Diastereoisomeric Separation of (R,S)-l,l'-Binaphthalene-2,2'-Diol-Mono-[(-)-Menthyl] Carbonate by RP-HPLC

(R)-l,l'-binaphthalene-2,2'-diol-mono-[(-)-menthyl] carbonate (1) and (S)-l,l'-binaphthalene-2,2'-diol-mono-[(-)-menthyl] carbonate (2) are two new compounds synthesized from racemic binaphthol by diastereoselective crystalization after derivatization with (-)-menthyl chloroformate. Reduction of these monoesters would afford pure enantiomers of binaphthol, which are important C₂-symmetrical compouds for asymmetric catalysis and the starting material for many other important chiral binaphthyl compounds.     

毛细管电泳环糊精添加剂立体选择性差异的研究

对在毛细管区带电泳环糊精子性拆分体系中手性药物妥布特罗的分离机理进行了探讨。分别测定了α、β、γ－环糊精和二甲基,三甲基,羟丙基－β－环糊精与药物对缺体形成包结配合物的稳定常数以及手性拆分过程中的热力学函数的变化,并对数据进行了分析。     

聚硅氧烷侧链甲基化β-环糊精键合交联手性毛细管柱分离对映体

合成了聚硅氧烷侧链的甲基化β-环糊精衍生物手性固定相,成功地进行了固载化,固载化程度高于90%。经测试,柱性能稳定,可在200℃下长期使用。暴露于空气中存放两年,柱效及选择性未见明显改变。对卤代烃及一些醇对映体的直接分离表现出良好的立体选择性,并应用于毛细管电色谱拆分手性化合物。     

锌卟啉衍生物的自组装研究

合成了一种新型的带有腺嘌呤取代基的锌卟啉并对其进行了表征。结果表明,腺嘌呤取代基与中心金属锌的轴向配位驱动了自组装。紫外可见和荧光光谱实验结果证明了由自组装而产生的卟啉低聚物的存在。     

手性添加剂磺丁基—β—环湖精的合成及毛细管电泳手性分离

以磺丁内酯为衍生试剂合成了两种不同取代度的磺丁基－β－环湖精,并对合成产物进行了表征,以这两种负电性的磺丁基－β－环湖精衍生物作为毛细这电泳手性添加剂,考察了它们对酸、碱性手性药物的手性拆分性能,以及不同取代度对手性拆分的影响。     

Novel and Efficient Resolution of 1,1'-Bi-2-naphthol and Synthesis of Optically Pure Unsymmetrically Substituted Binaphthyls

Both enantiomers of 1, 1'-Bi-2-naphthol (BINOL) 1 are important chiral ligands and auxiliaries for a number of asymmetric transformations such as aldol condensations, alkylations, Diels-Alder reactions, Michael additions, epoxidations, etc. Optically pure 1 and their derivatives have also been used extensively in chiral recognition, chiral separation and construction of functionalised materials^[1]. As a result the development of efficient and economic methods for the preparation of optically pure 1 has attracted much attention in recent years^[2] and novel methods for the resolution of racemic 1 (Rac-1) continue to be developed.     

电子俘获材料在光记录中的应用

研究了自行研制的CaS(Eu,Sm)电子俘获材料的光学性质;利用～200μm厚的CaS(Eu,Sm)高聚物膜作为记录底片,进行了实物图象的拍摄实验。这种记录材料具有很多有吸引力的优点:不需要用化学溶液进行定影显影,可以实时读出,可快速擦除,能反复使用,具有大的线性范围等。实验表明,电子俘获材料是一种很有前途的光记录材料。     

The Characteristic Equation of q-Deformed Bosonic Oscillator

The main goal of this paper is to deduce the characteristic equation of [N]. From the fundamental relation of q-deformed bosonic oscillator, we deduce a strict algebraic equation. After introducing a moderate boundary condition, we obtain the characteristic equation of number operator [N].Using this equation, we extract all the eigenvalues of operator [N] and write out the corresponding eigenstates. Then we obtain the completeness of the Hilbert space.     

甲烷利用菌催化烯烃环氧化的底物选择性, 细胞失活原因及产物对映体组成

研究了甲烷利用菌Methylomonas sp. GYJ3, Methylomonas sp. S, Methylomonas sp. Z201,Methylococcus capsulatus IMV3021, Methylosinus trichosporium IMV3011休止细胞催化烯烃环氧化的底物选择性, 细胞失活原因以及产物对映体组成。发生不同菌株和底物的环氧化活性不同。甲烷利用菌只能催化短链烯烃环氧化, 环烯烃和芳香烯烃无反应。对烯丙基型底物而言, 取代基大小和极性影响环氧化活性。丙烯环氧化活性最高, 烯丙醇不能环氧化。细胞失活的主要原因是环氧化产物的细胞毒性和反应体系中辅酶NADH损耗。手性气相色谱揭示甲烷利用菌催化烯烃环氧化形成外消旋产物。     

A REGULARIZATION SCHEME FOR OBTAINING BARDEEN ANOMALY

A new regularization operator, (e^{-Ø_L(X)Ø_R(X)/M2}+e^{-Ø_R(X)Ø_L(X)/M2})|_M→∞’ is proposed to calculate the variation of the fermion path-in-tegral measure under a chiral transformation, and the normal anomaly, i.e.Bardeen anomaly, is obtained .in this paper. Moreover, the non-Abelian anomaly of the cosec pure gauge fields is calcula-ted by means of this regularization operator.The corresponding results in Minkowski space can readily be obtained in the principal value integral.