A NOVEL REACTION BETWEEN Ge－Ge AND Fe－Fe BONDS IN COMPLEX （Me_2GeGeMe_2）［（η~5－C_5H_4）Fe（CO）］_2（μ－CO）_2 AND CRYSTAL STRUCTURE OF THE PRODUCT

ＡＮＯＶＥＬＲＥＡＣＴＩＯＮＢＥＴＷＥＥＮＧｅ－ＧｅＡＮＤＦｅ－ＦｅＢＯＮＤＳＩＮＣＯＭＰＬＥＸ（Ｍｅ_２ＧｅＧｅＭｅ_２）［（η~５－Ｃ_５Ｈ_４）Ｆｅ（ＣＯ）］_２（μ－ＣＯ）_２ＡＮＤＣＲＹＳＴＡＬＳＴＲＵＣＴＵＲＥＯＦＴＨＥＰＲＯＤＵＣＴ￥ＸｉｕＴ?..     

THE STUDY OF STRUCTURE AND DYNAMICS OF DINUCLEAR COMPLEXES ［Mo（VI）］_2－EDTA AND ［Mo（VI）］_2－EGTABY~1HNMR

ＴＨＥＳＴＵＤＹＯＦＳＴＲＵＣＴＵＲＥＡＮＤＤＹＮＡＭＩＣＳＯＦＤＩＮＵＣＬＥＡＲＣＯＭＰＬＥＸＥＳ［Ｍｏ（ＶＩ）］_２－ＥＤＴＡＡＮＤ［Ｍｏ（ＶＩ）］_２－ＥＧＴＡＢＹ~１ＨＮＭＲＲｕｉＦａｎｇＳＯＮＧ；ＦｅｉＬＩ；ＧｕａｎｇＭｉｎＬＩＵ；ＹｏｕＧａ?..     

HADAMARD TRANSFORM-MICROSCOPE THREE-DIMENSIONAL FLUORESCENCE IMAGE ANALYSIS

ＨＡＤＡＭＡＲＤＴＲＡＮＳＦＯＲＭ－ＭＩＣＲＯＳＣＯＰＥＴＨＲＥＥ－ＤＩＭＥＮＳＩＯＮＡＬＦＬＵＯＲＥＳＣＥＮＣＥＩＭＡＧＥＡＮＡＬＹＳＩＳ￥ＥｒＷｅｎＭＥＩ；ＸｉａｏＢｉｎＺＥＮＧ；ＧｕａｎＣｈｕａｎＣＨＥＮａｎｄＹｕｎ＇ｅＺＥＮＧ（Ｄｅｐａｒｔｍ...     

PARAMAGNETIC AND DIAMAGNETIC DICOPPER（Ⅱ） COMPLEXES WITH DI－SCHIFF BASE DERIVED FROM 2－HYDROXY－1－NAPHTHALDEHYDE AND1，3－DIANINO－2－PROPANOL

ＰＡＲＡＭＡＧＮＥＴＩＣＡＮＤＤＩＡＭＡＧＮＥＴＩＣＤＩＣＯＰＰＥＲ（Ⅱ）ＣＯＭＰＬＥＸＥＳＷＩＴＨＤＩ－ＳＣＨＩＦＦＢＡＳＥＤＥＲＩＶＥＤＦＲＯＭ２－ＨＹＤＲＯＸＹ－１－ＮＡＰＨＴＨＡＬＤＥＨＹＤＥＡＮＤ１，３－ＤＩＡＮＩＮＯ－２－ＰＲＯＰＡＮＯＬ...     

THECHEMICAL SELECTTVE ADDITION OF GRIGNARD REAGENT TO α－CINNAMOYL KETENE（1，2－ETHYLENE）DITHIOACETALS

ＴＨＥＣＨＥＭＩＣＡＬＳＥＬＥＣＴＴＶＥＡＤＤＩＴＩＯＮＯＦＧＲＩＧＮＡＲＤＲＥＡＧＥＮＴＴＯα－ＣＩＮＮＡＭＯＹＬＫＥＴＥＮＥ（１，２－ＥＴＨＹＬＥＮＥ）ＤＩＴＨＩＯＡＣＥＴＡＬＳ￥ＱｕｎｘｉｎＦＡＮＧ；ＣｈｕｎＬＩＮ；ＣｈａｎｇＳｈａｇＺＨＡＮＧ...     

THE STACKING INERACTION OF TERNARY COMPLEXES OF Zn(ATP)~(2-)AND PYRIDINE-LIKELIGANDS

ＴＨＥ　ＳＴＡＣＫＩＮＧ　ＩＮＥＲＡＣＴＩＯＮ　ＯＦ　ＴＥＲＮＡＲＹ　ＣＯＭＰＬＥＸＥＳ　ＯＦ　Ｚｎ（ＡＴＰ）~（２－）ＡＮＤ　ＰＹＲＩＤＩＮＥ－ＬＩＫＥＬＩＧＡＮＤＳＴＨＥＳＴＡＣＫＩＮＧＩＮＴＥＲＡＣＴＩＯＮＯＦＴＥＲＮＡＲＹＣＯＭＰＬＥＸＥＳＯ?..     

SYNTHESES AND PROPERTIES OF POLY（N－ISOPROPYLACRYLAMIDECO－N－ACRYLOXYSUCCINIMIDE）AND ITS IgG－CONJUGATE

ＳＹＮＴＨＥＳＥＳＡＮＤＰＲＯＰＥＲＴＩＥＳＯＦＰＯＬＹ（Ｎ－ＩＳＯＰＲＯＰＹＬＡＣＲＹＬＡＭＩＤＥＣＯ－Ｎ－ＡＣＲＹＬＯＸＹＳＵＣＣＩＮＩＭＩＤＥ）ＡＮＤＩＴＳＩｇＧ－ＣＯＮＪＵＧＡＴＥ￥ＹｉｎｇＷＡＮＧ；ＲｅｎＸｉＺＨＵＯ（Ｄｅｐａｒｔｍｅｎｔｏ...     

LEWIS ACID PROMOTFED ASYMMETRIC ENE－REACTION OF（－）－MENTHYL GLYOXYLATE WITH HOMOALLYL SILYL ETHER

ＬＥＷＩＳＡＣＩＤＰＲＯＭＯＴＦＥＤＡＳＹＭＭＥＴＲＩＣＥＮＥ－ＲＥＡＣＴＩＯＮＯＦ（－）－ＭＥＮＴＨＹＬＧＬＹＯＸＹＬＡＴＥＷＩＴＨＨＯＭＯＡＬＬＹＬＳＩＬＹＬＥＴＨＥＲＹｏｎｇＪｕｎＣＨＥＮ；ＤｏｎｇＷＡＮＧ；ＪｉＳｈｅｎＬＩ（Ｉｎｓｔｉｔｕｔｅ...     

SYNTHESIS AND ANTI－HUMAN IMMUNODEFICIENCY VIRUS－1（HIV－1） ACTIVITY OF 9－（2－PHOSPHONYLMETHOXYETHYL）ADENINE （1）AND ITS REGIOISOMER 3－（2－PHOSPHONYLMETHOXYETHYL）ADENINE（2）

ＳＹＮＴＨＥＳＩＳＡＮＤＡＮＴＩ－ＨＵＭＡＮＩＭＭＵＮＯＤＥＦＩＣＩＥＮＣＹＶＩＲＵＳ－１（ＨＩＶ－１）ＡＣＴＩＶＩＴＹＯＦ９－（２－ＰＨＯＳＰＨＯＮＹＬＭＥＴＨＯＸＹＥＴＨＹＬ）ＡＤＥＮＩＮＥ（１）ＡＮＤＩＴＳＲＥＧＩＯＩＳＯＭＥＲ３－（２－ＰＨＯ...     

SYNTHESIS AND STRUCTURE OF A 2D SHEET－LIKE COPPER（II） COMPLEX WITH BRIDGING PYRIDINE－4－CARBOXYLATE AND TRANS－OXAMIDATE LIGANDS

ＳＹＮＴＨＥＳＩＳＡＮＤＳＴＲＵＣＴＵＲＥＯＦＡ２ＤＳＨＥＥＴ－ＬＩＫＥＣＯＰＰＥＲ（ＩＩ）ＣＯＭＰＬＥＸＷＩＴＨＢＲＩＤＧＩＮＧＰＹＲＩＤＩＮＥ－４－ＣＡＲＢＯＸＹＬＡＴＥＡＮＤＴＲＡＮＳ－ＯＸＡＭＩＤＡＴＥＬＩＧＡＮＤＳ￥ＭｅｉＦａｎｇＷｕ；Ｚｈ...     

Identification and quantification of the volatile constituents in Cnidium monnieri using supercritical fluid extraction followed by GC‐MS

The volatile components of Cnidium monnieri were obtained by supercritical fluid extraction (SFE) and analyzed by GC‐MS (identification and determination of metabolites). The compounds were identified according to their retention times and mass spectra. The effects of different parameters, such as extraction pressure, temperature, dynamic extraction time, flow rate of CO₂, on the SFE of C. monnieri extracts were investigated. A total of 14 compounds of SFE extracts were identified. Osthole (69.52%), bornyl acetate (10.03%), α‐pinene (4.71%), and imperatorin (2.42%) were the major compounds identified in C. monnieri SFE extracts. The quantitation of osthole and imperatorin were then accomplished. The linear calibration ranges were all 5–1000 μg/mL for osthole and imperatorin by GC‐MS analysis. The recovery of osthole and imperatorin were in the range 96.5–101.8%. The LODs for osthole and imperatorin were 1.0 and 0.6 μg/mL, respectively.     

Modeling of supercritical fluid extraction of flavonoids from Calycopteris floribunda leaves

The aim of this study was to obtain flavonoids extracts from Calycopteris floribunda leaves using supercritical fluid extraction (SFE) with CO₂ and a co-solvent. Pachypodol, a potential anticancer drug lead compound separated from the extracts, was examined. Classical organic solvent extraction (CE) with ethanol was performed to evaluate the high pressure method. HPLC analysis was introduced to interpret the differences between SFE and CE extracts in terms of antioxidant activity and the concentration of pachypodol. SFE kinetics and mathematical modeling of the overall extraction curves (OEC) were investigated. Evaluation of the models against experimental data showed that the Sovová model performs the best. The supercritical fluid extraction process was optimized using a central composite design (CCD), where temperature and pressure were adjusted. The optimal conditions of SFE were: pressure of 30 MPa and temperature of 35°C.     

Supercritical fluid extraction of flavonoids from Scutellariae Radix

An optimal condition of supercritical fluid extraction (SFE) for flavonoids of Scutellaria baicalensis was developed. In this study, various temperatures, pressures and modifiers were studied. The conventional extraction methods were conducted in parallel for comparison. The crude extracts were qualitatively compared by TLC and GC–MS, and the contents of flavonoids were determined by HPLC. The amounts of baicalin, baicalein and wogonin in the Scutellariae Radix obtained by supercritical fluid extraction and a conventional sonic shaking method were 137.6 mg/g, 8.6 mg/g and 2.2 mg/g, 113.5 mg/g, 5.7 mg/g and 2.3 mg/g, respectively. Application of SFE for extraction of the flavonoids from Scutellariae Radix was preferable. The optimal conditions of SFE was as follows: supercritical carbon dioxide–MeOH–water (20:2.1:0.9), 50°C and 200 bar.     

Supercritical fluid extraction of kava lactones from Piper methysticum (kava) herb

Supercritical fluid extraction of kava lactones from Piper methysticum Forst. herb is described here. The extraction was performed with supercritical carbon dioxide alone and supercritical carbon dioxide modified with 15% ethanol, and the extracts were analyzed by gas chromatography/mass spectrometry. Seven lactones including: 7,8-dihydrokavain; kavain; 5,6-dehydrokavain; 5, 6, 7, 8-tetrahydroyangonin; dihydromethysticin; yangonin; and methysticin were the major constituents in the SFE extract.     

Supercritical fluid extraction of oxindole alkaloids from Uncaria tormentosa

Supercritical fluid extraction of oxindole alkaloids from Uncaria Tormentosa is described. The extraction was performed with supercritical carbon dioxide alone and with supercritical carbon dioxide modified with 10% metanol, and the extracts were analyzed by GC/MS and HPLC/MS.     

褐煤超临界流体抽提产物中芳烃的组成特征

用柱色谱分离、ＧＣ／ＭＳ分析云南先锋和金所褐煤甲苯（或二甲苯）超临界流体抽提（ＳＣＦＥ）产物油段分中芳烃馏分的组成结构，鉴定出联苯、联苄型结构及它们的烷基衍生物为主要组成部分，菲、芴、芘、荧蒽、苯并芘等多环缩合芳烃的量较少，有较丰富的芳构化五环萜类，包括从三环至五环芳构化的化合物。这些结果反映了多环芳烃成煤过程中的演变情况，可为煤化学研究提供重要的信息。     

A two-step supercritical fluid extraction of polycyclic aromatic hydrocarbons from roadside soil samples

A two-step procedure for the supercritical fluid extraction (SFE) of polycyclic aromatic hydrocarbons from soil samples was developed. The procedure consists of a static supercritical fluid treatment in a closed extraction cell at a high temperature (T=250 or 340degreesC for 20 min) and an SFE with a solvent trapping. During the static phase, the sample is exposed to a supercritical organic solvent (methanol, toluene, dichloromethane, ACN, acetone, and hexane). The solvent penetrates particles of the matrix to substitute strongly bonded molecules and dissolves the analytes in the supercritical phase. At ambient temperature, supercritical fluids became liquid and lost their solvation abilities. Most of the analytes condense on the surface of the particles or on the extraction cell walls without forming strong bonds or penetrating deep into the matrix. Thus, the pretreatment liberates the analytes and they behave similar to those in freshly spiked samples. The common SFE with toluene-modified CO2 as an extraction fluid follows the static phase. With the use of the most suitable extraction phases (toluene, ACN), the extraction efficiency of the combined procedure is much higher (approximately100%). The results of the combined procedure are compared to the SFE procedure of the same untreated sample (difference less than 5%) and to the Soxhlet extraction. The extracts were analyzed using a GC with the flame ionization detection.     

北苍术超临界CO2萃取产物的成分

用气相色谱－质谱－计算机联用法分析了北苍术的超临界CO2萃取产物的成分,鉴定出苍术酮、β－桉叶油醇、苍术醇31化合物,占出峰总面积的88．1％,并与传统水蒸汽蒸馏法（SD）提取的挥发油成分进行了对比。结果证明,两种方法抽提的苍术主成分基本相同,但超临界CO2萃取产物比SD产物多出现了一些重质组分,萃取更完全而有效。     

Determination of PAHs in dust from Shanghai by optimized SFE and GC/MS

EPA 16 priority polycyclic aromatic hydrocarbons (PAHs) were extracted from dust by supercritical fluid extraction (SFE). Parameters (pressure, temperature and time) affecting the collection efficiencies of PAHs were assessed according to the extraction efficiency, and 30 MPa, 80 degrees C and 30 min dynamic extraction time were confirmed to be the best and simplest conditions of SFE to extract 16 priority PAHs from dust. The characterization of the extracts was carried out by gas chromatography with mass detector in selective ion mode (GC/MS/SIM). Ultrasonic extraction (USE) was used as a comparison with SFE. The results showed that the SFE method has a better efficiency than USE for the extraction of PAHs in dust. With the optimized conditions of SFE, the distribution of PAHs in dust samples in urban areas of Shanghai from Mar 10, 2005 to May 28, 2005 was investigated. The results demonstrated that traffic emission, especially from gasoline engines, was the main source of PAHs in dust of Shanghai.     

Comparative analysis of the oil and supercritical CO(2) extract of Schinus molle L. growing in Yemen

In this study, we report the preliminary data on the chemical composition of Yemeni Schinus molle L. volatile oil obtained by supercritical extraction with carbon dioxide (40°C and 90?bar), SFE, and by hydrodistillation (HD). The composition of the volatile oil has been analysed by GC and GC-MS. The content of the major constituents in the oils from leaves varied in the following ranges: germacrene D 3.7% in SFE and 16.7% in HD; β-caryophyllene 19.1% in SFE and 13.5% in HD. The amount of monoterpenes constituted 4%, in all the analysed samples, while the number of sesquiterpenes was 44% in supercritical and 67% in HD oil. Some compounds were not identified by GC-MS and it will require further analysis using other analytical techniques.