共查询到20条相似文献,搜索用时 31 毫秒
1.
Adel A.-H. Abdel-Rahman Ahmed E.-S. Abdel-Megied Hamed M. Abdel-Bary Abdel-Aleem H. Abdel-Aleem Emad M. I. Morcy Mohamed T. Shabaan 《Monatshefte für Chemie / Chemical Monthly》2009,140(5):559-564
Abstract A series of peptide derivatives conjugated with N1-protected tryptophan residue was synthesized. The prepared compounds were tested for antimicrobial activity against four
different bacterial species displaying different degrees of antibacterial activities or inhibitory actions.
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2.
Mohamed A. A. Radwan Marwa A. Shehab Siham M. El-Shenawy 《Monatshefte für Chemie / Chemical Monthly》2009,140(4):445-450
Abstract 5-Aminobenzo[b]thiophene-2-carboxylic acid was converted to the corresponding 5-(2-chloroacetamido)benzo[b]thiophene-2-carboxylic acid by reaction with chloroacetyl chloride. This acetamido product was treated with different alkyl,
cycloalkyl, aryl, and heterocyclic amines to afford a series of C5-substituted benzo[b]thiophenes. These compounds were found to possess potent anti-inflammatory activity.
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3.
Abstract One-pot, three-components synthesis of 2,4,6-triarylpyridines and 5-unsubstituted-3,4-dihydropyrimidin-2(1H)-ones was performed under solvent-free conditions using molecular iodine as the catalyst in moderate to good product yields.
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4.
Manas Chakrabarty Sulakshana Karmakar Ratna Mukherjee Shiho Arima Yoshihiro Harigaya 《Monatshefte für Chemie / Chemical Monthly》2009,140(4):375-380
Abstract 1-Alkyl/phenyl-2-arylbenzimidazoles have been synthesized in very good to excellent yields by a one-pot condensation of N-alkyl/phenyl-o-phenylenediamines with aryl aldehydes in water at room temperature using cetylpyridinium bromide as a cheap and eco-friendly
catalyst.
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5.
Mohammad Rahimizadeh Mehdi Pordel Mehdi Bakavoli Zahra Bakhtiarpoor Ala Orafaie 《Monatshefte für Chemie / Chemical Monthly》2009,140(6):633-638
Abstract New imidazo[4,5-a]acridone derivatives were synthesized from the rearrangement of 3H-imidazo[4′,5′:3,4]benzo[c]isoxazoles. New imidazo[4,5-a]acridines were obtained from the reaction of imidazo[4,5-a]acridones in boiling POCl3. All of these compounds exhibited antimicrobial activities comparable to streptomycin as reference drug.
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6.
Bożena Modzelewska-Banachiewicz Barbara Michalec Teresa Kamińska Liliana Mazur Anna E. Kozioł Jacek Banachiewicz Marzena Ucherek Martyna Kandefer-Szerszeń 《Monatshefte für Chemie / Chemical Monthly》2009,140(4):439-444
Abstract (Z)-3-(3,4-diaryl-1,2,4-triazole-5-yl)prop-2-enoic acid derivatives were obtained in the course of the reaction of N
3-substituted amidrazones with maleic anhydride, and isomerized into the (E) isomers by heating under reflux in acetic acid solution. The molecular structure of the compounds obtained was confirmed
by IR and 1H NMR spectroscopy, and by X-ray crystallography for (2E)-3-(4,5-diphenyl-4H-1,2,4-triazol-3-yl)prop-2-enoic acid. The antiviral and immunomodulating activity of several of the compounds was examined.
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7.
Zhi-zhong Wang Wei Jiao Guang-yun He Run-hua Lu 《Monatshefte für Chemie / Chemical Monthly》2009,140(1):79-81
Abstract A simple method for the straightforward regioselective synthesis of 2,3-mannoepoxy-β-cyclodextrin, which is a valuable precursor for further functionalization of β-cyclodextrin, is achieved under aqueous conditions without any organic solvents at a moderate yield.
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8.
Bakr F. Abdel-Wahab Hatem A. Abdel-Aziz Essam M. Ahmed 《Monatshefte für Chemie / Chemical Monthly》2009,140(6):601-605
Abstract Potassium hydrazinecarbodithioate were prepared by treatment of acid hydrazides with carbon disulfide in the presence of potassium
hydroxide. Reaction of this potassium salt with hydrazine hydrate, phenacyl bromide, or hydrazonoyl chlorides afforded 1,2,4-triazole,
1,3-thiazole, and 1,3,4-thiadiazoles. Reaction of 1,2,4-triazole with phenacyl bromide or hydrazonoyl chlorides afforded the
corresponding 1,2,4-triazolo[3,4-b][1, 3, 4]-thiadiazines. All these new compounds were screened for antibacterial and antifungal activity. Some had promising
activity.
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9.
Said Aly Said 《Monatshefte für Chemie / Chemical Monthly》2009,140(5):573-579
Abstract A series of pyridines, pyrimidines, and their derivatives were synthesized using 2-amino-6-methyl-4-phenylnicotinonitrile
as starting material. Thirteen new heterocyclics containing a pyridine ring were thus prepared. Pharmacological screening
showed that many of these compounds have good anti-inflammatory and analgesic activity comparable with those of diclofenac
potassium and valdecoxib as reference drugs. Assignment of the structures of the new compounds was based on chemical and spectroscopic
evidence. Synthesis, spectroscopic data, and pharmacological properties of the compounds are reported in detail.
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10.
Application of various ionic liquids as cosolvents for chloroperoxidase-catalysed biotransformations
Abstract Chloroperoxidase from Caldariomyces fumago catalyses oxidation of indole and thioanisole in reaction mixtures containing up to 40% (v/v) of different ionic liquids (ILs). Results indicate that ILs containing tosylate, trifluoroacetate, chloride, and methylsulfate
anions are suitable cosolvents for these transformations, yielding high enantiomeric excess and good conversion rates.
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11.
Barahman Movassagh Mohammad Soleiman-Beigi 《Monatshefte für Chemie / Chemical Monthly》2009,140(4):409-411
Abstract A simple, highly efficient, and green protocol has been developed for preparation of sulfides from alkyl or aryl thiols and
benzyl-, allyl-, t-butyl, and adamantyl halides under solvent- and catalyst-free conditions.
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12.
Heinrich Berger Werner Seebacher Marcel Kaiser Reto Brun Robert Saf Robert Weis 《Monatshefte für Chemie / Chemical Monthly》2009,140(5):495-502
Abstract Several 4-amino-6,7-diarylbicyclo[2.2.2]octan-2-ols bearing varying substituents on the aromatic rings were synthesized following
a manual method for applying the Hansch approach. All new compounds were tested for their activity against the causative organisms
of East African sleeping sickness and malaria tropica. Structure activity relationships are discussed.
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13.
Bohumil Proksa Richard Hercek Tibor Liptaj Nada Prónayová 《Monatshefte für Chemie / Chemical Monthly》2009,140(5):485-487
Abstract A new compound was isolated from the reaction mixture after O-demethylation of 6-O-acetyl-10α-acetoxycodeine with boron tribromide. The structure of this compound, 10α-hydroxy-β-isomorphine, was elucidated by spectral data, and its spatial arrangement was deduced from an NOE experiment. Capillary zone
electrophoresis was used for separation of morphine and its 10-hydroxy analogues.
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14.
Maher F. El-Zohry Thanaa A. Mohamed Essam M. Hussein 《Monatshefte für Chemie / Chemical Monthly》2009,140(3):265-272
Abstract 2-Methylbenzimidazole 1 reacted with 3-dicyanomethylidine-1-ethyl-2-oxoindoline 2 in ethyl acetate to afford 1-amino-2-cyano-3,4-dihydro-1′-ethylspiro{benzimidazo[1,2-a]pyridine-3,3′-indolin}-2′-one 6, which was used as a key intermediate in the synthesis of fused spiropolyheterocyclic derivatives of benzimidazopyridopyrimidine
and/or benzimidazonaphthyridine nucleus incorporating an indoline moiety.
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15.
Rahman Hosseinzadeh Mahmood Tajbakhsh Maryam Mohadjerani Zahra Lasemi 《Monatshefte für Chemie / Chemical Monthly》2009,140(1):57-60
Abstract Ethylenebis(N-methylimidazolium) ditribromide, a stable crystalline solid, is easily prepared by reaction of the corresponding dibromide
salt with bromine in n-hexane. 1,3-Diketones and β-ketoesters can be brominated chemoselectively to the corresponding α-monobrominated products
by using this reagent at 0–5 °C. Under the same reaction conditions, diethyl malonate, ethyl cyanoacetate, and malonitrile
were monobrominated at moderate yield.
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16.
Raghunath B. Toche Bhausaheb K. Ghotekar Muddassar A. Kazi Madhukar N. Jachak 《Monatshefte für Chemie / Chemical Monthly》2009,140(2):235-241
Abstract A novel method for the synthesis of 3-(2-substituted ethyl)-2-methylbenzohetero[3,2-a]pyrimidines in high yield (80–85%) was achieved, which involves a dihydrofuranone intermediate, readily obtained from β-ketolactone
to 2-aminobenzoheterocycles. The major advantage of the methodology is the high yield and product purity.
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17.
Marco Rupprich Clemens Decristoforo Barbara Matuszczak 《Monatshefte für Chemie / Chemical Monthly》2009,140(4):405-407
Abstract In contrast to the results presented in a previous report, the direct conversion of alcohols to alkyl fluorides with triphenylphosphine
and potassium fluoride in CCl4/DMF under mild conditions failed.
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18.
Abolghasem Davoodnia Mehdi Bakavoli Mehdi Soleimany Niloofar Tavakoli-Hoseini 《Monatshefte für Chemie / Chemical Monthly》2009,47(3):355-358
Abstract A new route to the synthesis of 2-arylthieno[2,3-d]pyrimidin-4(3H)-ones has been developed through heterocyclization of 2-amino-4,5-dimethylthiophene-3-carboxamide
with aromatic aldehydes in boiling glacial acetic acid followed by air oxidation. The unoxidized intermediates, 2-aryl-2,3-dihydrothieno[2,3-d]pyrimidin-4(1H)-ones, are isolated when the reactions are carried out either at room temperature or under a nitrogen atmosphere.
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19.
Ch. Sree Lakshmi H. Rehaman Adari Bhaskar Rao 《Monatshefte für Chemie / Chemical Monthly》2009,140(6):611-613
Abstract The enzymatic cyclization of phenoxyacetylcyanomethylenetriphenylphosphorane derivatives using pre-treated baker’s yeast cells,
a rapid one-pot assembly of heteromacrocyclic compounds, is described.
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20.
Nipawan Pongprom Gerhard Müller Peter Schmidt Wolfgang Holzer Helmut Spreitzer 《Monatshefte für Chemie / Chemical Monthly》2009,140(3):309-313
Abstract A series of carbinols has been synthesized by attachment of different piperidinyl side chains to the quinone structure of
azanaphthoquinone annelated pyrroles. The synthesized compounds were screened for their cytotoxic activities. Compared to
previously published results, they exhibited only moderate activities, thus showing that the existence of the quinone moiety
seems to be essential for anticancer activities of this group.
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