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101.
本文采用八步分离提取法,成功地从2,800,000个家蚕(Bombyx mori)雄蛾头部提取和初步纯化了脑激素——即促前胸腺激素(PTTH),称为“粗制PTTH”.脑激素粗提物约7微克经蓖麻蚕无脑蛹的测试表明具有生物活性.又由100,000个家蚕蛾头分离提取的粗制PTTH,再经过四步凝胶柱层析进一步纯化,结果获得3.4毫克更纯的脑激素(“高纯度PTTH”).用7毫微克高纯度PTTH,即可使去脑蓖麻蚕施发育为成虫. 相似文献
102.
The advanced medical technology has lengthened the life expectancy of human beings.This makes some previously ignored diseases prominent, such as Alzheimer disease(AD). The low level of acetylcholine (ACh) in brain is considered to be one of mainreasons for suffering such memory loss disease. Thereby, how to elevate ACh level inbrain and enhance the cognition has become a main issue l'2. One of the approaches is toinvestigate acetylcholinesterase (AChE) inhibitors, which can prevent the hy… 相似文献
103.
Yu ZHAO * Yuan Ling KU Shoei Sheng LEE* Laboratory of Phytochemistry Kunming Institute of Botany Chinese Academy of Sciences Kunming School of Pharmacy College of Medicine National Taiwan University Taipei 《中国化学快报》2000,11(12)
One of the strategies of bettering Alzheimer's Disease is focused on cholinergic compound based on the cholinergic hypothesis1. An important approach to cholinergic augmentation is administration of cholinesterase inhibitors such as Huperzine A2. Territrem B is a potent AChE inhibitor (IC50 47 nM, H. Zea AchE)3, and its inhibitory mechanism is totally different with the known AChE inhibitors4. In the last report we have described three routes of synthesizing Territrem B analogues, whic… 相似文献
104.
Core shell magnetite nanoparticle (CSMN) was successfully synthesized with diameter around 125 nm according to the determination
with scanning electronic microscopy. SBA-15 with diameter around 31 nm was synthesized in our previous work as another supporter
for immobilized degradation enzymes. The aim of this study was to investigate the influence of silica-derived nano-supporters
on cellobiase after immobilization. With covalent method, glutaraldehyde was introduced to immobilize cellobiase. The immobilized
enzyme efficiency, specific activity, and its characterization, including optimum pH, pH stability, optimum temperature for
enzyme reaction, and enzyme thermal stability were investigated. Results show that the method of enzyme immobilization on
both nano-supporters could improve cellobiase stability under low pH and high temperature conditions compared with the free
enzyme. In the aspect of immobilization efficiency, SBA had higher amount of bounded protein than that of CSMN, but had lower
specific enzyme activity than CSMN, assumably due to the change in silica surface properties caused by process of supporter
synthesis. 相似文献
105.
Hydrodynamic properties of squirmer swimming in power-law fluid near a wall considering the interaction between squirmer and wall are numerically studied with an immersed boundary-lattice Boltzmann method. The power-law index, Reynolds number, initial orientation angle of squirmer, and initial distance of squirmer from the wall are all taken into account to investigate the swimming characteristics for pusher (β?<?0), neutral squirmer (β?=?0), and puller (β?>?0) (three kinds of swimmer types) near the no-slip boundary. Four new kinds of swimming modes are found. Results show that, for the pushers and pullers, the wall displays an increasing attraction with increasing power-law index n, which differs from the neutral squirmer who always departs from the wall after the first collision with the wall. Both the initial orientation angle and initial distance from the wall only affect the moving situations rather than the moving modes of the squirmers. However, the squirmers depart from the wall as the Reynolds number increases and chaotic orbits appear for some squirmers at Re?=?5. Several typical flow fields are analyzed and the power consumption and torque for different kinds of flows are also studied. It is found that, as the absolute value of β increases, the power consumption generally increases in shear-thinning (n?=?0.4), Newtonian (n?=?1), and shear-thickening (n?=?1.6) fluids. Moreover, the pushers (β?<?0) and the pullers (β?>?0) expend almost the same power if the absolute value of β remains the same. In addition, the power consumption of the squirmers is highly dependent on the power-law index n. 相似文献
106.
In this paper, we generalized the results of [23, 26], and get the results of the condition number of the W-weighted Drazin-inverse solution of linear systemWAWx =b, whereA is anm x n rank-deficient matrix and the index ofAW isk 1, the index ofWA isk 2,b is a real vector of sizen in the range of (WA) k2 ,x is a real vector of sizem in the range of (AW) k1 . Let α and β be two positive real numbers, when we consider the weighted Frobenius norm $\left\| {\left[ {\alpha W AW,\beta b} \right]} \right\|_{Q,\tilde P}^{(F)} $ on the data we get the formula of condition number of the W-weighted Drazin-inverse solution of linear system. For the normwise condition number, the sensitivity of the relative condition number itself is studied, and the componentwise perturbation is also investigated. 相似文献
107.
本文提出一个方法,来推求在(3)式中所定义的、在全空间中的格林张量函数。它有时亦称为对应微分方程的基本解。这个方法是以富氏变换为基础。由于问题的复杂性,我们不得不作某些近似。首先,把各向异性介质分为两类,一类是磁迴旋介质,另一类是电迴旋介质。对于磁迴旋介质,如铁氧体,取μ为张量而ε为标量。而对电迴旋介质,如等离子体,取ε为张量而μ为标量。其次,由于矩阵μp非常小(在(15)式中定义),我们可以把解展为μp的冪级数,并计算出一级近似。具体结果在式(23)、(25)、(28)、(32)和(33)中表示。最后对Г函数的物理意义和它的渐近展开式的有效范围作了讨论。 相似文献
108.
Motion of fibres in sheared fibre suspensions is simulated numerically by using the lattice Boltzmann method. The orientational distributions of the fibres are presented for different Reynolds numbers, Stokes numbers, shear rate and fibre aspect ratio. Some computational results are compared with the experimental data of pipe flow, and the qualitative agreement is achieved. The results show that the orientational distributions are greatly affected by the Reynolds numbers, while relatively insensitive to the fibre aspect ratio. The Stokes number and shear rate have obvious influence on the orientation distribution. 相似文献
109.
An erbium-doped fiber laser that emits a series of spectrally scanned pulses is used to monitor an array of fiber Bragg grating (FBG) sensors. The cavity for this Fabry-Perot laser is formed by two spectrally selective reflectors: a rotating mirror-grating combination for scanning the reflectance peak wavelength and a fiber Fabry-Perot interferometer (FFPI) with a periodic reflectance spectrum. During a scan of the rotating mirror, the laser produces a set of Q-switched pulses over the 1522-1568-nm spectral range at each of the FFPI reflectance peak wavelengths. This laser is used to simultaneously demonstrate wavelength-division multiplexing of FBGs with reflectance peaks in different spectral regimes and time-division multiplexing of FBGs with overlapping spectra. The spectral location of the FBG peaks was determined to an accuracy of 1.4 pm. 相似文献
110.
Ping Gao Dr. M. Anji Reddy Dr. Xiaoke Mu Dr. Thomas Diemant Le Zhang Dr. Zhirong Zhao‐Karger Dr. Venkata Sai Kiran Chakravadhanula Dr. Oliver Clemens Prof. Dr. R. Jürgen Behm Prof. Dr. Maximilian Fichtner 《Angewandte Chemie (International ed. in English)》2016,55(13):4285-4290
A novel room temperature rechargeable battery with VOCl cathode, lithium anode, and chloride ion transporting liquid electrolyte is described. The cell is based on the reversible transfer of chloride ions between the two electrodes. The VOCl cathode delivered an initial discharge capacity of 189 mAh g?1. A reversible capacity of 113 mAh g?1 was retained even after 100 cycles when cycled at a high current density of 522 mA g?1. Such high cycling stability was achieved in chloride ion batteries for the first time, demonstrating the practicality of the system beyond a proof of concept model. The electrochemical reaction mechanism of the VOCl electrode in the chloride ion cell was investigated in detail by ex situ X‐ray diffraction (XRD), infrared spectroscopy (FTIR), transmission electron microscopy (TEM), and X‐ray photoelectron spectroscopy (XPS). The results confirm reversible deintercalation–intercalation of chloride ions in the VOCl electrode. 相似文献