分析化学实验课程教学大纲的标准化改造与构建

基于工程教育专业认证标准的要求,结合专业课程的特点,对我校制药工程专业的分析化学实验教学大纲进行了标准化改造。标准化的教学大纲更加突出了专业适用性,关联了教学要求与教学内容和考核评定,增加了考核量化指标与课程持续改进的方式,进一步规范了分析化学实验课程的教学。标准教学大纲的构建为实验教学活动提供了更加明确的指导,有利于缩小不同教师教学的差异性,保证了实验教学的质量,为建立可持续完善的工程类实验教学标准体系提供了具体参考。     

储氢合金电极的表面修饰研究

利用等离子体技术对AA型MH/Ni电池的储氢合金电极进行了镀覆导电膜层的表面修饰,用XRD及SEM对电极结构进行了表征.极片经过表面修饰的电池,其内阻降低了24％,放电容量有了明显提高,5C (7.5 A) 放电容量提高了200 mA•h,放电平台电压提高了约0.14 V,导电膜层还起到了电极保护层的作用,抑制了合金的粉化,提高了电池的循环稳定性.同时,电池内压显著降低,电池性能有了较大改善.     

促进学生认识发展的“电离和离子反应”专题的单元整体教学研究

系统梳理了电离、离子反应专题的已有研究,分析了电离、离子反应内容对学生认识发展的作用,进而确立了化学1模块电离、离子反应专题的教学论问题并进行了阐述分析。在上述研究的基础上,设计了化学1模块电离、离子反应专题的单元整体教学,并进行了教学实践,取得了较好的教学效果。     

基础化学实验室的建设与管理

化学实验室是全面完成化学教学任务的重要基地。 我院2002年建立了设备比较先进的化学实验室,给学生创造了良好的实验条件,并进行了科学化的管理,规定了各种规章制度和有关职责,较好地完成了化学教学任务。在实践中。采取：固定优秀代课教师兼管,勤工助学学生帮忙的管理办法,既减轻教师的劳动强度,又培养了学生的技能,且协调了各种关系,有利于化学教学质量的提高。     

前言

自20世纪初期,德国化学家EmilFischer首先合成了甘氨酸二肽片段,并第一次提出“peptide”（多肽）这一名词,多肽化学的研究已经历了100多年的发展．1953年,Vigneand小组首次完成了生物活性肽催产素的合成,并因此于1955年获得了诺贝尔化学奖．1963年,Merrifield提出了多肽固相合成法,并发明了第一台多肽自动合成仪,大大简化了多肽合成的流程、提高了合成的效率,从而促使多肽化学实现了飞跃式发展,Merrifield也因此获得了1984年诺贝尔化学奖．1965年,我国科学家完成了牛结晶胰岛素的合成,     

无机化学微信平台的构建与实践研究

针对无机化学传统教学模式的不足,构建了无机化学微信平台。介绍了构建平台必需的微信公众号和微信群的建立过程和方法。分析了无机化学微信平台在教学中的实践效果,弥补了传统教学中的不足。讨论了无机化学微信平台的积极作用,提高了教师教学水平和学生的学习能力,达到了师生双赢的目的。     

非理想气体的逸度因子和非理想溶液的活度系数

对单组分非理想气体,推导了它的逸度因子的微分方程式。对多组分非理想气体,推导了各组分逸度因子满足的微分方程式,定义了一个总逸度因子,并找到了总逸度因子和各组分逸度因子之间的关系。同样,对非理想溶液,推导了各组分活度系数满足的微分方程式,定义了非理想溶液的总活度系数,并找到了两者满足的关系。最后分析了逸度因子和活度系数之间的异同点。     

基于“HEART”理念的化学实验教学改革研究

为提高实验教学质量,分析当前实验教学存在的问题,创建先进的“HEART”实验教学理念。以此教学理念为指导,开展了化学实验教学体系、教学方法、教学团队、教学质量评价研究。建立了“二渗透、四结合”的实验教学体系,培养了学生的创新精神和实践能力;形成了以学生为中心的快乐实验教学方法,激发了学生实验的积极性和创造性;建立了实验教学质量评价体系,完善激励机制,敦促教师不断提高实验教学能力;建立了柔性的实验教学改革运行机制,形成了教学改革长效机制。     

铁(III)催化多卤代变色酸双偶氮胂类试剂的褪色反应特性及其应用

本文研究了铁(III)催化H2O2还原多卤代变色酸双偶氮胂类试剂(PHA)的褪色反应动力学行为, 测定了反应级数和反应活化能, 获得了经验速率方程, 探讨了反应机理, 稳态处理后的动力学方程与经验速率方程相吻合, 说明了机理的合理性。并以三氯偶氮胂为指示反应试剂, 测定了人发中痕量铁的含量, 得到了满意的结果。     

共聚反应单体竞聚率测定实验的设计与实践

通过实际教学情况,设计实施了共聚反应单体竞聚率测定的设计性教学实验,并以核磁共振的方法进行结果测定。通过实验教学,学生掌握了温度变化对竞聚率影响的实验方法,提高了理论联系实际的能力,使抽象理论实际化,让学生初步建立起抽象与具体的联系,并且充分拓展了学生的视野和思维。在增加了实验趣味性的同时也优化了教学方式和课程体系,取得了良好的教学效果。     

碱性鲁米诺体系在玻碳和铂电极上的电位分辨电致化学发光研究

提出一种使用循环伏安（ＣＶ）扫描电位下的电致化学发光（ＥＣＬ）研究方法,在自制的仪器系统中同时进行ｉ－Ｅ和Ｉ－Ｅ测量,获得对应的ＣＶ和电位分辨的电致化学发光（ＰＲＥＣＬ）曲线。首先发现碱性鲁米诺体系在玻碳电极（ＧＣＥ）上呈现２个阳极发光峰（在０．３２Ｖ、０．３９Ｖｖｓ．Ａｇ）和１个阴极发光峰（在－０．６２Ｖ）,在Ｐｔ电极上呈现２个阳极发光峰（在０．４９Ｖ、０．７５Ｖ）。结合ＣＶ、一阶微分伏安、Ｃｌ     

原位拉曼技术研究Mo催化剂的还原和硫化

运用原位激光拉曼技术研究了Mo/Al_2O_3和Mo/TiO_2-Al_2O_3催化剂的氢还原和硫化行为．结果清楚显示，两种载体上不同配位形态的Mo物种的氢还原能力有明显差异，其硫化性能也不相同．TiO_2对Al_2O_3表面的复盖可显著促进Mo物种的还原和硫化。     

The teaching of Analytical Chemistry in Norway

Summary Training in Analytical-Chemistry at the University of Oslo, at the Oslo Technical College and at the School for Medical Technologists at Oslo University Hospital is briefly outlined.Presented at Euroanalysis III conference, Dublin, August 20–25, 1978     

Photoluminescence Properties of Silica Aerogel During Sintering Process

We report photoluminescence spectra measured for two series of silica aerogel sintered at 1000°C in different time intervals. In the photoluminescence spectra of nonsintered sample, bands at 1.8, 2.0 and 2.2 eV are identified. During sintering process, the bands at 1.8 and 2.0 eV decrease and vanish, while the band at 2.2 eV shows more complicated behavior. According to infrared spectra of the same samples we find that the photoluminescence band at 1.8 eV originates from nonbridged oxygen hole center defect, and that at 2.0 eV originates from silane in the gel network. Nonstoichiometric SiOx causes photoluminescence band at 2.2 eV.     

Thermodynamic properties of peptide solutions: 14. Partial molar expansibilities and isothermal compressibilities of some glycyl dipeptides in aqueous solution

The partial molar volumes at infinite dilution have been obtained for a series of glycyl dipeptides in aqueous solution at 15, 30, and 35°C. These results have been combined with data obtained at 25°C, that were reported earlier, to evaluate the partial molar expansibilities at infinite dilution for the dipeptides at 25°C. These quantities, along with the partial molar heat capacities and isentropic compressibilities at infinite dilution that were reported in previous studies, were used to derive the partial molar isothermal compressibilities at infinite dilution for the glycyl dipeptides at 25°C. The results obtained are rationalized in terms of the hydration of the constituent groups of the dipeptides.     

X-ray diffraction study of the structure of Al-Co melts

The structure of Al-Co melts with 0 at.%, 10 at.%, 18 at.%, 23.5 at.%, 26 at.%, 80.7 at.%, and 100 at.% Co has been studied by X-ray diffraction. Inverse Monte Carlo simulation using the experimental curves of the structural factor was employed to reconstruct the models of melts, analyzed by the Voronoi-Delaunay technique. The dependence of parameters that define short-and longer range ordering of atoms is nonmonotonous in the range 85–74 at.% Al and is extremal in the vicinity of a melt with 76.5 at.% Al. In the stated range of concentrations, the cobalt atoms basically lie at distances of ≈4.2 Å in the pentagonal rings of icosahedral type polytetrahedral clusters. Therefore one can speak about correlation in the character of atomic ordering in melts and corresponding periodic and quasiperiodic phases.     

Preparative scale mass spectrometry: A brief history of the calutron

Calutrons were developed in the laboratory of E. O. Lawrence at the University of California at Berkeley. They were a modification of the cyclotrons he had invented and used in his Nobel Prize‐winning investigations of the atomic nucleus. At the time their construction was undertaken, calutrons represented the only certain means of preparing enriched uranium isotopes for the construction of a fission bomb. The effort was successful enough that every atom of the 42 kg of ²³⁵U used in the first uranium bomb had passed through at least one stage of calutron separation. At peak production, the first stage separators, α tanks, yielded an aggregate 258‐g/day ²³⁵U enriched to about 10 at. % from its natural abundance level of 0.72 at. %. The second stage separators, β tanks, used the 10 at. % material as feedstock and produced a total 204‐g/day ²³⁵U enriched to at least 80 at. %. The latter, weapons grade, material was used in fission bombs. Under typical operating conditions, each α tank operated at a uranium beam intensity at the collectors of approximately 20 mA and each β tank at a beam intensity of approximately 215 mA at the collectors. Bulk separation of isotopes for bomb production ceased in 1945. Since that time calutrons have been used to separate stable isotopes, but on a more limited scale than wartime weapons production. Stable isotope separations since 1960 have taken place using one modified β tank.     

Electrochemical determination of adenine and adenosine: adsorption of adenine and adenosine at the pyrolytic graphite electrode

Adenine and adenosine are polarographically reducible from aqueous solution at pH 4.7 at the DME at the same E(1 2 ) and are also voltammetrically oxidizable at the PGE, but at different potentials, adenosine at higher potentials. Competitive adsorption of both compounds at the PGE results in a decrease in the scanning voltammetric oxidation peak of adenine in the presence of adenosine, reaching a constant value when the concentration of the latter is above 6 mM. In mixtures, the sum of the two is obtained by polarography at the DME. Solid adenosine is then added to the solution and the adenine is determined by voltamrnetry at the PGE.     

Fluorescence anisotropy of acridinedione dyes in glycerol: Prolate model of ellipsoid

Time-dependent reorientations of resorcinol-based acridinidione (ADR) dyes in glycerol were studied using steady-state and time-resolved fluorescence studies. The difference between fluorescence anisotropy decays recorded at 460 nm when exciting at 250 nm and those obtained when exciting at 394 nm are reported. When exciting at 394 nm, the fluorescence anisotropy decay is bi-exponential, while on exciting at 250 nm a mono-exponential fluorescence anisotropy decay is observed. We interpret this in terms of different directions of the absorption dipole at 394 and 250 nm with the emission dipole respectively, which is experimentally validated and further analysed as a prolate model of ellipsoid.