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111.
Soyoung Yun Eunok Lee Young-Kwon Park Soon-Yong Jeong Jeongsik Han Byunghun Jeong Jong-Ki Jeon 《Research on Chemical Intermediates》2011,37(9):1215-1223
In this study, in order to develop catalysts for the selective isomerization of higher paraffin, the hydroisomerization reaction of n-dodecane was performed as a model reaction. Pt/ZSM-48, Pt/HZSM-5, Pt/HY, and Pt/SAPO-11 were examined for the selective hydroisomerization of n-dodecane. The catalysts were characterized via X-ray powder diffraction, N2 adsorption, and the temperature-programmed desorption of ammonia. Among the catalysts studied, the Pt/HZSM-48 catalyst exhibited the best isomerization selectivity in the hydroisomerization reaction of n-dodecane, which is attributed to the moderate acid sites and medium-sized pores present in the HZSM-48. The highest iso-dodecane yield was obtained at a reaction temperature of 280 °C in the Pt/HZSM-48 catalyst. The optimal selectivity of the n-dodecane hydroisomerization over the Pt/SAPO-11 catalyst was obtained at approximately 300 °C, which was slightly higher than that of the Pt/HZSM-48 catalyst. 相似文献
112.
We synthesized five novel uridine-based cationic nucleolipids, introducing basic amino acid residues at the 5' position of uridine, through 1,3-dipolar cycloaddition, and hydrophobic alkyl moieties at the 2' and 3' positions, through carbamate linkages. Their lipoplexes delivered siRNAs efficiently to cells, in vitro, without any severe toxicity. 相似文献
113.
A novel supermolecular tetrameric vanadate-selective colorimetric and "off-on" sensor with pyrene ligand 总被引:1,自引:0,他引:1
Tris(2-((ethylimino)methyl)pyren-1-ol)amine (1) was synthesized and introduced as the first tetrameric vanadate fluorescence sensor, the entire binding of which was successfully accomplished in two steps with distinct colorimetric changes and "off-on" fluorescent enhancement. 相似文献
114.
A simple and sensitive approach for the detection of marker protein, phosphinothricin acetyltransferase, from genetically
modified crops was developed based on the colorimetric transition of polydiacetylene (PDA) vesicles in combination with silica
microbeads. PDAs have attracted a great deal of interests as a transducing material due to their special features that allow
colorimetric response to sensory signals, as well as their inherent simplicity. However, most PDA-based biosensors require
additional analytical equipment such as a fluorescence microscope or UV–Vis spectrometer. In this study, we report a new approach
to increase the degree of color transition by coupling antibody-conjugated PDA vesicles with silica microbeads in an effort
to monitor the results with the unaided eye or simple RGB analysis. By immobilizing PDA vesicles on silica microbeads, we
were able to overcome the disadvantages of colloidal PDA-based sensors and increase the degree of colorimetric changes in
response to target molecules to a concentration as low as 20 nM. The additional stresses were given to PDA vesicles by antigen–antibody
bridging of PDA vesicles coupled with microbeads, resulting in enhanced blue–red color transition. All the results showed
that PDA vesicles in conjunction with silica microbeads will be a promising transducing material for the detection of target
proteins in diagnostic and biosensing applications. 相似文献
115.
Jong Sam Jeon 《Linear algebra and its applications》2011,435(5):1147-1156
Let A be an n×n irreducible ray or sign pattern matrix. If A is a sign pattern, it is shown that either A is powerful or else Ak has an ambiguous entry for some , and further, sign patterns based on the Wielandt graph show that this bound is the best possible. If A is a ray pattern, partial results for the same bound are given. 相似文献
116.
Kim K Choi SH Jeon J Lee H Huh JO Yoo J Kim JT Lee CH Lee YS Churchill DG 《Inorganic chemistry》2011,50(12):5351-5360
One 8-phenyl and two 8-mesityl-substituted "scorpionate"-like BODIPY-type species of the formula [3,4,4-tris(5-R-(2-thienyl))-8-(2,4,6-R'-phenyl)-4-bora-3a,4a-diaza-s-indacene (R = H, R' = H, 3a; R, = H, R' = Me, 2a; R, = Me, R' = Me, 2b)] have been synthesized and fully characterized. Importantly, differences in their solution (MeCN) optical Cu(2+) and Hg(2+) probing capacity via SSS-chelation were investigated. Compounds 2a-3a were prepared from the requisite 8-substituted BODIPY complexes. They were characterized first by complete (1)H, (11)B and (13)C NMR spectroscopic assignments (CD(3)Cl or CD(3)C(O)CD(3)); the molecular structures of 2a and 3a were determined by X-ray crystallography. Compounds 2a-3a were studied by UV-vis and fluorescence spectroscopy [Φ(F) = 0.27 ± 0.013 (2a); 0.024 ± 0.0016 (2b); 0.0034 ± 0.00047 (3a)]. Importantly, low [Cu(2+)] with 3a (<3.0 × 10(-5) M) gave rise to an increase of fluorescence intensity (off-on; 6.3-fold), whereas with 2a it decreased (on-off). When [Hg(2+)] (<3.0 × 10(-5) M) was added to 2b, the λ(em,max) value increased (off-on; 3.2-fold), and for 2a, it decreased (on-off). The association constant (K(a)) for Hg(2+)·2a was determined to be 3120 ± 307 M(-1). An approximate stoichiometric 1:1 binding determined by Job plot analysis is in line with successful DFT modeling of SSS-Cu(2+) binding for this system type. (1)H NMR spectroscopy also revealed tentative sets of product complex peaks. These simple differences caused by formal ligand Me-group incorporation are the first for any related fluorophores, to the best of our knowledge. 相似文献
117.
Choi JH Park JG Jeon HJ Kim MS Lee MR Lee MN Sonn S Kim JH Lee MH Choi MS Park YB Kwon OS Jeong TS Lee WS Shim HB Shin DH Oh GT 《Experimental & molecular medicine》2011,43(8):471-478
A variety of benzylidenethiazole analogs have been demonstrated to inhibit 5-lipoxygenase (5-LOX). Here we report the anti-atherogenic potential of 5-(4-hydroxy- 2,3,5-trimethylbenzylidene) thiazolidin-2,4-dione (HMB-TZD), a benzylidenethiazole analog, and its potential mechanism of action in LDL receptor-deficient (Ldlr-/-) mice. HMB-TZD Treatment reduced leukotriene B4 (LTB4) production significantly in RAW264.7 macrophages and SVEC4-10 endothelial cells. Macrophages or endothelial cells pre-incubated with HMB-TZD for 2 h and then stimulated with lipopolysaccharide or tumor necrosis factor-alpha (TNF-α) displayed reduced cytokine production. Also, HMB-TZD reduced cell migration and adhesion in accordance with decreased proinflammatory molecule production in vitro and ex vivo. HMB-TZD treatment of 8-week-old male Ldlr-/- mice resulted in significantly reduced atherosclerotic lesions without a change to plasma lipid profiles. Moreover, aortic expression of pro-atherogenic molecules involved in the recruitment of monocytes to the aortic wall, including TNF-α , MCP-1, and VCAM-1, was downregulated. HMB-TZD also reduced macrophage infiltration into atherosclerotic lesions. In conclusion, HMB-TZD ameliorates atherosclerotic lesion formation possibly by reducing the expression of proinflammatory molecules and monocyte/macrophage recruitment to the lesion. These results suggest that HMB-TZD, and benzylidenethiazole analogs in general, may have therapeutic potential as treatments for atherosclerosis. 相似文献
118.
Cho CH Kang H Kang TE Cho HH Yoon SC Jeon MK Kim BJ 《Chemical communications (Cambridge, England)》2011,47(12):3577-3579
A simple and efficient approach of controlling the side-chain density in the electron donating polymers has been demonstrated to tune their 3-D packing structure and HOMO level, which increases the hole mobility and V(oc) values, thus improving the solar cell performance. 相似文献
119.
Single particle tracking in systems showing anomalous diffusion: the role of weak ergodicity breaking 总被引:1,自引:0,他引:1
Anomalous diffusion has been widely observed by single particle tracking microscopy in complex systems such as biological cells. The resulting time series are usually evaluated in terms of time averages. Often anomalous diffusion is connected with non-ergodic behaviour. In such cases the time averages remain random variables and hence irreproducible. Here we present a detailed analysis of the time averaged mean squared displacement for systems governed by anomalous diffusion, considering both unconfined and restricted (corralled) motion. We discuss the behaviour of the time averaged mean squared displacement for two prominent stochastic processes, namely, continuous time random walks and fractional Brownian motion. We also study the distribution of the time averaged mean squared displacement around its ensemble mean, and show that this distribution preserves typical process characteristics even for short time series. Recently, velocity correlation functions were suggested to distinguish between these processes. We here present analytical expressions for the velocity correlation functions. The knowledge of the results presented here is expected to be relevant for the correct interpretation of single particle trajectory data in complex systems. 相似文献
120.
Wang M Nalla V Jeon S Mamidala V Ji W Tan LS Cooper T Chiang LY 《The journal of physical chemistry. C, Nanomaterials and interfaces》2011,115(38):18552-18559
We demonstrated ultrafast femtosecond nonlinear optical (NLO) absorption characteristics of bilayered fullerosome vesicle nanostructures derived from molecular self-assembly of amphiphilic oligo(ethylene glycolated) C(60)-(light-harvesting diphenylaminofluorene antenna). Fullerene conjugates were designed to enhance photoresponse in a femtosecond time scale by applying an isomerizable periconjugation linker between the C(60) cage and diphenylaminofluorene antenna subunit in an intramolecular contact distance of only < 3.0 ?. Morphology of C(60)(>DPAF-EG(12)C(1))-based fullerosome nanovesicles in H(2)O was characterized to consist of a bilayered shell with a sphere diameter of 20-70 nm and a chromophore shell-width of 9.0-10 nm, fitting well with a head-to-head packing configuration of the molecular length. At the estimated effective nanovesicle concentration as low as 5.5 × 10(-8) MV (molecular molar concentration of 5.0 × 10(-4) M) in H(2)O, two-photon absorption (2PA) phenomena were found to be the dominating photophysical events showing a large molar concentration-insensitive 2PA cross-section value equivalent to 8500 GM in a form of nanovesicles, on average. The observed NLO characteristics led to a sharp trend of efficient light-transmittance intensity reduction at the input laser intensity above 100 GW/cm(2). 相似文献