in the gorge cavity of BuChE and that they interacted with catalytic residues, acyl, and cholin-binding pockets of this enzyme. Support information     

Amine-carbon disulfide promoted synthesis of novel benzo[e][1,3]thiazepin-5(1H)-one derivatives

In this paper, a simple method is introduced for the synthesis of novel 4-substituted-3-thioxo-3,4-dihydrobenzo[e][1,3]thiazepin-5(1H)-one derivatives. The synthesis is based on a two-step reaction of 2-methylbenzoic acid, an amine, and carbon disulfide. In the first step, 2-methylbenzoic acid reacts with sulfuric acid in ethanol, followed by the reaction with N-bromosuccinimide to produce ethyl 2-(bromomethyl)benzoate. Amine and carbon disulfide react in a separate flask in basic medium to give carbamodithioate salt. Carbamodithioate and ethyl 2-(bromomethyl)benzoate react together in dimethylformamide to produce the desired 4-substituted-3-thioxo-3,4-dihydrobenzo[e][1,3]thiazepin-5(1H)-one derivatives. The method is simple and fast and is applicable to a wide variety of substrates and gives the desired products in high isolated yields.     

Sulfonic acid-functionalized poly(4-styrenesulfonic acid) mesoporous graphene oxide hybrid for one-pot preparation of coumarin-based pyrido[2,3-d]pyrimidine-dione derivatives

Research on Chemical Intermediates - Sulfonic acid-functionalized poly(4-styrenesulfonic acid) mesoporous graphene oxide hybrid (PSSA-MGO) is prepared by polymerization of 4-styrenesulfonic acid on...