A chemoenzymatic synthesis of 3,4,5,6-tetrahydro-2H-benzo[b][1,4]-oxazocine-3,5-dione and its derivatives |
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| Authors: | Ch Sree Lakshmi H Rehaman Adari Bhaskar Rao |
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| Institution: | (1) Organic Chemistry Division, Indian Institute of Chemical Technology, Hyderabad, 500 607, India |
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| Abstract: | Abstract The enzymatic cyclization of phenoxyacetylcyanomethylenetriphenylphosphorane derivatives using pre-treated baker’s yeast cells,
a rapid one-pot assembly of heteromacrocyclic compounds, is described.
Graphical abstract
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| Keywords: | Baker’ s yeast Cyclization Macrocyclic Aqueous medium Green chemistry |
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