Simple method to identify the spatial location better than the pulse length with high strain accuracy

The second-order partial derivative of the Stokes signal with respect to frequency and position shows a maximum or minimum at the boundary between two different strained sections. This idea is used to locate the boundary of different stress regions. Knowing the boundaries, we then fit the Brillouin spectrum at the middle between them to get the strain value. This allows a location accuracy of between 5 and 10 cm, which is shorter than the pulse length of 20 cm used in the experiment. The lowest detectable Brillouin frequency difference between two strain sections is 1.2 MHz.     

Sur les puissances de l’idéal fondamental de l’anneau de Witt

We reformulate a recent result of Arason and Elman by giving a very simple presentation of the powers of the fundamental ideal of the Witt ring of a field of characteristic 2.

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Sur les puissances de lidéal fondamental de lanneau de Witt

Nous reformulons un résultat récent de Arason et Elman en donnant une présentation très simple des puissances de lidéal fondamental de lanneau de Witt dun corps de caractéristique 2.

     

Power-law spatial correlations in arrays of locally coupled lasers

We investigate correlations of the intensity fluctuations of two-dimensional arrays of nonidentical, locally coupled lasers, numerically and experimentally. We find evidence of a power-law dependence of spatial correlations as a function of laser pair distance (or coupling strength) near the phase-locking threshold.     

Easy and effective method to produce functionalized particles for cellular uptake

In this contribution, a versatile approach for the synthesis of functionalized particles for drug delivery is presented, using two nonaggressive standardized procedures. The first procedure considered is the functionalization of an azido‐terminated α‐norbornenyl poly(ethylene oxide) (PEO) macromonomer with an alkyne‐containing active molecule via the copper catalyzed azide alkyne cycloaddition, click type reaction. The functionalized macromonomer is then polymerized by Ring‐Opening Metathesis Polymerization (ROMP) in dispersion to form functionalized particles. The second procedure consists in synthesizing particles by ROMP in dispersed media of norbornene with azido‐terminated α‐norbornenyl PEO macromonomer. The ROMP was initiated by the first generation Grubbs catalyst. Such functionalized core‐shell particles have stealthy properties due to their PEO shell and can be viewed as universal nanocarriers on which any alkyne‐modified active molecule can be grafted by click chemistry. © 2012 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem, 2013     

Computation of the invariant measure for a Lévy driven SDE: Rate of convergence

We study the rate of convergence of some recursive procedures based on some “exact” or “approximate” Euler schemes which converge to the invariant measure of an ergodic SDE driven by a Lévy process. The main interest of this work is to compare the rates induced by “exact” and “approximate” Euler schemes. In our main result, we show that replacing the small jumps by a Brownian component in the approximate case preserves the rate induced by the exact Euler scheme for a large class of Lévy processes.     

Measurement of Total and Unbound Mycophenolic Acid and Its Glucuronide by LC Coupled with MS. Application to a Pharmacokinetic Study of Mycophenolate Mofetil in Patients with Autoimmune Diseases

Liquid chromatography coupled with mass spectrometry for the determination of total and unbound mycophenolic acid and its major metabolite in human plasma has been developed. Sample preparations were based on a fully automated solid-phase extraction process and ultrafiltration. Mass spectrometric data were acquired in a single-ion monitoring method. The analytes and nevirapine (internal standard) were well separated in an isocratic mode over 8 min. Validation study exhibited excellent linearity, with intra- and inter-day precision and accuracy of less than 12%. The assay was successfully applied to the pharmacokinetic study of mycophenolic acid in patients with autoimmune diseases.     

Cold Molecules: Preparation,Applications, and Challenges

Research with cold molecules has developed rapidly in recent years. There is now a variety of established methods for cooling molecules into the millikelvin range. Nevertheless, a focal point of current research is directed toward finding new ways to bring the temperature of molecules even closer to absolute zero. Samples of cold molecules offer not only important applications for high‐resolution spectroscopy, which benefit from the increased interaction time of slow molecules with electromagnetic radiation; they also promise access to an exotic regime of chemical reactivity, in which phenomena such as quantum tunneling and quantum resonances predominate. This review begins with an introduction to the methods by which cold molecules can be prepared, with special emphasis on Stark deceleration and traps. In addition to applications of cold molecules that have already been partially achieved, an important focus of the review concentrates on possible future applications, and both aspects are illustrated with selected examples.