Formation of organorhodium complexes via C-H bond activation of 1,3-di(phenylazo)benzene

Reaction of a potential NCN-pincer ligand, viz. 1,3-di(phenylazo)benzene (L), with [Rh(PPh(3))(3)Cl] affords, via a C-H bond activation, an interesting dinuclear Rh(II) complex (1), and with RhCl(3)·3H(2)O affords a mononuclear Rh(III) complex (2) containing a catalytically useful Rh-OH(2) fragment.     

Synthesis of Thioglycosides in Room Temperature Ionic Liquid

An eco-friendly reaction for the preparation of thioglycosides has been developed using an ionic liquid as the solvent. Thioglycosides were obtained in excellent yields on treatment of per-O-acetylated sugar derivatives with thiols in the presence of boron trifluoride diethyl etherate in [Bmim][BF₄] as solvent at 20°C. Supplemental materials are available for this article. Go to the publisher's online edition of Journal of Carbohydrate Chemistry to view the free supplemental file.     

“Stainomics”: Identification of mitotracker labeled proteins in mammalian cells

Organelle‐specific cell‐permeable fluorescent dyes are invaluable tools in cell biology as they reveal intracellular dynamics in living cells. Mitrotracker is a family of dyes that strongly label the mitochondrion, a key organelle associated with many crucial cellular functions. Despite the popularity of these dyes, little is known about the molecular mechanism behind their staining specificity. Here, we aimed to identify the protein targets of one member of this dye family, mitotracker red (MTR), by 2DE and MS. MTR bound to cellular proteins covalently, and its fluorescence persisted even after cell lysis, protein solubilization, denaturation, and electrophoresis. This enabled us to display MTR‐labeled proteins by 2DE. The MTR‐specific fluorescent signals on the gel revealed the spots that contained MTR‐conjugated proteins. These spots were analyzed by MS, resulting into the identification of ten proteins. We discovered that one major target is the mitochondrial protein HSP60 and that MTR staining could induce production of HSP60, predisposing cells to heat shock‐like responses. The identification of the molecular targets of biological dyes, or “stainomics,” can help correlate their intracellular staining properties with biochemical affinities. We believe this approach can be applied to a wide range of fluorescent probes.     

THE 31P NMR SPECTRA OF ISOMERIC DIAMINOHEXA-CHLOROCYCLOTETRAPHOSPHAZATETRAENES; EXAMPLES OF A2B2 AND AA'BB' SPIN SYSTEMS

Abstract

The ³¹P nmr spectra of 2,4- and 2,6-diamino-derivatives of octachlorocyclotetraphosphazatetraene, N₄P₄Cl₆(NR¹R²)₂ (R¹ = H, R² = Bu^t; R¹ = H, R² = CH₂Ph; R¹ = Me, R² = Ph), have been measured. The 2,4- and 2,6-isomers were analysed as AA'BB' and A₂B₂ spin systems respectively. In the 2,4-isomers the spin-spin couplings ²J(PNP) and ⁴J(PNPNP) were of opposite sign.     

An Error Analysis of Discontinuous Finite Element Methods for the Optimal Control Problems Governed by Stokes Equation

In this article, an abstract framework for the error analysis of discontinuous finite element method is developed for the distributed and Neumann boundary control problems governed by the stationary Stokes equation with control constraints. A priori error estimates of optimal order are derived for velocity and pressure in the energy norm and the L²-norm, respectively. Moreover, a reliable and efficient a posteriori error estimator is derived. The results are applicable to a variety of problems just under the minimal regularity possessed by the well-posedness of the problem. In particular, we consider the abstract results with suitable stable pairs of velocity and pressure spaces like as the lowest-order Crouzeix–Raviart finite element and piecewise constant spaces, piecewise linear and constant finite element spaces. The theoretical results are illustrated by the numerical experiments.     

Electronic energy levels of weakly coupled nanostructures: C60-metal interfaces

A new approach based on density functional theory and the Anderson impurity model is developed to calculate charging energies and quasiparticle energy gaps of molecular systems weakly coupled to an environment. The approach is applied to C60 adsorbed on Au(111) and Ag(100) surfaces, resulting in electronic structures that are in excellent agreement with recent experiments. Image-charge screening effects on molecular orbital energies are found to be of similar magnitude for the two surfaces, but charge-transfer screening and spin fluctuations also affect the Ag case due to a partially occupied C60 orbital.     

Factorized Duality,Stationary Product Measures and Generating Functions

We find all self-duality functions of the form

$$\begin{aligned} D(\xi , \eta )= \prod _{x} d(\xi _x, \eta _x) \end{aligned}$$

for a class of interacting particle systems. We call these duality functions of simple factorized form. The functions we recover are self-duality functions for interacting particle systems such as zero-range processes, symmetric inclusion and exclusion processes, as well as duality and self-duality functions for their continuous counterparts. The approach is based on, firstly, a general relation between factorized duality functions and stationary product measures and, secondly, an intertwining relation provided by generating functions. For the interacting particle systems, these self-duality and duality functions turn out to be generalizations of those previously obtained in Giardinà et al. (J Stat Phys 135:25–55, 2009) and, more recently, in Franceschini and Giardinà (Preprint, arXiv:1701.09115, 2016) . Thus, we discover that only these two families of dualities cover all possible cases. Moreover, the same method discloses all simple factorized self-duality functions for interacting diffusion systems such as the Brownian energy process, where both the process and its dual are in continuous variables.