Synthesis and Crystal Structure of 1,2,4,6-Tetraphenyl-2-hydroxy-8-azabicycle[3,2,1]octane

1 INTRODUCTIONAtrope alkaloids, which exist in eggplant plants, such as atrope and scopolamine, are used as a series of important drugs in medical science [1,2]. The typical character of atrope alkaloid is that these compounds contain the main skeleton of 8-azabicycle[3,2,1]octane , which results in the very complicated synthetic routine[3]. During our research for the reaction of 1,3,5,7-tetraphenyl-4- nitro-1,7-heptadione with low-valent titanium reagent, we easily synthesized the title …     

格拉司琼与磷钨杂多酸相互作用的共振光散射及分析应用

在pH 2.2 BR缓冲介质中, 磷钨杂多酸(PTA)与格拉司琼(GSN)相互作用形成离子缔合物, 不仅引起吸收光谱的变化, 还导致共振散射光谱(RLS)的显著增强并产生新的RLS光谱, 最大RLS峰位于333 nm附近, 其RLS增强程度与格拉司琼浓度成线性关系, 检出限和线性范围分别为12 ng/mL和0.04～3.0 μg/mL。文中研究了反应产物的吸收和RLS光谱特征, 优化反应条件的影响, 据此发展了以磷钨杂多酸为光谱探针的灵敏、简便、快速测定格拉司琼的新方法。将方法用于血清中格拉司琼含量的快速定, 结果满意。讨论了离子缔合反应和RLS增强机理。     

蜂产品中蛋白质测定方法的改进

蜂产品中蛋白质的测定主要采用凯氏定氮法,其测定结果稳定可靠,被广泛采用.但其操作较繁杂,消化时间长,需蒸馏滴定,费时费力.本法通过改进消化条件,即采用过氧化氢-浓硫酸混合液为消化液,消化过程中滴加硝酸-高氯酸混合酸,缩短了消化时间.样品中的蛋白质与硫酸和催化剂一同加热分解,生成的氨与硫酸反应生成硫酸铵,硫酸铵在碱性溶液中与次氯酸盐生成-氯胺,在亚硝基铁氰化钠催化作用下与水杨酸生成蓝色化合物,可在655 nm波长下比色定量.     

河蟹育苗池塘水质管理技术的初步研究

结合河蟹土池育苗实际，对育苗池塘易出水质问题的时期、主要原因及其表现展开讨论；并对常见水质问题引发的影响及其后果进行了详细剖析．据此，提出了彻底清塘消毒、适时施肥、合理投饲、充分利用增氧机械、适时适量加换新水等育苗池塘水质管理的实用技术，为有效管理水质提供参考．     

刀具问题的仿真及灵敏度分析

本文通过计算机模拟仿真 ,搜索到了 CMCM-99A题中换刀间隔与检查间隔的近似最优解及单位正品最小费用 ,并对 p1(好刀生产正品的概率 ) ,p2 (坏刀生产正品的概率 ) ,k,f,d进行了灵敏度分析 ,得出 u(换刀间隔 )是最重要的优化参数的结论     

Hyperpolarizabilities of Chelidamic Acid Complexes M_m(C_7H_3O_5N)_n (M=Cu, Ag): Theoretical Analysis

The frequency‐dependent hyperpolarizabilities of chelidamic acid complexes M_m(C₇H₃O₅N)_n (M?Cu, Ag) were investigated under the time dependent density functional theory (TDDFT) combined with the sum‐over‐states method (SOS). The relationship between molecular orbitals and nonlinear optical (NLO) properties has been explored. The results show that the charge transitions of π‐π* and 3d_M‐π* are very important to the second‐order polarizabilities, and the largest component of dynamic β is 3.84×10^?25 cm⁵·esu^?1 at 0.74 eV for Ag₂Cu₂(C₇H₃O₅N)₄. The charge transition between π‐π* is also highly crucial to the third‐order polarizabilities, and the largest component of dynamic γ is ?4.46×10^?29 esu at 0.50 eV for Ag₂Cu₂(C₇H₃O₅N)₄. The central Cu ion, as electron bridge, extends the range of delocalization and leads to an interesting phenomenon of spiroconjugation.     

On the shepherding of Uranian epsilon ring

To explain the long-term existence of Uranian narrow rings, we study the dynamical evolution of Uranian epsilon ring under the influence of its two shepherding satellites: Cordelia and Ophelia. The model of planar-elliptic restricted three-body problem is employed, in which the three bodies are Uranus, a satellite and a test particle. Dissipations due to interparticle collisions are also taken into consideration. A mapping system has been obtained based on the differential equation system. Numerical results show that only those particles originally lying in the libration region of the resonance can be shepherded. The size of the libration region depends mainly on the orbital eccentricity and mass of the shepherd satellite. For the outer shepherd Ophelia with larger orbital eccentricity, if its mass is a third of the nominal mass 2.5 × 10¹⁹ g, most of the orbits are regular and the outer edge of the ring can be shepherded, but more fuzzy than the inner edge. Thus we infer that Ophelia has a smaller mass.     

明胶接枝磺化缩聚物油井水泥分散剂的合成与性能

以动物明胶为原料,通过与甲醛、丙酮和焦亚硫酸钠发生磺化接枝反应,合成了一种新型的明胶接枝磺化缩聚物油井水泥分散剂.利用红外光谱分析测试技术证明了在明胶分子侧链上引入了磺化缩聚物.测试结果表明,当合成分散剂加入质量分数为1%时,水泥浆的流性指数、稠度系数和稠化时间比值(与未加水泥浆)分别为1.124、O.014和1.02,抗压强度比值均大于1.0,在18%NaCl、37%NaCl和2%CaCl,盐水水泥浆的流性指数分别为1.021、1.087和0.914、稠度系数分别为0.035、0.025和0.063.结果证明.明胶接枝磺化缩聚物的分散性能优异、耐盐性强并且无缓凝副作用,性能与常用的磺化醛酮缩聚物分散剂接近.是一种新型的预期可生物降解的油井水泥分散剂.     

Two Novel Poly-Oxygen Bipyridine Alkaloids from Speranskia tuberculata

In a previous paper' we reported two optically active pyridine-2, 6 (l H. 3H)-dionealkatoids speranskalines A and B from SPeranskia luberculala (Bge.) (Euphorbiaceae)We report here the isolation and structural elucidation of two novel poly-oxygenbipyridine alkaloids named speranculatines A (l) and B (2) from this plant.The acetone (or methanol) extract of the air-dried whole plants of .q. IllhelT.lllaluwas subjected to column chromatography on St gel to afford a fraction. whichdemonstrate…     

Practical synthesis of new functionalized tetraphenylenes

The practical synthesis procedure of substituted tetraphenylene derivatives involving the synthesis of a precursor for 4, 7-dunethoxyisobenzofuran and Diets-Alder addition of 4, 7-dimethoxyisobenzofuran generated in situ to 5, 6, 11,12-te-tradehydrodibenzo[a,e]cyclooctene, followed by a low valent titanium mediated deoxygenation to give 1,4, 11, 14-tetra-methoxy-dibenzo[b, n] tetraphenylene, which can be further demethyiated to the corresponding phenolic compound, which was acetylated to afford 1,4,11,14-tetraacetoxy-dibenzo-[ b, n] tetraphenylene.