A Three-Component Synthesis of trifluoromethylated hexahydropyrrolo[1,2-a]imidazol-5-ones and hexahydropyrrolo[1,2-a]pyrimidin-6-ones

Chemistry of Heterocyclic Compounds - A three-component reaction of ethyl trifluoropyruvate, methyl ketones, and ethylenediamine or 1,3-diaminopropane afforded...     

Fluorine-Containing Furan-3(2Н)-Ones in Reactions with Binucleophiles: CF3vs C2F5

Chemistry of Heterocyclic Compounds - Five- and six-membered fluorine-containing azaheterocycles were synthesized based on available furan-3(2H)-ones, and the influence of the nature of the...     

Synthesis of fluorine-containing alkyl 2-cyano-3-oxocarboxylates. Reactions with nucleophiles

Fluorine-containing alkyl 2-cyano-3-oxocarboxylates were synthesized for the first time by the reaction of ethyl cyanoacetate with fluorine-substituted carboxylic acid halides or alkyl carboxylates. The reactions with hydrazine hydrate, phenylhydrazine, ando-phenylenediamine give hydrazinium (ammonium) enolates or products of acid decomposition. Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 10, pp. 1961–1965, October, 1999.     

A Rare Example of Discrete Lanthanide–Lithium Tetrakis-β-Diketonates: Synthesis,Structures, and Luminescence Properties

Russian Journal of Coordination Chemistry - The reactions of functionalized lithium CF3-β-diketonate (LiL) with europium(III) and terbium(III) chlorides in acetonitrile afford heterobimetallic...     

Synthesis of N-Alkyl Enamino Ketones Based on 3-Acyl-4H-polyfluorochromen-4-ones and Their Antimicrobial Activity

Russian Journal of Organic Chemistry - New N-substituted enamino ketones were synthesized by directed transformation of 3-acetyl- and 3-benzoyl-5,6,7,8-tetrafluoro-4H-chromen-4-ones by the action...     

Geometric isomerism in the series of fluoroalkyl-containing 1,2,3-trione 2-arylhydrazones

According to the ¹H, ¹³C, and ¹⁹F NMR data, fluoroalkyl-containing 1,2,3-trione 2-arylhydrazones in CDCl₃ exist exclusively, while in (CD₃)₂CO preferentially, as isomers in which the acyl or aroyl group is involved in intramolecular hydrogen bond. The isomer structure was assigned on the basis of the chemical shifts of the carbonyl carbon atoms and fluorine atoms and carbon-fluorine spin-spin coupling constants J _C-F. X-Ray diffraction data showed that 1,2,3-trione 2-arylhydrazones in crystal have the same structure as in CDCl₃ solution. Quantum-chemical calculations were performed to rationalize predominant formation of 1,2,3-trione 2-arylhydrazone isomers with a free polyfluoroacyl group.     

Polyfluorine-containing chromen-4-ones: synthesis and transformations

Theoretical and experimental data related to the chemistry of polyfluorinated 4H-chromen-4-ones were summarized and analyzed. The synthesis of the substances under investigation was reviewed. The aspects of reactivity, the routes for the functionalization of polyfluorinated 4H-chromen-4-ones and the formation of the novel heterocyclic systems on their basis are considered.     

Fluorinated 1,2,4-triketone analogs: new prospects for heterocyclic and coordination chemistry

The review is focused on the synthetic approaches to polyfluoroalkylated acetal-functionalized β-diketones and their cyclic derivatives (furan-3(2H)-ones and chromones) as analogs of 1,2,4-triketone. The synthetic possibilities of these compounds for construction of heterocycles and coordination compounds are considered.

     

Reduction of Trifluoromethyl-containing 4-Nitroso- and 4-Arylazopyrazoles as a Method for 4-Amino-3-trifluoromethylpyrazoles Synthesis

Russian Journal of General Chemistry - The processes of 4-nitroso-3-trifluoromethylpyrazoles reduction under various conditions were studied. It was found that their reduction with zinc in acetic...