Poly[μ‐aqua‐μ4‐naphthalene‐1,8‐dicarboxylato‐zinc(II)]

In the title complex, [Zn(C₁₂H₆O₄)(H₂O)]_n, a Zn^II polymer based on naphthalene‐1,8‐dicarboxylate (1,8‐nap), the Zn^II atoms adopt an elongated octahedral coordination geometry. A zigzag chain is formed by μ₂‐aqua ligands and μ₂‐carboxylate groups of the 1,8‐nap ligands. Adjacent parallel chains are further linked by 1,8‐nap ligands, forming a twisted two‐dimensional layer structure along the (100) plane.     

Terephthalamide derivatives as mimetics of helical peptides: disruption of the Bcl-x(L)/Bak interaction

A series of Bcl-x(L)/Bak antagonists, based on a terephthalamide scaffold, was designed to mimic the alpha-helical region of the Bak peptide. These molecules showed favorable in vitro activities in disrupting the Bcl-x(L)/Bak BH3 domain complex (terephthalamides 9 and 26, K(i) = 0.78 +/- 0.07 and 1.85 +/- 0.32 microM, respectively). Extensive structure-affinity studies demonstrated a correlation between the ability of terephthalamide derivatives to disrupt Bcl-x(L)/Bak complex formation and the size of variable side chains on these molecules. Treatment of human HEK293 cells with the terephthalamide derivative 26 resulted in disruption of the Bcl-x(L)/Bax interaction in whole cells with an IC(50) of 35.0 microM. Computational docking simulations and NMR experiments suggested that the binding cleft for the BH3 domain of the Bak peptide on the surface of Bcl-x(L) is the target area for these synthetic inhibitors.     

原位沉析法制备磁性氧化铁羟基磷灰石/壳聚糖棒材

首先通过化学沉淀法制备磁性氧化铁羟基磷灰石(Fe3O4/HA),然后以壳聚糖(CS)为基体,利用原位沉析法将Fe3O4/HA与CS复合,制得磁性Fe3O4/HA/CS复合材料.经XRD、粒径分布和PPMS测试,结果表明了Fe3O4/HA复合物的生成.系统研究了磁性Fe3O4/HA/CS棒材力学性能的影响因素,最终确定Fe3O4与HA质量比为3∶17,磁性Fe3O4/HA与CS质量比为9∶91时,棒材的力学性能最优,弯曲强度可达到87.0 MPa,弯曲模量1.57 GPa.     

水中溶解氧的微量滴定

将微量滴定技术应用于常规的碘量法测定水中溶解氧。在实验中采用了WD-CO3型微量滴定装置，并使用自行设计制成的高精度微量移液管（移液的体积可准确至0．001mL），作为转移标准溶液及试样溶液的工具。对微量滴定及微量移液与常量滴定和常量移液作了对比试验，结果表明两者的分析结果完全吻合，微量滴定（其中包括微量移液）所得结果的精密度也在定量分析允许范围之内。由此，微量滴定技术应用于水中溶解氧的日常分析的可行性得到了验证。     

钢筋混凝土旧工业厂房结构加固方案优选

当前人们选择旧工业厂房结构加固方案效率低下,且所考虑的因素较为片面,为了全面、高效地解决这一问题,通过综合考虑安全性、经济性、时间性、可行性和适用性等因素,以加固效果显著的工程案例为标准,以全面的18个参数为评价指标,构建了一种基于蛛网面积相似和形状相似的结构加固方案优选模型。该模型中首先运用熵权法确定18个指标权重,并将参数值归一化处理,随后运用Python计算蛛网结构相似度,检索出与目标范例最为相似的源范例。最后以结构加固效果显著的工程为例,验证了该模型能有效减少主观误差,具有较强的实用性,并以此模型优选出了某轧钢厂房结构加固方案。     

Phase Selectively Soluble Dendritic Derivative of 4-(Dimethylamino)- pyridine: An Easily Recyclable Catalyst for Baylis-Hillman Reactions

Among the reactions in which C-C bonds are formed, the Baylis-Hillman coupling of aldehydes with α, β-unsaturated carbonylic compounds is currently attracting much interest due to the atom economy, the mild conditions and the generation of functional groups1,2. Furthermore, compared to the Heck, Suzuki and other palladium catalyzed C-C bond forming reaction3, the Baylis-Hillman reaction can be promoted by using organic bases in the complete absence of any metal4. However, almost all the …     

Controllable self-assembly of parallel gold nanorod clusters by DNA origami

We demonstrate the self-assembly of three types of parallel gold nanorod clusters using a rod-like DNA origami as the template.     

一种新型双亚胺吡啶铁系催化剂的乙烯低聚研究

线性α 烯烃广泛地应用于洗涤剂、增塑剂、润滑油等精细化学品的合成以及作为共单体制备线性低密度聚乙烯 (ＬＬＤＰＥ) .目前工业上主要是应用ＳＨＯＰ法[1] 、Ｃｈｅｖｒｏｎ工艺和Ａｍｏｃｏ工艺[2 ] 通过乙烯低聚制备 .近些年发展起来的新型高活性后过渡金属乙烯低聚催化剂能够高选择性地制备线性α 烯烃[3 ,4] .Ｂｒｏｏｋｈａｒｔ等[4] 的研究表明 ,对于双亚胺吡啶铁系乙烯聚合催化剂而言 ,配体上苯基的邻位取代基位阻减小可以实现乙烯低聚 ,并具有高活性、高选择性以及理想的低聚产物分布 .本文的工作是从配体的空间位阻效应对催化剂…     

Synthesis of Highly Porous Organic/Inorganic Hybrids by Ambient Pressure Sol-Gel Processing

This paper reports the synthesis of highly porous organic/inorganic hybrids by a two-step acid-base catalyzed sol-gel process and ambient pressure drying. In the method organic and inorganic precursors are copolymerized so as to incorporate organic ligands into the solid network. The two-step acid-base catalyzed process was used to prevent phase segregation during the hydrolysis and co-condensation of organic and inorganic precursors. The organic ligands incorporated into the solid gel network modify the surface chemistry. Thus, the wetting angle is significantly increased so that the collapse of the gel network is greatly reduced upon the removal of pore fluid during drying. Organic/inorganic hybrids with BET surface areas above 1250 m2/g, porosities above 75% and pore sizes of 8 nm have been synthesized.     

Anti-solvent assisted treatment for improved morphology and efficiency of lead acetate derived perovskite solar cells

An efficient solution-processable route employing Pb(Ac)₂ as lead source and anti-solvent treatment to achieve fully covered and homogenous perovskite films is reported.