Femtosecond Spectroscopy and Nonlinear Optical Properties of aza-BODIPY Derivatives in Solution

The fast relaxation processes in the excited electronic states of functionalized aza-boron-dipyrromethene (aza-BODIPY) derivatives ( 1 – 4 ) were investigated in liquid media at room temperature, including the linear photophysical, photochemical, and nonlinear optical (NLO) properties. Optical gain was revealed for nonfluorescent derivatives 3 and 4 in the near infrared (NIR) spectral range under femtosecond excitation. The values of two-photon absorption (2PA) and excited-state absorption (ESA) cross-sections were obtained for 1–4 in dichloromethane using femtosecond Z-scans, and the role of bromine substituents in the molecular structures of 2 and 4 is discussed. The nature of the excited states involved in electronic transitions of these dyes was investigated using quantum-chemical TD-DFT calculations, and the obtained spectral parameters are in reasonable agreement with the experimental data. Significant 2PA (maxima cross-sections ∼2000 GM), and large ESA cross-sections ∼10⁻²⁰ m² of these new aza-BODIPY derivatives 1–4 along with their measured high photostability reveal their potential for photonic applications in general and optical limiting in particular.     

Interpolation Methods for Curve Construction

This paper surveys a wide selection of the interpolation algorithms that are in use in financial markets for construction of curves such as forward curves, basis curves, and most importantly, yield curves. In the case of yield curves the issue of bootstrapping is reviewed and how the interpolation algorithm should be intimately connected to the bootstrap itself is discussed. The criterion for inclusion in this survey is that the method has been implemented by a software vendor (or indeed an inhouse developer) as a viable option for yield curve interpolation. As will be seen, many of these methods suffer from problems: they posit unreasonable expections, or are not even necessarily arbitrage free. Moreover, many methods lead one to derive hedging strategies that are not intuitively reasonable. In the last sections, two new interpolation methods (the monotone convex method and the minimal method) are introduced, which it is believed overcome many of the problems highlighted with the other methods discussed in the earlier sections.     

Effects of free stream turbulence on the distribution of heat transfer around turbine blade sections

Local convective heat transfer coefficients to a number of modern gas turbine blade sections have been measured under a wide range of mainstream conditions, from notionally steady flows to highly perturbed turbulent flows. The paper discusses the results and, through a detailed analysis of the pertinent boundary layer flow parameters and their relation to the observed experimental results, tests criteria for the occurrence of transition from laminar to turbulent boundary layers, a factor which all the data from this work confirm as critical in predicting the quantitative effects of mainstream turbulence on heat transfer rates. Artificially induced mainstream turbulence, which is endemic in the flows in a real turbine, enhances significantly the heat transfer rates, especially to the leading edge regions and on the pressure surface, particularly when the acceleration is tending to suppress transition. The results presented here confirm existing criteria for laminarisation and the applicability of some of those available for predicting laminar-turbulent transition. The observations also demonstrate how surface geometry can influence the stability of the flows, and the uncertainties which remain in assessing the effect of Goertler vortices and their role in the convective heat transfer process.     

Purification or contamination? The effect of sorbents on ionic liquids

Commonly used for purification, alumina and silica are found to contaminate ionic liquids with particles; these particles cannot be removed easily and can have a non-negligible impact on the electrochemical, spectroscopic and physical properties of an ionic liquid, including its nucleation and crystallisation kinetics.     

Electrical behavior of droplet interface bilayer networks: experimental analysis and modeling

Aqueous droplets submerged in an oil-lipid mixture become enclosed by a lipid monolayer. The droplets can be connected to form robust networks of droplet interface bilayers (DIBs) with functions such as a biobattery and a light sensor. Such DIB networks might be used as model systems for the study of membrane-based biological phenomena. In this study, we develop and experimentally validate an electrical modeling approach for DIB networks by applying it to describe the current flow through a simple network containing protein pores and blocking molecules. We demonstrate the use of SPICE (Simulation Program with Integrated Circuit Emphasis) for simulating the electrical behavior of DIB networks. The modular and scalable nature of DIB networks should enable a straightforward extension of the analysis presented in this paper to large, complex networks.     

(Poly)phenols in Inflammatory Bowel Disease and Irritable Bowel Syndrome: A Review

(Poly)phenols (PPs) may have a therapeutic benefit in gastrointestinal (GI) disorders, such as irritable bowel syndrome (IBS) or inflammatory bowel disease (IBD). The aim of this review is to summarise the evidence-base in this regard. Observational evidence does not give a clear indication that PP intake has a preventative role for IBD or IBS, while interventional studies suggest these compounds may confer symptomatic and health-related quality of life improvements in known patients. There are inconsistent results for effects on markers of inflammation, but there are promising reports of endoscopic improvement. Work on the effects of PPs on intestinal permeability and oxidative stress is limited and therefore conclusions cannot be formed. Future work on the use of PPs in IBD and IBS will strengthen the understanding of clinical and mechanistic effects.     

Strong two-photon absorption at telecommunications wavelengths in nickel bis(dithiolene) complexes

The two-photon absorption spectrum of a nickel bis(dithiolene) complex with extended conjugation and pi-donor substitution is measured by using Z-scan and pump-probe techniques with femtosecond pulses over the spectral range from 1.20 to 1.58 microm, which includes much of the telecommunications range. The peak two-photon cross section of over 5000 GM (1 GM = 10(-50) cm4 s photon(-1) molecule(-1)) occurs at approximately 1.24 microm, with significant two-photon absorption (>440 GM) throughout the spectral range examined.     

Nucleobase recognition at alkaline pH and apparent pKa of single DNA bases immobilised within a biological nanopore

The four DNA bases are recognized in immobilized DNA strands at high alkaline pH by nanopore current recordings. Ionic currents through the biological nanopores are also employed to measure the apparent pK(a) values of single nucleobases within the immobilised DNA strands.